Báo cáo y học: " Immune mechanisms in the pathogenesis of idiopathic inflammatory myopathies" doc

... immunohistochemical localization of inflammatory cells in idiopathic inflammatory myopathies Reference Polymyositis Dermatomyositis Inclusion-body myositis T lymphocytes [9] 53 patients. T lymphocytes were least ... concerning the role of T lymphocytes, B lymphocytes, dendritic cells, and other antigen-presenting cells (APCs) in the pathophysiology of IIMs. T lymphocytes T...

Ngày tải lên: 09/08/2014, 10:20

... purposes) of portacaval shunting, thereby decreasing first pass metabolism; decrease in quantities and affinity of plasma proteins, thereby increasing free-drug levels; increase in volume of distribution ... and lamotrigine. The triad of hypersensi- tivity includes fever, rash and internal organ involvement with onset of symptoms within 1 to 8 weeks of exposure. The freque...

Ngày tải lên: 25/10/2012, 10:51

... be the start of the protein coding domain. Sequence analysis of the 3¢ end cDNA revealed that there is a polyadenylation signal upstream of the poly(A). Analysis of the primary structure of M. ... 2002 Recently, the a subunit of a G protein of the Gq family has been immunolocalized in olfactory sensilla preparations of the silkmoth Antherea pernyi [23]. Using...

Ngày tải lên: 17/03/2014, 23:20

... 4). Effect of handling on BDNF immunoreactivity in the CA4 region of the hippocampusFigure 3 Effect of handling on BDNF immunoreactivity in the CA4 region of the hippocampus. Handling resulted in increased ... evidence indicates that among the serotonin recep- tors, the type 1A are involved in the etiopathogenesis of certain types of depression [23,24] and i...

Ngày tải lên: 08/08/2014, 21:20

... class of inflammatory autoimmune diseases. The presence of exogenous ROS produced by neu- trophils and monocytes may also be contributing to the pathol- ogy of other inflammatory autoimmune diseases. ... fibroblast lines. YM participated in the molecular genetic studies and analysis. EK procured the sam- ples and helped in the analysis of data. GW participated in...

Ngày tải lên: 09/08/2014, 06:23

... of leisure in maintaining or restoring psychological well- being in the presence of arthritis pain warrants further study. Psychosocial approaches to managing arthritis pain Search strategy The ... [16] compared the psychosocial functioning and coping of mothers with chronic pain (including mothers with arthritis) to mothers without pain, with regard to their ratings of pare...

Ngày tải lên: 09/08/2014, 08:23

... be confined to the periphery. The finding of increased areas of punctate hyperalgesia in patients with RA after topical application of capsaicin is in accord with increased excitability of spinal ... also likely to influence activity. The multiplicity of mediators involved provides an opportunity for therapeutic intervention, and many of the commonly used therapeutic s...

Ngày tải lên: 09/08/2014, 10:20

... anti- IL-15 therapy in RA patients [29]. T helper 17 cells There is increasing evidence that IL-17 plays a role in the immunopathology of RA. This proinflammatory cytokine is produced by T helper ... anti-CD20 antibody [2], and the increased interest in the role of autoantibodies in RA. In addition to producing antibodies, proinflammatory cytokines and chemokines, B cells...

Ngày tải lên: 09/08/2014, 10:22

... explained in the following way. The chance of finding a seed-match and of producing a local alignment of significant similarity rises with the length of the frag- ment. Longer fragments, then, ... sequences include only a small proportion of microbes found in nature [14]. Finally, the target genome used for detection of fragments of interest may not be sufficiently...

Ngày tải lên: 09/08/2014, 20:22

... Surgery appears to be preferable as a one arm of multimodality therapy in p-stage III/N2 patients with single or 2 involved lymp h nodes. The optimal incorporation of surgery into the multimodality ... conceived of the study, and drafted the manuscript. MT participated in the study and performed the statistical analysis. SO, YS, YN, HS, HU, and FT participated in the...

Ngày tải lên: 10/08/2014, 09:22