... chromosomes. The fidelity of chromosome transmission is enhanced not only by the geometry of stable centromere–MT interac- tions, but also by the action of a centromere-based regulatory system called the ... and SCC and the relationship between them. THENATUREOFCENTROMERIC CHROMATIN Centromeres are defined genetically by phenotypic or molecular markers [31] that always segregate a...
Ngày tải lên: 31/03/2014, 21:21
... their analysis to candidate genes and pathways involved in high-altitude physiology, PRKAA1 and NOS2A are the best-supported candidates in the Andeans and EPAS1 is the best candidate in the Tibetans. ... 38 and 14 candi- date regions in the Andeans and Tibetans, respectively. Interestingly, there is no overlap in candidate regions identified in the two populations. Wh...
Ngày tải lên: 09/08/2014, 20:22
Báo cáo y học: "Measuring the impact of apnea and obesity on circadian activity patterns using functional linear modeling of actigraphy data" pps
... activity patterns and test the null hypothesis that circadian activity patterns are the same regardless of apnea and BMI values. The alterna- tive hypothesis is that apnea, BMI, and/ or their interac- tion ... with the same magnitude of activity, low activity in the morning and high activity in the afternoon, their average activity may be similar, and a significant differ...
Ngày tải lên: 10/08/2014, 09:20
Báo cáo khoa học: "Bridging the Gap between Dictionary and Thesaurus" pptx
... similarity score matrix B for the WN synsets and the ROGET classes. A simi- larity score B(j, k) is computed for the jth WN synset (taking the synset itself, the hypernyms, and the coordinate ... setting az = 3, a2 = 5 and as = 2 to reveal the relative significance of finding a synonym, a hypernym, and any word in the textual gloss respectively in the dictio...
Ngày tải lên: 31/03/2014, 04:20
Báo cáo Y học: Cold induces stress-activated protein kinase-mediated response in the fission yeast Schizosaccharomyces pombe pot
... appear to play a key role in the dephosphorylation of the osmotic stress- activated Sty1p [20]. Interestingly, however, the Sty1p activation induced by oxidative stress, although rather rapid, ... during the last years. Atf1p is phosphorylated by Sty1p both in vivo and in vitro under different stress conditions and induces the expression of different stress- response gene...
Ngày tải lên: 08/03/2014, 09:20
Báo cáo y học: "Stress, the stress response system, and fibromyalgia" ppt
... paleness, and Review Biology and therapy of fibromyalgia Stress, the stress response system, and fibromyalgia Manuel Martinez-Lavin National Institute of Cardiology, Juan Badiano 1, 14080 Mexico City, ... the alteration in the circadian rhythm. For many thousands of years, the day and night cycles were harmonious with external cues: light, noise, and activity during...
Ngày tải lên: 09/08/2014, 10:20
Báo cáo y học: "he combined effect of gender and age on post traumatic stress disorder: do men and women show differences in the lifespan distribution of the disorder" potx
... depended on age. They found inconsistent results among respondents from the USA, Mexico, and Poland, where the most distressed werethemiddleaged,theyoung,andtheold,respec- tively. Thus, the age differences ... investigated further in future research in order to develop more thorough explanations for the effect. Summary Thehypothesesmadeforthepresentstudyareverified by the results...
Ngày tải lên: 09/08/2014, 01:21
Báo cáo y học: "Nifedipine decreases sVCAM-1 concentrations and oxidative stress in systemic sclerosis but does not affect the concentrations of vascular endothelial growth factor or its soluble receptor" potx
... endothelial injury. Calcium- channel blockers of the dihydropyridine type have clearly been shown to have an effect on Raynaud's syndrome in SSc and several studies have suggested that they ... endothelium injury in SSc and that VEGF signalling may by impaired in this disease without implication of the sVEGFR-1. Endothelium injury is critical in SSc and is suspected to occur ea...
Ngày tải lên: 09/08/2014, 01:23
Báo cáo y học: " Impaired glucose transporter-1 degradation and increased glucose transport and oxidative stress in response to high glucose in chondrocytes from osteoarthritic versus normal human cartilag" pps
... in the 2-DG uptake assays and the study design, and revised the manuscript. CL participated in the study design. AFM conceived of, designed and coordinated the study, set up some chondrocyte ... similar changes in the synovial fluid glucose concentration, and thus affect glucose delivery to the articular cartilage. Articular chondrocytes are highly glycolytic cells, requ...
Ngày tải lên: 09/08/2014, 14:21