Báo cáo khoa học: "The Akt-inhibitor Erufosine induces apoptotic cell death in prostate cancer cells and increases the short term effects of ionizing radiation" pot

... 5:108 http://www.ro-journal.com/content/5/1/108 Page 9 of 12 RESEA R C H Open Access The Akt-inhibitor Erufosine induces apoptotic cell death in prostate cancer cells and increases the short term effects of ionizing radiation Justine Rudner 1 , ... this article as: Rudner et al.: The Akt-inhibitor Erufosine induces apoptotic cell death in...

Ngày tải lên: 09/08/2014, 09:20

... [28]; labelling of the isoform containing this mutation was there- fore assigned the value of 100% after 300 min. Both the cysteine-less and G324C isoforms were incubated with 10 lm probe for 300 min and ... to the other isoforms. The extent of labelling for each single-cyste- ine mutant was therefore determined by comparison with G324C. In order to calculate the speci...

Ngày tải lên: 06/03/2014, 22:21

... number and ratio- nality for nominals in our corpus. In terms of gen- der, the M value seems to be twice as common as F both in form and function. In 91.4% of all nomi- nals, function and form ... Nizar Habash, and Owen Rambow. 2011. Improving Arabic Dependency Parsing with Form- based and Functional Morphological Features. In Pro- ceedings of the 49th Annual Mee...

Ngày tải lên: 07/03/2014, 22:20

... chemoradiotherapy in technically operable IIa-III esophageal carcinoma is still unresolved. Findings We have read with interest the report from Hurmuzlu and coll [1] on the outcome of induction therapy ... treatment. In this scenario of substantial absence of a large base of methodologically correct evidence and agreed guidelines we consider the results from [1] of sig...

Ngày tải lên: 09/08/2014, 01:24

... (j)arethemeanvaluesof four replicates, and in the Northern analysis (h)themeanvaluesof two replicates. (B) The time sensitivity of GPR30 mRNA expression correlated with the beginning of progestin-induced ... GPR30, the expression of which correlated with growth inhibition. The potential importance of the G-proteins in progestin-mediated signaling is also highligh- te...

Ngày tải lên: 24/03/2014, 00:21

... solution of 1 lgÆlL )1 in meth- anol) was added to the cell suspension, and the cells were incubated for 2 h at 28 °C in the dark. Aliquots containing approximately 10 7 cells were harvested, and ... by the luminescence spectrum of the aequorin-expressing cells (Fig. 6A). This observation suggested that, as in the response to H 2 O 2 , cells utilize Ca 2+ -...

Ngày tải lên: 15/03/2014, 23:20

... was observed in the HSS-expressing cells treated with CCCP as compared with the vector-transfected cells and cells expressing mutant HSS. Furthermore, silencing of HSS expression using small interfering ... wild-type cells (Fig. 1A). Protein expression of HSS in the three cell lines (untransfected cells, vector-transfected cells, and HSS-expressing cells) was de...

Ngày tải lên: 16/02/2014, 09:20

... a solution of the protein. Typically an initial injection of 2 lL copper chelate solution was followed by a further 29 injections of 4 lL of Cu(II) into the protein in the sample cell stirred at ... human cystatins. Further support for the premise that the C-terminus could be the copper binding domain comes from stud- ies of the P79S mutant, which differs from the...

Ngày tải lên: 19/02/2014, 06:20

... understanding of system capa- bilities. Of the remaining 66% of inputs (2166) which were within the functionality of the system, 68% were in grammar. On the within functionality portion of the ... completing the same two sets of scenarios and then freely interacting with each system. For counterbalancing purposes, half of the subjects used the tablet a...

Ngày tải lên: 20/02/2014, 12:20

... contain mutated TP53). Further development of the assay to address these shortcomings offers the possibility of wider application of the assay to investigate some of the many outstanding uncertainties ... G, Invidia L, Vannini I, Rossi M, Marzi E et al. (2004) The different apoptotic potential of the p53 codon 72 alleles increases with age and modulates in vivo i...

Ngày tải lên: 06/03/2014, 11:20