Báo cáo khoa học: "Weak expression of cyclooxygenase-2 is associated with poorer outcome in endemic nasopharyngeal carcinoma: analysis of data rom randomized trial between radiation alone versus concurrent chemo-radiation (SQNP-01)" pdf

... staining; 1–4, weak staining; 5–8, moderate staining; and 9–12, strong staining. For the purpose of statistical analysis, the cohort was grouped into tumors with negli- gible or weak staining ... retrospective analysis of 58 samples from patients, diagnosed with endemic NPC, who had previously been randomized into a trial of radiotherapy (RT) alone versus concurrent c...

Ngày tải lên: 09/08/2014, 10:20

... site of the main adhesine P1 of M. pneumoniae. This is the only other M. pneu- moniae protein, of which the N-terminus of the mature protein was experimentally determined. For this pro- tein, ... labeled within the intact protein at its a-amino group and represents the amino terminal amino acid of P40. The efficiency of this reaction was quite high, as judged from the signal inte...

Ngày tải lên: 19/02/2014, 18:20

... address this question. As shown in Fig. 1B, the distance between the two termini of the inserted Ca 2+ -binding sites in the model structure of the EF-hand of STIM1 is within 15 A ˚ . Accordingly, ... population of the EF-hand motif in STIM1 is occupied by Ca 2+ . Removing the proposed Ca 2+ -coordinating residues in positions 1 and 3 of the EF-hand motif significantly...

Ngày tải lên: 07/03/2014, 00:20

... for Pisum sativum and Synechocystis P-protein with H-protein from Flaveria trinervia, Arabidopsis thaliana or Synechocystis as substrate. H-proteins carrying an N-terminal extension of four amino ... H-protein only by the insertion of two additional alanyl residues near the N-terminus. Kinetic analysis of the these two H-proteins fully con- firmed our findings with the two Flaveria...

Ngày tải lên: 23/03/2014, 04:20

... the stage of disease in 42% of cases, up regulating in 28% and down regulating in 14% of cases [2]. The procedure con- sisted of liver and lymph node biopsies together with splenectomy. In addition ... 5); inadequate (n = 4). The remaining 30 patients proceeded to biopsy without FNAC. FNAC was performed in 18 of 23 patients with cervical lymphaden- opathy but in only...

Ngày tải lên: 09/08/2014, 07:21

... staining was found in both cell lines, showing that PrP Sc is effectively internalized by both cell lines, independent of stimulation and of surface PrP c levels. In addition, both cell lines harboured, ... Role of microglia in neuronal cell death in prion disease. Brain Pathol 8, 449–457. 35 Baker CA, Martin D & Manuelidis L (2002) Microglia from Creutzfeldt–Jakob disease...

Ngày tải lên: 07/03/2014, 05:20

... the stained area of interest as percentage of total tissue area. Biochemical Ab analysis Cortical and cerebellar brain tissues from perfused animals were extracted at a ratio of 1 : 10 (tissue ... animals (n = 4) displaying such behaviors were excluded. Histology and image analysis Mice were anesthetized with 0.4 mL of avertin (25 mgÆmL )1 ) and intracardially perfused with 0....

Ngày tải lên: 23/03/2014, 06:20

... participation of frataxin in delivering iron to heme synthesis is frequently mentioned in the lit- erature, scarce direct evidence exists on the role of this protein in the biogenesis of heme-containing ... Fe–S-containing proteins, a reduction of heme a and concomitantly the cytochrome oxidase activity, suggesting an important role of frataxin in the biogenesis of heme-...

Ngày tải lên: 28/03/2014, 23:20

Ngày tải lên: 07/08/2014, 15:20

... patients with a current remission versus active disease (either active disease with a previous remission or continuously active disease). *Only CRP values of oligoarthritis patients with active disease ... subgroups consisted of too few individuals to permit reliable statistic analysis. Of the 218 remaining patients, 151 had oligoarthritis and 67 had pol- yarthritis. The patie...

Ngày tải lên: 09/08/2014, 10:23