Báo cáo khoa học: "Postmastectomy irradiation in breast in breast cancer patients with T1-2 and 1-3 positive axillary lymph nodes: Is there a role for radiation therapy" ppsx

... nodes remains uncertain and is being examined in a rando- mized clinical trial”. Many surgeons and radiation oncol- ogist are not recommending PMRT to 1-3 axillary lymph node positive patients with a ... breast cancers. Cancer 1981, 48:1863-1872. doi:10.1186/1748-717X-6-28 Cite this article as: Cosar et al.: Postmastectomy irradiation in breast in breast...

Ngày tải lên: 09/08/2014, 09:20

... spe- cificities, is considered for arginase and agmatinase [20]. Such substrate discrimination is particularly important for mammalian arginase II and agmatinase, as both enzymes are mitochondrial and functionally different ... rely mainly in substituents at C -a. This has been, in fact, demonstrated for arginase [38,39] and the same may be safely deduced for agma- tin...

Ngày tải lên: 20/02/2014, 02:21

... 2007) doi:10.1111/j.1742-4658.2007.06008.x Saporin is a type I ribosome-inactivating protein that is often appended with a cell-binding domain to specifically target and kill cancer cells. Uroki- nase plasminogen activator (uPA)-saporin, ... (uPA)-saporin, for example, is an anticancer toxin that consists of a chemical conjugate between the human uPA and native saporin. B...

Ngày tải lên: 07/03/2014, 05:20

... 84; range 2-140 months) after initial treatment of patients with breast cancer via regular visit (annually) for discovering the LRR. In addition to routine clinical examination, disease assessment ... following lumpectomy and axillary dissection for node-negative breast cancer. J Natl Cancer Inst 1992, 84(9):683-689. 22. Bloom HJ, Richardson WW: Histological grading...

Ngày tải lên: 09/08/2014, 03:21

... Oncoplastic breast conserving surgery. Breast cancer and macromastia treated using a mammaplasty technique .A 58-year-old woman with large breasts who presented with an invasive small ductal carcinoma ... Hospital “Marqués de Valdecilla”, Avda Valdecilla s/n, 39008 Santander, Cantabria, Spain. 3 Breast Cancer Unit, University of Cantabria, Hospital “Marqués de Valdecilla”,...

Ngày tải lên: 09/08/2014, 03:22

... Varian Medical Systems, Palo Alto, California, USA). Tangent fields were set up for each patient using standard medial (patient midline) and lateral (mid -axillary line) borders with appropriate ... not for citation purposes) Background Accelerated partial breast irradiation (APBI) is increas- ingly being used as an alternative to whole breast irradia- tion following wide loc...

Ngày tải lên: 09/08/2014, 09:22

... RNA structures, which is measurable in strand displacement assays, and may additionally accelerate annealing. The hypothesis that RNA chaperones and annealers inter- act with their targets in a ... complementary pairs (A U and GÆC), and because, within RNA molecules, guanosine bases can pair with uridine bases without disrupting helical struc- tures, a single RNA sequenc...

Ngày tải lên: 14/02/2014, 19:20

... cytometry. Preparation and analysis of DNA and protein extracts After the appropriate treatment, cellular DNA was isolated from 3 · 10 6 cells per sample, and analyzed for internucleo- lar fragmentation by agarose ... and phospho-eIF 2a (#9721) were from Cell Signaling. Horse- radish peroxidase-conjugated antibody against caspase-3 (#610325) was from BD Pharmigen, and antibody ag...

Ngày tải lên: 14/02/2014, 22:20

... 7p12-13 and codes for a 170kDa receptor tyrosine kinase. All ERBB proteins have four functional domains: an extracellular ligand-binding domain; a transmembrane domain; an intracellular tyrosine kinase ... kinase domain; and a C-terminal regulatory domain [2]. The extracellular domain is subdivided further into four domains. The tyrosine kinase domain consists of an N-lobe and...

Ngày tải lên: 16/02/2014, 09:20

... phase II and translational study of cetuximab in metastatic colorectal carcinoma refractory to irinotecan, oxaliplatin, and fluoropyrimidines. J Clin Oncol 24, 4914–4921. 3 Khambata-Ford S, Garrett ... Inoue A, Hagiwara K, Sunaga N, Yanagitani N, Hida T et al. (2009) Combined Survival Analysis of Prospective Clinical Trials of Gefitinib for Non-Small Cell Lung Cancer with EGFR Muta...

Ngày tải lên: 16/02/2014, 09:20