Báo cáo y học: " T cells and post menopausal osteoporosis in murine models" doc

... treated with autologous BM transplants develop thymic hypertrophy and a resurgence of thymic T cell output that contributes to the restoration of a wide T cell repertoire [29], although the intensity ... appropriate to classify osteoporosis as an inflammatory, or even an autoimmune condition and certainly new therapeutic ‘immune’ targets will emerge. Competing interests The author d...

Ngày tải lên: 09/08/2014, 10:20

... http://arthritis-research.com/content/5/3/131 134 Conclusion The treatment studies with rituximab have created a new treatment strategy that apparently acts upstream of the current treatment regimens employing cytokine blockage and that may be well ... depletion may seriously compro- mise protective humoral immunity [42]. Other treatment strategies targeting B cells are currently in dev...

Ngày tải lên: 09/08/2014, 01:21

... immunostaining). YS carried out the interpretation of the findings. CI participated in the design of the study and performed the statistical analysis. CH participated in the design of the study and critical ... drafted the manuscript. CL carried out the morphometrical analysis of the study. RC participated in the electron microscopy. YM participated in the protein analysis (wester...

Ngày tải lên: 10/08/2014, 10:20

... patients with longstanding rheumatoid arthritis and osteo- arthritis. Rheumatol Int 2005, 26:63-69. 15. Haynes DR, Crotti TN, Loric M, Bain GI, Atkins GJ, Findlay DM: Osteoprotegerin and receptor ... indicates that they can play similar roles in chronic inflammation. Many of these factors are pivotal in causing tissue destruction, either directly or indirectly. We are still to determi...

Ngày tải lên: 09/08/2014, 10:20

... action to some extent; i.e. stimulating antioxidant enzyme sys- tems and enhancing oxygen delivery to tissues [19]. Although efficacy of OT in sepsis was tested in some experimental settings, ... pretreatment on the systemic inflammatory response during sepsis was also reported [40]. These contradictory findings necessitate studies testing the efficacy of OT after sepsis induction...

Ngày tải lên: 25/10/2012, 11:18

... of the pathology of the disease, therapeutic regimens, and weight gain and inactivity secondary to treatment. The reduction in cardiopulmonary capacity may lead to reductions in quality of ... patients exploited the opportunity, so that questionnaire recalls of physical activity intensity and duration resulted easier. In our study only 10.7% of participants withdrew from th...

Ngày tải lên: 08/08/2014, 16:23

... of these compounds, with the remaining amounts being eliminated in unknown proportions by the exo- crine glands and by the respiratory and gastrointestinal tracts [11,12]. The total amount of ... not for citation purposes) amino acids (especially tyrosine) [23]. Nitrotyrosines were not assessed in the present study, but others have previously detected nitrotyrosine in serum of patie...

Ngày tải lên: 09/08/2014, 08:22

... previous studies have focused on transcription initiation or termina- tion, but not elongation. In this study, we attempt to provide insight into elongation inhibition surrounding translation start and ... II; TSS: tran- scription start site; UTR: untranslated region. Competing interests The authors declare that they have no competing interests. Authors' contributions JKC conceived o...

Ngày tải lên: 09/08/2014, 20:20

... declare that they have no competing inter- ests. Authors' contributions TTB drafted the manuscript and directed the statistical analysis. XX and MJ performed the statistical analysis and helped ... the interpretation of the data. MDW provided administrative and intellectual support for the study. JBM participated in the design of the study, assisted with its execution and pro...

Ngày tải lên: 10/08/2014, 05:21

... Creatinine/P and alkaline phosphatase levels at select time points during treatment and disease Initiation ART vs 2 wks ART Initiation ART vs 4 wks ART Initiation ART vs ART end Initiation ART vs ... (5-fluoro-1-(2R,5S)-[2- (hydroxymethyl)-1,3-oxathiolan-5-yl]cytosine; emtricitabine) and stavudine (d 4T) . Results: In this study, the clinical and biochemical correlates of tubular ne...

Ngày tải lên: 10/08/2014, 05:21