Báo cáo khoa học: "The role of adjuvant pelvic radiotherapy in rectal cancer with synchronous liver metastasis: a retrospective study" doc

... that pel vic irradiation has a palliative role in treating rectal cancer liver metastasis [18]. Eightypatients with synchronous distant metastases from rectal cancer were treated with chemoradiation ... liver metastases are found in 20% to30% of colorectal cancer patients at initial diagnosis [3]. In rectal cancer patients with liver metastasis, conser-vative management including diverting colostomyresulted ... clinical fac-tors including patients’ age, Duke stage, initial CEAlevel, lateral resection margin, liver metastasis stage,local treatment for liver metastasis, an d adjuvant pelvic RT, in order...

Báo cáo khoa học: The role of interface framework residues in determining antibody VH ⁄ VL interaction strength and antigen-binding afﬁnity pptx

... (5¢-GTCCTCGCAACTGCGGCCCAGCCGGCCATGGCCSARGTNMAGCTGSAGSAGTCWGG-3¢) and H10VHframe2 (5¢-ACCACTGTAGCTTACGTACCCCAWSYACTCCAGACSKTTACCTGGARRTTKACGAAYCCAGCTCCAATAATCACTGGT-3¢) with pKST2(HyHEL-10) as a template. Also, ... biosensor as a several-fold increase in antigen-binding afﬁnity owing to an increased associationrate, while a slight decrease was observed for the single-chain variableregion.AbbreviationsFR2, ... compare the antigen-bind-ing afﬁnity at this titer, and to use the ratio of speciﬁcabsorbance minus background absorbance at this titeragainst that of wild-type as an index of the relativeafﬁnity...

Báo cáo khoa học: "The Role of Lexico-Semantic Feedback in Open-Domain Textual Question-Answering" ppt

... 1995.Dan Moldovan, Sanda Harabagiu, Marius Pas¸ca, RadaMihalcea, Richard Goodrum, Roxana Gˆırju and VasileRus. The Structure and Performance of an Open-DomainQuestion Answering System. Proceedings ... have all the prop-erties of lava, the following question semanticThe Role of Lexico-Semantic Feedback in Open-Domain TextualQuestion-AnsweringSanda Harabagiu, Dan MoldovanMarius Pas¸ca, Rada ... synsetscontaining the original keyword; and (b) have a chain of WordNet relations or bigram relationsthat connect it to the original keyword. Theserelations can be translated in axiomatic form andthus...

Báo cáo khoa học: The role of glucose 6-phosphate in mediating the effects of glucokinase overexpression on hepatic glucose metabolism pdf

... dissociation of glucokinase from GKRP areassociated with a parallel increase in the cell content of Glc6P, conﬁrming the regulatory role of GKRP onglucokinase activity [8]. Recent studies have ... by altering its subcellularlocation [10]. In the liver cell, Glc6P is an intermediate of variousmetabolic pathways and a substrate for glucose6-phosphatase [12]. It is also a key regulator of ... glu-cokinase with a rabbit IgG against human glucokinase:318–405 (H88, sc-7908; Santa Cruz) and ﬂuorescein isothiocya-nate (FITC)-labelled anti-rabbit IgG [6]. Imaging for FITCﬂuorescence was...

Báo cáo khoa học: The role of cytochrome P450 monooxygenases in microbial fatty acid metabolism pdf

... forward as a candidate forx-oxidation in the cyanobacteria Anabaena variabilis.Although CYP110 is induced by alkanes such as hex-adecane, CYP110 does not participate in alkane degra-dation; ... role of P450 in bacterial a- oxidation of phytanic acid.Fatty acid hydroxylating P450sinvolved in secondary metabolitesynthesisBiosurfactantsBiosurfactants are surface-active compounds capable of ... prokaryoticP450s are cytosolic and communicate with two sepa-rate redox partners: a NAD(P)H-binding and FAD-containing reductase and a ferrodoxin or ﬂavodoxinthat transfers the electrons from the reductase...

Báo cáo khóa học: The role of N-linked glycosylation in the protection of human and bovine lactoferrin against tryptic proteolysis pdf

... neutrophils(reviewed in [2]). LF is involved in nonspeciﬁc host defenceagainst infection and severe in ammation, most notably atmucosal surfaces such as those of the gastrointestinal tract[2]. Antimicrobial activities ... iron-binding site. Biochem.J. 266, 575–581.26. Shimazaki, K., Tanaka, T., Kon, H., Oota, K., Kawaguchi, A. ,Maki, Y. & Sato, T. (1993) Separation and characterization of theC-terminal half ... vitro and in vivo antigenicity, iron-binding and release and binding to several ligands [21]. Theonly indication for a difference in conformation betweenrhLFcDNAand natural hLF was the increased...

Báo cáo khoa học: The role of ADAM10 and ADAM17 in the ectodomain shedding of angiotensin converting enzyme and the amyloid precursor protein ppt

... APMAinducing the shedding and/or activation of a proteasecapable of rapidly degrading sAPPa,tosAPPa beingrapidly taken up by the APMA-stimulated cells, theconﬂuency state of the cells or an artefact ... the lack of effect of APMA on the a- secretase cleavage of APP in the human SH-SY5Y cellsagain underlines that TACE is not critically involved in APP shedding, at least in this cell line.Although ... However, ASO knock-down of TACEfailed to reduce the APMA-induced shedding of ACEindicating that this ADAM is not involved. ASO knock-down also revealed that ADAM10 was not involved in the APMA induced...

Báo cáo khoa học: "The role of photoperiod and temperature in the induction and the release of dormancy in Pinus sylvestris L. seedlings" potx

... definition of the mostdormant stage obtained. There are nostrict borderlines to phases before andafter deep dormancy. Early and latephases of dormancy are characterized ... illustrates that seedling age at thestart of night prolongation, 7 or 12 wk,played an important role in the possibility of the buds to attain a deeper stage of dormancy. ... regimes was used as a dormancy inducing treatment. Seedlings weregrown in pots with mineral wool as a substrateand watered daily with a low concentrationnutrient solution:...

báo cáo sinh học:" The role of nurses and midwives in polio eradication and measles control activities: a survey in Sudan and Zambia" pdf

... Khartoum, Sudan and 5World Health Organization Country Office, Lusaka, ZambiaEmail: Annette Mwansa Nkowane* - nkowanemwansa@who.int; Liliane Boualam - boualaml@who.int; Salah Haithami - haithamis@sud.emro.who.int; ... during SIAs (man-agement, planning, advocacy, social mobilization, train-ing, implementation, supervision, monitoring andevaluation) and the same proportion was involved in AFPsurveillance. ... proposal, discussions, dataanalysis and review of the article. SH, ETAES and HM wereinvolved in data collection, discussion and review of arti-cle. All authors have read and approved the final...

báo cáo hóa học: "Quantitative gait analysis under dual-task in older people with mild cognitive impairment: a reliability study" doc

... interests.Gait variability under single and dual tasks for the six gait variables assessed at baselineFigure 1Gait variability under single and dual tasks for the six gait variables assessed at baseline.Journal ... Since a semi-nal study demonstrated that the inability to maintain a conversation while walking is a marker for future falls in older adults[8], walking while performing a secondarytask (dual-task ... Michael.Borrie@sjhc.london.on.ca* Corresponding author AbstractBackground: Reliability of quantitative gait assessment while dual-tasking (walking while doing a secondary task such as talking) in people with cognitive...

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