... volumereceiving a specific dose of 10,12,14,16 and 18 Gy (V10Gy-V1 8 Gy), site of tumor, conformality index [30 ], and homogeneity index. Prognostic factors for treatment outcome and SRS-related complications ... risk of radionecrosis of 38.4% at 2 years in 62 patients with intraparenchymal lesions, with an incidence of events of 0% for volumes covered by the 10 Gy isodose-line≤10 cm3 and 23.7% for volumes ... design, analysis and interpretation of data, and helped to draft the manuscript. EC and MFOperformed the statistical analysis and participated in acquisition and analysis of data. AB and RME critically...