Báo cáo khoa học: "Gemcitabine/cisplatin versus 5-fluorouracil/ mitomycin C chemoradiotherapy in locally advanced pancreatic cancer: a retrospective analysis of 93 patients" pptx

... show the critical role of the last amino acids in the C-terminus of MaL. Deletion of the four last amino acids strongly reduced the expression of the protein in T. reesei and S. cerevisiae. Further- more, ... preventing binding of oxygen. We analyzed the azide inhibition and determined the inhibition constants for sodium azide, in order to see the e...

Ngày tải lên: 16/03/2014, 00:20

... identify their target in the C-domain using peptide mapping. T hus the inhibitory effect may be due to interference with other reactive residues in NRPS modules like the thiol g roup of the 4 Â-phosphopantethein-moiety ... bound in the binding poc ket o f a nother e nzyme molecule within the active homomultimer. This could explain the distance in sequence homology...

Ngày tải lên: 17/03/2014, 11:20

... C-terminal domains in these types of proteins [10]. Together, these observations suggested that the opposing activities of the two domains may be separated by a third central domain, and that complete AT ... showed that the two similar but chemically distinct reactions are carried out by separate domains within adenylyltransferase. The N-terminal domain car...

Ngày tải lên: 30/03/2014, 08:20

... terms of water storage (in mm per profile). The spatial variability of &thetas; in the forest floor is characterized by an annual mean coefficient of variance of the ... water in the plant-available water potential range, and iii) a marked temporal variability of the water retention capacity. A one-dimensional water flu...

Ngày tải lên: 09/08/2014, 04:20

... Access Sensorineural hearing loss after concurrent chemoradiotherapy in nasopharyngeal cancer patients Janjira Petsuksiri 1* , Achariyaporn Sermsree 1,2 , Kullathorn Thephamongkhol 1 , Phawin Keskool 3 , ... Sensorineural hearing loss after radiotherapy and chemoradiotherapy: a single, blinded, randomized study. J Clin Oncol 2006, 24(12):1904-1909. 21. Skinner R, Pearso...

Ngày tải lên: 09/08/2014, 09:20

... Brunner et al.: Gemcitabine/cisplatin versus 5- fluorouracil /mitomycin C chemoradiotherapy in locally advanced pancreatic cancer: a retrospective analysis of 93 patients. Radiation Oncology 2011 6:88. Submit ... J, Chen YX, Xie WF, Lin Y: Gemcitabine in the chemoradiotherapy for locally advanced pancreatic cancer: A meta- analysis. Radiother Oncol 20...

Ngày tải lên: 09/08/2014, 09:20

... RESEARCH Open Access Neoadjuvant capecitabine, radiotherapy, and bevacizumab (CRAB) in locally advanced rectal cancer: results of an open-label phase II study Vaneja Velenik 1* , Janja Ocvirk 1 , ... safety and efficacy of bevacizumab in combination with che- motherapy and radiation in the neoadjuvant setting [30-34]. In this study we explor...

Ngày tải lên: 09/08/2014, 09:21

... patients with acute toxicity and without it. Those genes were gathered in 4 significant pathways. We could not identify a set of genes that segregates patients with and without late toxicity. In conclusion, ... NA, Haveman J, Klein B, Turesson I, Vrieling H, Giphart-Gassler M: Analysis of gene expression using gene sets discriminates cancer patients with and witho...

Ngày tải lên: 09/08/2014, 09:22

... response (according to the attending physician, based on an increase in the breast tumor and/or pathologic axillary lymph node diameters ≥50%) after completion of anthra- cycline-containing neoadjuvant chemotherapy, ... radiosensitizing effects in combination with drugs acting through modulation of membrane associated events involved in apoptosis induc- tion and increasing oxidativ...

Ngày tải lên: 09/08/2014, 10:20

... Oncology Open Access Research IMRT using simultaneously integrated boost (SIB) in head and neck cancer patients GStuder* 1 , PU Huguenin 1 , JB Davis 2 , G Kunz 2 , UM Lütolf 1 and C Glanzmann 1 Address: ... preservation with IMRT is proven for salivary function. There is still only limited experience with IMRT using simultaneously integrated boost (SIB...

Ngày tải lên: 09/08/2014, 10:20

... signal-regulated kinases: association with epidermal growth factor receptor/ transforming growth factor alpha expression in head and neck squamous carci- noma and inhibition by anti -epidermal growth factor ... Access Review The epidermal growth factor receptor (EGFR) in head and neck cancer: its role and treatment implications Michel...

Ngày tải lên: 09/08/2014, 10:20

... 8:108. doi:10.1186/1752-1947-5-396 Cite this article as: Nthumba: Squamous cell carcinoma (Marjolin’s ulcer) in an orocutaneous fistula of a large mandibular ameloblastoma: a case report. Journal of Medical Case Reports 2011 ... lesions: Part II. Masses and neoplasia. Am Fam Physician 2007, 75:509-512. 6. Hamakawa H, Kayahara H, Sumida T, Tanioka H: Mandib...

Ngày tải lên: 10/08/2014, 23:20

... 4:411 http://www.jmedicalcasereports.com/content/4/1/411 Page 2 of 3 CAS E RE P O R T Open Access Twin reversed arterial perfusion (TRAP) sequence in association with VACTERL association: a case report Sharan Athwal * , Katherine Millard, Kokila Lakhoo Abstract Introduction: ... a case of a monochorionic twin gestation with TRAP sequence in which the sur...

Ngày tải lên: 11/08/2014, 02:22

... 11:22 http://www.biomedcentral.com/1471-2229/11/22 Page 4 of 8 RESEARCH ARTIC LE Open Access Nickel and low CO 2 -controlled motility in Chlamydomonas through complementation of a paralyzed flagella mutant with chemically regulated promoters Paola ... biological activity at low concentrations. Background Chlamydomonas reinhardtii is a unicellular green...

Ngày tải lên: 11/08/2014, 11:21

... nuclear receptor family gene NR5A2 and a non-genic region on chromosome 13q22.1. â 2010 BioMed Central Ltd ABO blood group and other genetic variants associated with pancreatic cancer Anne Marie Lennon 1 , ... augmenting and refining genome- wide association signals. Nat Rev Genet 2009, 10:318-329. doi:10.1186/gm160 Cite this article as: Lennon AM, et al.: ABO blood...

Ngày tải lên: 11/08/2014, 12:20