Báo cáo khoa học: "Outcome in recurrent head neck cancer treated with salvage-IMRT" docx

... expected increasing (e.g. ~20%). This data suggest the generous indication for postoperative IMRT in initial situations with estimated RR exceeding ~10–15%. n treated R: number of treated recurrences ... was given (in 27/44 cisplatin (40 mg/m2/w), in 3/44 erbitux (3–6 cycles: 1×400 mg/m2 and 2–5×250 mg/ m2/w; indications: contraindications against cisplatin, intolerance of cisplat...

Ngày tải lên: 09/08/2014, 09:22

... sulfate, changing the binding sites for extracellular growth factors. SULF1 expression has been reported to be decreased in various cancers, including ovarian cancer. We hypot hesized that single nucleotide ... decreased in multiple malignant lineages, and its re-expression is k nown to be associated with decreased signaling of heparin-binding growth factors, cell proliferation, and th...

Ngày tải lên: 10/08/2014, 10:20

... simultaneously integrated boost (SIB) in head and neck cancer patients. Radiat Oncol 2006, 1:7. 2. Feng Y, Kim MHyungjin, et al: Intensity-Modulated Chemoradiotherapy Aiming to Reduce Dysphagia in Patients ... Huguenin P, Beer KT, Allal A, et al: Concomitant Cisplatin Significantly Improves Locoregional Control in Advanced Head and Neck Cancers Treated With Hyperfractionat...

Ngày tải lên: 09/08/2014, 09:20

... associated with increased acute and long term morbidities [1,2]. Increasing effort has been directed toward developing molecular targeted therapies for the treatment of NPC with increasing interest in ... 1–4, weak staining; 5–8, moderate staining; and 9–12, strong staining. For the purpose of statistical analysis, the cohort was grouped into tumors with negli- gible or weak staining...

Ngày tải lên: 09/08/2014, 10:20

... glycan-discriminating proteins. In general, however, the glycan–lectin interaction is relatively weak in comparison with, for example, antigen–anti- body interactions. Thus, once bound to a lectin on ... begin our experiments with cultured cancer cells and cancer tissues obtained by microdissection. Unfortunately, researchers often analyze the serum of patients with advanced can...

Ngày tải lên: 16/02/2014, 08:20

... in 100%, 95% and 70% ethanol and in water for 30 min at room temperature. After rinsing twice for 5 min with PBST (NaCl ⁄ P i contain- ing 0.05% Triton X-100), slides were incubated in blocking solution ... Streptavidin (Invitrogen; 1 : 200) in blocking solution for 1 h. Sections were washed and mounted in Vectashield Mounting medium with 4¢,6-di- amidino-2-phenylindole for nucl...

Ngày tải lên: 18/02/2014, 08:20

... major interaction site for the adenine moiety. In b1, an arginine residue (Ile417 in rPDE2) binds to N1 and a threonine (Ser419 in rPDE2) inter- acts with N7 and the N 6 amino group. The inter- actions ... cGMP binding [13], and, in PDE6, both of the amino acids corresponding to Phe433 ⁄ Asp434 in rPDE2A are required for cGMP binding [14]. Our initial mutations in cyaB1 GAF B al...

Ngày tải lên: 19/02/2014, 02:20

... surface of the protein and makes no obvious stabilizing interactions with other amino acid side- chains, this part of the protein interacts with genomic RNA [33,41,47]. Such interactions probably ... protein and in its interaction with the nucleic acid. Here we investigated how the packing and stability of virus capsids are sensitive to single amino acid substitutions in the coat pr...

Ngày tải lên: 19/02/2014, 12:20

... purposes. In giving a synonym definition, we are making use of a more general idea, namely, that of defining the intra- linguistic meaning of a word in terms of its relations with other words, ... of definition distinguishes the intra-linguistic meaning of a word, as represented by its relations with other words in the vocabulary, from its extra-linguistic meaning or reference...

Ngày tải lên: 19/02/2014, 19:20

... 103060min0 C Fig. 4. Metabolic labeling of rRNA. Pulse-chase labeling with [ 3 H]uracil or with [methyl- 3 H]methionine was performed after incubating Dnop53 ⁄ A-NOP53 and control strains in glucose ... [6,7]. In this study, Nop53p was isolated in a two-hybrid screen as a protein interacting with Nop17p, which is involved in the early steps of pre- rRNA processing [28]. Nop17p a...

Ngày tải lên: 20/02/2014, 01:20