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Báo cáo khoa học: "Acute and late toxicity in prostate cancer patients treated by dose escalated intensity modulated radiation therapy and organ tracking" pps

Báo cáo khoa học:

Báo cáo khoa học: "Acute and late toxicity in prostate cancer patients treated by dose escalated intensity modulated radiation therapy and organ tracking" pps

... AccessResearchAcute and late toxicity in prostate cancer patients treated by dose escalated intensity modulated radiation therapy and organ trackingPirus Ghadjar†, Jacqueline Vock†, Daniel ... patients treated by dose escalated intensity- modulated radiation therapy (IMRT) and organ tracking.Methods: From 06/2004 to 12/2005 39 men were treated by 80 Gy IMRT along with organ tracking. Median ... L, Born EJ, MiniR, Greiner RH, Aebersold DM: Daily organ tracking in intensity- modulated radiotherapy of prostate cancer using an elec-tronic portal imaging device with a dose saving acquisitionmode....
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báo cáo khoa học:

báo cáo khoa học: " Effects of metastasis-associated in colon cancer 1 inhibition by small hairpin RNA on ovarian carcinoma OVCAR-3 cells" pot

... forHGF-induced scattering [15-17]. In colon cancer cells,MAPK signaling could be hyperactive by transfection ofMACC1, and HGF-induced cell scattering mediated by MACC1 could be abrogated by MEK ... downstream signaling cascades, suchas MAPK and PI3K/Akt pathways [14]. MACC1 proteincontains several domains which can participate in MAPKsignaling, and MACC1 can be up-regulated by MAPKpathway ... Cells without b rownstaining scored as 0, with mild brown staining scored a s1, with moderate brown staining scored as 2, with intensebrown staining scored as 3. The final positive scores =positive...
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Báo cáo khoa học:

Báo cáo khoa học: "The evolution of rectal and urinary toxicity and immune response in prostate cancer patients treated with two three-dimensional conformal radiotherapy techniques" ppt

... suffered severe late GI toxicity, and 26 patients (WP-11.21% and PO-16.05%) severe late GU toxicity. In the majority of acute toxicity suffering patients, the diminution of late GI/GU toxicity to ... becoming one of the most significantissues in treatment decision-making, in general, and more so in prostate cancer [1]. Thus late rectal and urinary damage became a major concern in prostate cancer; ... radio- therapy- irradiation of prostate, seminal vesicles, and lymph nodes followed by a prostate boost (116 patients, 59%); and prostate- only (PO) radiotherap y-irradiation of prostate and seminal...
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Báo cáo khoa học:

Báo cáo khoa học: " Prediction of clinical toxicity in locally advanced head and neck cancer patients by radio-induced apoptosis in peripheral blood lymphocytes (PBLs)" ppt

... in predicting radiation induced toxicity. Seventy nine consecutive patients suffering from head and neck cancer, diagnosed and treated in our institution, were included in the study. Toxicity ... the intraindividual and interindivi-dual variations were determined in the four healthydonors and in the 79 patients. Intraindividual variationfor healthy donors was always lower than interindividualvariation ... predicting radiation induced toxicity. MethodsSeventy nine consecutive patients with histological con-firmed cell carcinoma of head and neck, diagnosed and treated in our institution and given inform...
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Tài liệu Báo cáo khoa học: Gene transcription of fgl2 in endothelial cells is controlled by Ets-1 and Oct-1 and requires the presence of both Sp1 and Sp3 pdf

Tài liệu Báo cáo khoa học: Gene transcription of fgl2 in endothelial cells is controlled by Ets-1 and Oct-1 and requires the presence of both Sp1 and Sp3 pdf

... development, and intracellular signaling[10–12]. Thrombin is involved in many biological processes. In addition to its function in blood coagulation and woundhealing, thrombin has diverse functions in ... proteinfamily members all contain fibrinogen-related domains(FRED), known to represent key regions for protein–protein interaction. As a procoagulant, fgl2 is involved in cleaving prothrombin ... spanning 39 bp in the proximal region of thefgl2 promoter. As shown in Fig. 4, mutating nucleotidesfrom )87 to )80 (containing Oct-1), )77 to )71 (containingSp1), )68 to )57 (containing Ets/Stat3)...
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Báo cáo khoa học: Post-translational modifications in the active site region of methyl-coenzyme M reductase from methanogenic and methanotrophic archaea potx

Báo cáo khoa học: Post-translational modifications in the active site region of methyl-coenzyme M reductase from methanogenic and methanotrophic archaea potx

... of the C-terminal glycine in ThiS and MoaD, involved in thiamine biosynthesis and molyb-dopterin biosynthesis, respectively, and for the sulfura-tion of uridine in tRNA to thiouridine can beenvisaged ... phenylalanine instead of atyrosine directly before the thioglycine (Methanoculleusthermophilus and Methanosarcina barkeri) or directlyafter the thioglycine (Methanosarcina barkeri), and analanine instead ... of these modified amino acids, 2-(S)-methylgutamine and 5-(S)-methylarginine, have until now not beenfound in any other protein. 1-N-Methylhistidine ¼ 3-methylhistidineaccording to IUPAC nomenclature.1Methanogenic...
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Báo cáo khoa học: Vitamin D stimulates apoptosis in gastric cancer cells in synergy with trichostatin A ⁄sodium butyrate-induced and 5-aza-2¢-deoxycytidine-induced PTEN upregulation ppt

Báo cáo khoa học: Vitamin D stimulates apoptosis in gastric cancer cells in synergy with trichostatin A ⁄sodium butyrate-induced and 5-aza-2¢-deoxycytidine-induced PTEN upregulation ppt

... that VD3 could induce differentia-tion and cell cycle arrest in a number of malignantmelanoma cells, including those in myeloid leukemia, and breast, prostate, colon, skin and brain cancer [4–8].Phosphatase ... 989Vitamin D promoted the apoptosis induced by 5-AzaWe then investigated the effect of PTEN on the apop-tosis induced by DNA methylation and vitamin D in gastric cancer cells. We treated HGC-27 ... Vitamin D stimulates apoptosis in gastric cancer cells in synergy with trichostatin A⁄sodium butyrate-induced and 5-aza-2¢-deoxycytidine-induced PTEN upregulationLina Pan1,*, Ammar...
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Báo cáo khoa học:

Báo cáo khoa học: " Prediction of clinical toxicity in localized cervical carcinoma by radio-induced apoptosis study in peripheral blood lymphocytes (PBLs)" pot

... Ninety four consecutive patients suffering from cervical carcinoma, diagnosed and treated in our institution, and four healthy controls were included in the study. Toxicity wasevaluated using ... annexin V binding buffer. Cells were incubated with 4μl of annexin V-FITC and 10 μl of propidium iodide (PI)for 15 minutes at room temperature in the dark. Finally,400 μl of 1× annexin V Binding ... lymphocytes were isolated and irradiated at0, 1, 2 and 8 Gy during 24, 48 and 72 hours. Apoptosis was measured by flow cytometry usingannexin V/propidium iodide to determine early and late apoptosis....
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Tài liệu Báo cáo khoa học: The calcium-induced switch in the troponin complex probed by fluorescent mutants of troponin I doc

Tài liệu Báo cáo khoa học: The calcium-induced switch in the troponin complex probed by fluorescent mutants of troponin I doc

... domains connected by an a-helixandeachdomainhastwoCa2+-binding sites (EF-handmotifs) [4]. The Ca2+-binding properties of isolated TnC arewell known. Sites III and IV in the C-domain (carboxyterminal) ... naturally occurringfluorescent amino acids, tyrosine or tryptophan, or the useof proteins labeled with extrinsic attached probes to analyzeligand binding, protein–protein interaction and foldingpathways ... & Hodges, R.S. (1997) Mapping of asecond actin-tropomyosin and a second troponin C binding siteswithin the C terminus of troponin I, and their importance in theCa2+-dependent regulation...
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Báo cáo khoa học: Novel suppression mechanism operating in early phase of adipogenesis by positive feedback loop for enhancement of cyclooxygenase-2 expression through prostaglandin F2a receptor mediated activation of MEK⁄ ERK-CREB cascade doc

Báo cáo khoa học: Novel suppression mechanism operating in early phase of adipogenesis by positive feedback loop for enhancement of cyclooxygenase-2 expression through prostaglandin F2a receptor mediated activation of MEK⁄ ERK-CREB cascade doc

... G-protein-coupled receptor; and this binding activates thedownstream signaling pathways including the Gqheterotrimeric G protein, and then further increasesthe intracellular calcium level and ... with an MEK inhibi-tor, PD98059; a PLC inhibitor, U73122; a PKCinhibitor, bisindolylmaleimide I; and a general COXinhibitor, indomethacin, or a selective COX-2 inhibi-tor, NS-398, in the presence ... obtained from the Human ScienceResearch Resources Bank (Osaka, Japan), cultured in DMEM (Sigma, St Louis, MO, USA) containing 10%(v ⁄ v) fetal bovine serum and antibiotics, and maintained in a...
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