Báo cáo khoa học: "Reirradiation of recurrent breast cancer with and without concurrent chemotherapy" ppt

... heterogeneous group of 29 patients suffering from recurrent breast cancer after previous radiotherapy. Reirradiation was given with cumulative total doses of 80.4 to 126 Gy applied with or without concurrent ... radiotherapy with or without concurrent 5-FU/ capecitabine chemotherapy was given for operable and non-operable recurrences. Methods Since 2003 we offer pati...

Ngày tải lên: 09/08/2014, 09:22

... presence of an adapter introduced to the N-terminus of the protein (see Materials and Methods). Consistent with the inhibition of Ras activation by N17 H-Ras, phosphorylation of Erk1 and 2 proteins ... nucleotide binding and effector loop domains, providing a basis for the ability of Ras proteins to interact with a common set of activators and effectors and to share...

Ngày tải lên: 10/08/2014, 22:20

... 66% in cortical bone at 4 weeks, which compares well with values of 60% and 48% previously reported for a porous beaded coating with and without a 50 μmHAcoatingat4 weeks in an ovine model [10]. In ... Access Osseointegration of porous titanium implants with and without electrochemically deposited DCPD coating in an ovine model Dong Chen 1 , Nicky Bertollo 1 , Abe Lau 1 ,...

Ngày tải lên: 20/06/2014, 07:20

... promising marker of such kind. This paper analyses the serum levels of FA-2 in different stages of breast cancer and examines its role as a marker of bone metabolism in metastatic breast cancer. Methods Patients Blood ... report of its role as a marker of bone metabolism in metastatic breast cancer. Methods: Serum FA-2 concentrations were measured by radioimmunoassa...

Ngày tải lên: 09/08/2014, 03:21

... stereotactic radiosurgery, or external beam radiotherapy with or without chemotherapy and with or without prior debulking surgery. Evidently, bra- chytherapy and stereotactic radiosurgery are attractive options ... 1-year survival rate and MST for patients with a second primary were 54% and 19.8 months, respectively compared with 38% and 7.7 months, respectively for pati...

Ngày tải lên: 09/08/2014, 09:21

... positions of the ribose and base of the second nucleotide. In all cases, the base of the second nucleotide interacted with the Asp66–Thr69 loop and with His86 (Fig. 4B). The majority of the five ... complex, O2¢ and O3¢ form hydrogen bonds with OE1 of Glu56 and NE2 of His86, respectively. Arg67 and Arg71 interact with the oxygens of the phosphate group, and si...

Ngày tải lên: 18/02/2014, 11:20

... purposes. A standard curve was constructed with 3.125 lgÆmL )1 , 6.250 lgÆmL )1 ,12.5lgÆmL )1 and 25 lgÆmL )1 of ATP. The absorbance of the samples was measured with a UV detec- tor at 254 nm, and the ... reducing the activity of i-mtNOS, increased the activity of the ETC complexes over the control values, and normalized the levels of LPO. Reducing the levels of free rad...

Ngày tải lên: 19/02/2014, 00:20

... NP and MP and between HP and HPO in accordance with the similar shapes and sizes between NP and MP and between HP and HPO. The different K d values are proportional to the different values of ... Fluorescence traces for NP, MP and HPO were obtained with an excitation wavelength of 360 nm and a filter with a cutoff of 395 nm for emission. Mechanism and kinetics...

Ngày tải lên: 19/02/2014, 00:20

... induced by ligands on C-LytA monitored by near-UV CD with no ligand added (—) and upon addition of ligands: s, d, 2.5 and 20 m M choline; n, m, 2.5 mM and 20 mM atropine; h, j), 2.5 m M and 20 mM ... cuvette and a protein concentration of 19 lm. Tryptophan emission spectra were obtained using an excitation wavelength of 280 nm, with excitation and emission slits of 3 n...

Ngày tải lên: 19/02/2014, 05:20

... interac- tions of the SSB and RPA proteins with ssDNA [23,24]. The Rad51-Tyr232 side chain could thus stack with DNA bases for its interaction with DNA. A reduction in the tyrosine fluorescence intensity of ... from that of RecA. His163 is the only residue with a ring structure similar to that of tyrosine in the L1 loop of RecA. A chemical interference analysis revealed the...

Ngày tải lên: 19/02/2014, 06:20