Báo cáo khoa học: "Acute toxicity of second generation HIV protease-inhibitors in combination with radiotherapy: a retrospective case series" pptx

... treatment of HIV, antiretroviral therapy (ART). There are currently ten PIs available; in chrono- logical order of FDA approval, saquinavir, ritonavir, indinavir, nelfinavir, lopinavir, atazanavir, ... Euhus DA, Place RJ, Huber PJ, Simmang CL: Outcome of HIV- infected patients with invasive squamous-cell carcinoma of the anal canal in the era of highly active antiretroviral...

Ngày tải lên: 09/08/2014, 09:20

... Zoom -in view of the interactions of papain with loop L6 of chagasin and loop L2 of cysta- tin B. (C) Zoom -in view of the interactions of papain with loop L4 of chagasin and the N-terminal segment ... side-chain carbonyl Od1 atom of N64e forms a water-mediated contact with the main-chain N atom of G68, and the main-chain nitrogen of G66 of chagasin forms a w...

Ngày tải lên: 16/03/2014, 04:20

... annotated as Rpa1, lacked the N-terminal domain (data not shown) that in other eukaryotes is involved only in Rpa–protein interactions and has no function in binding DNA [ 45]. In addition, at ... 5¢-GTTAGGGTTAGGGTTAGG-3¢ Tel6-Rev 5¢- CCTAACCCTAACCCTAAC-3¢ Tel6RNA 5¢- GUUAGGGUUAGGGUUAGG-3¢ Tet-tel 5¢- GTTGGGGTTGGGGTTGG-3¢ T3 5¢- AATTAACCCTCACTAAAGGG-3¢ T7 5¢- GTAATACGACTCACTATAGGG-3¢...

Ngày tải lên: 23/03/2014, 13:20

... bOBP and pOBP) w ere incubated withafixedamountofAMA(3l M ) and increasing concentrations of odorants (0.39–50 l M ). The chasing of AMA bound to OBP was followed a s a decay of t he emission of ... Produzioni Animali, Biotecnologie Veterinarie, Qualita ` e Sicurezza degli Alimenti, Universita ` di Parma, Parma, Italy The structure of bovine odorant-binding protein (bOBP) reveale...

Ngày tải lên: 30/03/2014, 15:20

... of melittin and KAL, but does not seem to a ect the strong interfacial binding of magainin. For example, at peptide concentrations of 2 l M , melittin induced a CR of % 20% in Ole 2 PtdSer/PamOle- PtdCho/PDA ... titanium particles. Ultracentrifugation binding assay An ultracentrifugation binding assay was carried out for evaluating peptide affinities to the vesicles (partition coe...

Ngày tải lên: 30/03/2014, 20:20

... the clinical analysis of the dataset. CH and AvD performed the histopathological and molecular analysis. SC, JD, CH and AA analyszed the prognostic relevance of the molecular data. SC and CH ... such as cisplatinum might inactivate or attenuate MGMT-status thus influencing the clinical outcome when combined with alkylating chemotherapies. An important differential explanation is the...

Ngày tải lên: 09/08/2014, 09:21

... collaboration between physiotherapists and occupational therapists, and involvement of t herapy assistants. Role sharing and expansion are examples of organisational interventions [35]. A more in- depth examination ... following task-specific training [ 6]. One of these trials reported increased walking capacity following four weeks of treadmill training and overground walking prac...

Ngày tải lên: 10/08/2014, 10:23

... phosphati- dylinositol 3-kinase in the activation of glycogen synthase and mitogen-activated protein kinase by insulin in rat adipocytes: comparison of insulin and protein kinase C modulators. ... a variety of conclusions. In our laboratory, we are interested in the relationship between activation of two major signaling pathways: one initiated by p21ras proteins leading to a...

Ngày tải lên: 30/03/2014, 20:20

... (Merck &Co.,Inc.,WhitehouseStation,NJ,USA),ahistone deacetylase inhibitor, in combination with pelvic pallia- tive radiotherapy for advanced gastrointestinal carci- noma [5], and have experienced methodological limitations in determining maximum-tolerated ... typically in normal tissues with a hierarchical proliferative structure, such as the muco- sal lining of the gastro...

Ngày tải lên: 09/08/2014, 09:20

... K m values increase from G1P over PhyK to AppA by a factor of  2200. The confor- mational changes of AppA upon substrate binding facilitate a faster turnover of phytate and are in line with a higher ... the native data with a resolution of 1.68 A ˚ . Iterative cycles of model building and refinement with arp ⁄ warp, refmac and o resulted in a final model contain...

Ngày tải lên: 16/02/2014, 09:20