Báo cáo y học: "Knee meniscal extrusion in a largely non-osteoarthritic cohort: association with greater loss of cartilage volume" pps

Báo cáo y học: "Knee meniscal extrusion in a largely non-osteoarthritic cohort: association with greater loss of cartilage volume" pps

Báo cáo y học: "Knee meniscal extrusion in a largely non-osteoarthritic cohort: association with greater loss of cartilage volume" pps

... individ- uals with early radiographic changes had a greater prevalence of medial meniscal extrusion than did those with no radio- graphic changes. Any factors that affect meniscal stability and structure ... that increasing body mass index and bone size, past knee injury, and osteophytes may be causally related to meniscal extrusion. Most importantly, meniscal extrusion...

Ngày tải lên: 09/08/2014, 10:20

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Báo cáo y học: "Gene expression profiling in murine autoimmune arthritis during the initiation and progression of joint inflammation" pps

Báo cáo y học: "Gene expression profiling in murine autoimmune arthritis during the initiation and progression of joint inflammation" pps

... preparation Synthesis and biotinylation of cRNA and hybridization were performed in accordance with the manufacturer's instruc- tions (Affymetrix, Santa Clara, California, USA). In brief, total RNA ... the activation of an anti- inflammatory cascade [51]. Thus, gene expression related to pro-inflammatory and anti-inflammatory events can be detected even before the migration of...

Ngày tải lên: 09/08/2014, 06:22

12 547 0
Báo cáo y học: "Genomic transcriptional profiling identifies a candidate blood biomarker signature for the diagnosis of septicemic melioidosis" ppsx

Báo cáo y học: "Genomic transcriptional profiling identifies a candidate blood biomarker signature for the diagnosis of septicemic melioidosis" ppsx

... forward primer, 5'-gctggaaagctgagagagactt-3', and reverse primer, 5'-cctgat- gcagaccataaaagg-3'; HLA-DMA [GenBank:NM_006120.3 ] forward primer, 5'-agctgcgctgctacagatg-3', ... and DC designed the research, analyzed the data, and wrote the paper. Additional data files The following additional data are available with the online version of this paper: a table c...

Ngày tải lên: 09/08/2014, 20:20

22 395 0
Báo cáo y học: "Emergency intraosseous access in a helicopter emergency medical service: a retrospective study"

Báo cáo y học: "Emergency intraosseous access in a helicopter emergency medical service: a retrospective study"

... patients in emergency situations. As part of their HEMS training programme, intraosseous training was given using man- ual needles, Bone Injection Guns, and EZ-IO® on both manikins and cadavers. All ... resuscitation of criti- cally ill or injured adult and paediatric patients [1,2]. It can be challenging to obtain vascular access, especially in the resuscitation of small children...

Ngày tải lên: 25/10/2012, 10:02

5 560 0
Báo cáo Y học: Extra terminal residues have a profound effect on the folding and solubility of a Plasmodium falciparum sexual stage-specific protein over-expressed in Escherichia coli pptx

Báo cáo Y học: Extra terminal residues have a profound effect on the folding and solubility of a Plasmodium falciparum sexual stage-specific protein over-expressed in Escherichia coli pptx

... Nirbhay Kumar 2 and Amit Sharma 1 1 Malaria Group, International Centre for Genetic Engineering and Biotechnology, Aruna Asaf Ali Marg, New Delhi, India; 2 Department of Molecular Microbiology and ... production of large amounts of soluble native protein has necessarily taken the center-stage. Our findings Fig. 3. SDS/PAGE analysis of Pfg27 B (A) and Pfg27 A (B) cleavage with fact...

Ngày tải lên: 23/03/2014, 21:20

5 436 0
Báo cáo y học: "5HT2A polymorphism His452Tyr in a German Caucasian systemic sclerosis population" ppt

Báo cáo y học: "5HT2A polymorphism His452Tyr in a German Caucasian systemic sclerosis population" ppt

... the Italian population. HapMap data reveal considerable variation of Tyr452 fre- quency among populations. It is especially high within Africans, emphasizing the importance of appropriate case- control ... severity of SSc. In summary, we could not replicate an association of the 5HT 2A His452Tyr polymorphism with SSc in a larger German Letter 5HT 2A polymorphism His452Ty...

Ngày tải lên: 09/08/2014, 01:22

2 277 0
Báo cáo y học: "Complex cytokine effects in a complex autoimmune disease: tumor necrosis factor in systemic lupus erythematosus" potx

Báo cáo y học: "Complex cytokine effects in a complex autoimmune disease: tumor necrosis factor in systemic lupus erythematosus" potx

... rheuma- toid synovial hyperplasia and a clinical benefit of anti-TNF- alpha therapy for RA. Cytokine 2000, 12:281-288. 59. Yamasaki S, Kawakami A, Nakashima T, Nakamura H, Kamachi M, Honda S, Hirai ... may explain why TNF blockade can induce increases in antinuclear antibodies and at the same time rapidly reduce inflammation and prevent inflam- mation-induced damage, also observed in...

Ngày tải lên: 09/08/2014, 01:22

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Báo cáo y học: "κ Increased AP-1 and NF-κB activation and recruitment with the β combination of the proinflammatory cytokines IL-1β, tumor necrosis factor alpha and IL-17 in rheumatoid synoviocyte" ppt

Báo cáo y học: "κ Increased AP-1 and NF-κB activation and recruitment with the β combination of the proinflammatory cytokines IL-1β, tumor necrosis factor alpha and IL-17 in rheumatoid synoviocyte" ppt

... la Polyarthrite. References 1. Asahara H, Fujisawa K, Kobata T, Hasunuma T, Maeda T, Asanuma M, Ogawa N, Inoue H, Sumida T, Nishioka K: Direct evi- dence of high DNA binding activity of transcription factor AP-1 in rheumatoid ... (Leica, Paris, France) coupled to a video camera (Nikon, Champigny, France). The mean green intensity of the nuclear staining was quantified with Lucia ®...

Ngày tải lên: 09/08/2014, 01:23

9 414 0
Báo cáo y học: "roteoglycan 4 downregulation in a sheep meniscectomy model of early osteoarthritis" docx

Báo cáo y học: "roteoglycan 4 downregulation in a sheep meniscectomy model of early osteoarthritis" docx

... joints. A focal decrease in PRG4 in early OA could have a role in the pathogenesis of cartilage degeneration. In the present study we have demonstrated in an animal model that early degeneration ... Australia 2 Department of Endocrinology, Royal Prince Alfred Hospital and Department of Medicine, University of Sydney, Missenden Road, Camperdown, NSW 2050, Australia 3 S...

Ngày tải lên: 09/08/2014, 07:20

6 425 0
Báo cáo y học: "Collagen-induced arthritis in C57BL/6 mice is associated with a robust and sustained T-cell response to type II collagen" pot

Báo cáo y học: "Collagen-induced arthritis in C57BL/6 mice is associated with a robust and sustained T-cell response to type II collagen" pot

... stained with haematoxylin and eosin. In the early stages of CIA, inflammatory infiltrates were found in both the DBA/1 (Figure 2a) and B6 (Figure 2b) joints. However, at late stages of disease, ... (methotrexate), and a nonsteroidal anti-inflammatory drug (indomethacin). Clinical score was assessed, as a measure of spread of disease pro- gression. As expected, dexamethasone...

Ngày tải lên: 09/08/2014, 10:21

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