Báo cáo y học: " Cell therapy for autoimmune diseases" ppt

... the nomenclature for MSC: the International Society for Cellular Therapy position statement. Cytotherapy 2005, 7:393-395. 69. Colter DC, Sekiya I, Prockop DJ: Identification of a subpopula- tion of rapidly ... Switching established type 1 T-helper effector responses to a type 2 Review Cell therapy for autoimmune diseases Francesco Dazzi 1 , Jacob M van Laar 2 , Andrew Cope 1 and...

Ngày tải lên: 09/08/2014, 10:20

... only • Two groups of subjects: Hydrotherapy and home exercise: (24 subjects) home exercise 2× daily and hydrotherapy 2× per week for 6 week Home exercise only: (23 subjects): 2× daily for ... osteoarthritis, osteoarthritic, pain, function, quality of life, exercise, rehabilita- tion, physical therapy, physiotherapy, hydrotherapy, aquatic, strength(ening), resistance, aerobic, endura...

Ngày tải lên: 09/08/2014, 14:22

... technology, without it being necessary to type every DNA variant indi- vidually in an attempt to identify the functional polymor- phism responsible for a disease. Until recently, only a few studies ... haplotype networks that can be defined by a relatively small number of markers. What then should the gene mappers conclude from these apparently disparate results? By defining haplotypes very...

Ngày tải lên: 09/08/2014, 01:21

... resting cells and is expressed only upon activation of the APC. Because only CD86 is expressed on the cell surface early after the Review Multiple functions for CD28 and cytotoxic T lymphocyte antigen-4 during ... apparently only a surrogate marker for T reg cells, and the transcription marker FoxP3 is expressed only intracellularly, prolonged expression of surface CTLA-4 could be a goo...

Ngày tải lên: 09/08/2014, 01:23

... factor family to be differentially expressed in type 1 and type 2 cells. TRAF4 was expressed at a higher level in type 1 cells while TRAF5 was preferentially expressed in type 2 cells. Members ... type 1 and type 2 immune responses [10,11]. Cell- mediated (type 1) immunity is necessary for protection against most intracellular pathogens and, when excessive, can mediate organ- specific aut...

Ngày tải lên: 09/08/2014, 01:21

... genetic synovectomy, and it is the latest development in the tradition of synovectomy, as performed surgically, chemically or by radiation therapy. In RA the fibroblast-like type B synoviocyte is ... apoptotic cell death in the synovium and cytolysis of the synovial lining layer in both arthritis models. An alternative approach for suicide gene therapy is to inhibit cell proliferatio...

Ngày tải lên: 09/08/2014, 01:24

... autoimmunity by inhibiting the induction of cytotoxic T lymphocyte response, which nor- mally suppresses autoreactive B-cells [36]. Infliximab might also act by neutralizing the biological activity of ... antibody-dependent or complement- dependent cellular cytotoxicity of the cells expressing the cytokine [37]. Furthermore, infliximab has been shown to increase the number of apoptotic T lymp...

Ngày tải lên: 09/08/2014, 01:24

... pathogenic isotypes are directed. Moreover, microarray isotype analy- sis may provide insight into both B -cell and T -cell auto- immunity because not only T cells, but also effector B cells, have ... delivery of yeast transformants Colorimetric 6000 Performed in Arrays of yeast expressing fusion [10] transformants; modified expressing yeast open reading frames 384-well proteins yeast two-h...

Ngày tải lên: 09/08/2014, 06:22

... incu- bation at 96°C for 10 minutes, and thermal conditions fol- lowed 40 cycles at 95°C for 10 s, 60°C for 15 s and 72°C for 20 s. For each run, serially diluted cDNA of K562 cells was used as ... factor levels was analyzed using analysis of variance. Statistical analysis was performed using Analyse-it for Microsoft Excel (Leeds, Eng- land, UK). Results The allelic and genotypic...

Ngày tải lên: 09/08/2014, 07:20

... T lymphocyte (CD4) cell count testing is the standard method for determining eligibility for antiretroviral therapy (ART), but is not widely available in sub-Saharan Africa. Total lymphocyte ... marker for the CD4 T lymphocyte criterion for initiating antiretroviral therapy. Aids 2003, 17(6):917-919. 5. Kumarasamy N, Mahajan AP, Flanigan TP, Hemalatha R, Mayer KH, Carpenter CC,...

Ngày tải lên: 10/08/2014, 05:20