Combining global genome and transcriptome approaches to identify the candidate genes of small-effect quantitative trait loci in collagen-induced arthritis pptx

Combining global genome and transcriptome approaches to identify the candidate genes of small-effect quantitative trait loci in collagen-induced arthritis pptx

Combining global genome and transcriptome approaches to identify the candidate genes of small-effect quantitative trait loci in collagen-induced arthritis pptx

... difficult to identify. Here we present a novel strategy to identify the candidate genes for small-effect quantitative trait loci (QTL) in collagen induced arthritis (CIA) using global genome and transcriptome approaches. ... linked to RA. For five of the eight small-effect QTL the DBA/1 alleles are the arthritis- enhancing alleles, while the FV...

Ngày tải lên: 09/08/2014, 10:20

9 317 0
Understanding Tuberculosis – Global Experiences and Innovative Approaches to the Diagnosis Edited by Pere-Joan Cardona potx

Understanding Tuberculosis – Global Experiences and Innovative Approaches to the Diagnosis Edited by Pere-Joan Cardona potx

... Infections in Trinidad & Tobago and Determination of Drug Susceptibility Profile of Tuberculosis Isolates in the Caribbean 49 and these include the presence of lymphocytopenia and/ or inflammatory ... factor causing additional challenges to the diagnosis of TB; hence, a major contributor to the increased incidence of TB across the world. Infection with...

Ngày tải lên: 31/03/2014, 00:20

562 507 0
Báo cáo khoa học: The use of recombinant protein and RNA interference approaches to study the reproductive functions of a gonad-stimulating hormone from the shrimp Metapenaeus ensis ppt

Báo cáo khoa học: The use of recombinant protein and RNA interference approaches to study the reproductive functions of a gonad-stimulating hormone from the shrimp Metapenaeus ensis ppt

... source for the final synthesis of vitellin. The newly made vitel- logenin is expected to be secreted rapidly into the hemolymph and transported to the ovary for oocyte uptake. To demonstrate that the increase ... assay for molt inhibition [4]. Except for the role of CHH in the increase of glycemia, the use of recombinant protein to study molt-inhibiting func...

Ngày tải lên: 16/03/2014, 05:20

11 546 0
TECHNOLOGIES AND APPROACHES TO REDUCING THE FUEL CONSUMPTION OF MEDIUM- AND HEAVY-DUTY VEHICLES docx

TECHNOLOGIES AND APPROACHES TO REDUCING THE FUEL CONSUMPTION OF MEDIUM- AND HEAVY-DUTY VEHICLES docx

... services of eminent members of appropriate professions in the examination of policy matters pertaining to the health of the public. The Institute acts under the responsibility given to the National ... operating agency of both the Na- tional Academy of Sciences and the National Academy of Engineering in providing services to the government, the...

Ngày tải lên: 22/03/2014, 10:20

251 526 0
Tài liệu Báo cáo khoa học: Single phosphorylation of Tyr304 in the cytoplasmic tail of ephrin B2 confers high-affinity and bifunctional binding to both the SH2 domain of Grb4 and the PDZ domain of the PDZ-RGS3 protein ppt

Tài liệu Báo cáo khoa học: Single phosphorylation of Tyr304 in the cytoplasmic tail of ephrin B2 confers high-affinity and bifunctional binding to both the SH2 domain of Grb4 and the PDZ domain of the PDZ-RGS3 protein ppt

... phosphorylation of Tyr304 in the cytoplasmic tail of ephrin B2 confers high-affinity and bifunctional binding to both the SH2 domain of Grb4 and the PDZ domain of the PDZ-RGS3 protein Zhengding Su, Ping Xu and ... down- stream of the Eph and ephrin molecules appear to lead to the regulation of the cytoskeleton of the interacting cells [1,2,6]. Phos...

Ngày tải lên: 19/02/2014, 12:20

12 551 0
Báo cáo khoa học: Combined use of selective inhibitors and fluorogenic substrates to study the specificity of somatic wild-type angiotensin-converting enzyme docx

Báo cáo khoa học: Combined use of selective inhibitors and fluorogenic substrates to study the specificity of somatic wild-type angiotensin-converting enzyme docx

... mainly inhibit the activity of one active site, allowing the determination of the kinetic parameters of the other active site, free of inhibitor. For each species and each inhibitor, ACE was incubated ... the N-domain, only IC 50 values for inhib- itor binding to the N-domain can be obtained from the inhibition profile. Thus, affinity of the inhibitor for the mou...

Ngày tải lên: 16/03/2014, 13:20

10 499 1
Agent-based and analytical modeling to evaluate the effectiveness of greenbelts potx

Agent-based and analytical modeling to evaluate the effectiveness of greenbelts potx

... that increasing the width of the area to the left of the greenbelt (i.e. increasing g) allows one to decrease the width of the greenbelt while achieving the same delay of sprawl. For instance, to achieve ... be a continuous rectangle from the top of the lattice to the bottom. The width of the landscape, X Size, is increased by the value of w to...

Ngày tải lên: 23/03/2014, 13:20

13 402 0
Báo cáo khoa hoc:" A method to optimize selection on multiple identified quantitative trait loci" docx

Báo cáo khoa hoc:" A method to optimize selection on multiple identified quantitative trait loci" docx

... vector containing the standard normal truncation points corres- ponding to the fractions selected f j,t . The derivative of S j,t with respect to the f j,t can be obtained using the properties of ... Parallel efforts in the search for genes that affect quantitative traits have focused on the identification of genetic markers that are linked to quantitative tr...

Ngày tải lên: 09/08/2014, 18:21

26 205 0
Đề tài " Classical and modular approaches to exponential Diophantine equations I. Fibonacci and Lucas perfect powers " pdf

Đề tài " Classical and modular approaches to exponential Diophantine equations I. Fibonacci and Lucas perfect powers " pdf

... not taken into account in the general result of [10], and, on the other hand, there has been an important improvement, due to Matveev, in the theory of linear forms in logarithms since [10] has ... problem of determining the perfect powers in the Fibonacci and Lucas sequences naturally reduces to the problem of solving the following pair of equations: F...

Ngày tải lên: 06/03/2014, 08:21

51 397 0
Clinical, Research and Treatment Approaches to Affective Disorders Edited by Mario Francisco Juruena potx

Clinical, Research and Treatment Approaches to Affective Disorders Edited by Mario Francisco Juruena potx

... part of the functioning of the brain integrating the paradigm. The interaction of the mind, an explicit functioning of the brain, with other body systems is critical for the maintenance of homeostasis ... widely investigated in studies of major depression and suicide. The innervations of the serotonin system project from the dorsal raphe nucleus to a...

Ngày tải lên: 17/03/2014, 02:20

376 444 0
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