Báo cáo khoa học: " Assessment of Epidermal Growth Factor Receptor (EGFR) expression in human meningioma" docx

... of the sample exhibiting staining); 2 (21-40% of the sample exhibiting staining); 3 (41-60% of the sample exhibiting staining); 4 (61-80% of the sample exhibiting staining), and 5 (81- 100% of ... sample exhibiting staining); 3 (41-60% of the sample exhibiting staining); 4 (61-80% of the sample exhibiting staining), and 5 (81-100% of the specimen stained). The findings of t...

Ngày tải lên: 09/08/2014, 09:20

... for indicating the intrinsic kinase activity of EGFR, regardless of tissue type. Results Ligand-induced transcriptional signatures of EGFR-WT and L858R in the absence or presence of EGFR kinase ... FEBS Introduction Epidermal growth factor receptor (EGFR) is a mem- brane tyrosine kinase that is involved in the regulation of a wide variety of biological processes [1...

Ngày tải lên: 30/03/2014, 01:20

... folding in vivo The folding in vivo of an extracellular protein containin g disulfide-rich domains, the low-density lipoprotein recep- tor, has s hed new light on the folding process in the livin ... final native fold. In principle, two different factors can determine the pairing of cysteines to give disulfide bonds in multidomain proteins: the topology of the disulfides within ea...

Ngày tải lên: 23/03/2014, 13:20

... disintegrin and metalloprotein- ase) facilitated signaling by inducing the accumulation of TbRII in early endosomal vesicles and counteract- ing the internalization of TbRII into a caveolin1-posi- tive ... nucelo- porins. A lysine-rich nuclear localization signal (NLS) located in the N-terminal Mad homology 1 domain of all Smads binds to importin-b in the case of Smad3 and impor...

Ngày tải lên: 07/03/2014, 01:20

... matrix proteins such as fibronectin, laminin, and type IV col- lagen, which facilitate the cellular invasiveness at the invasion front [37]. Insulin-like growth factor- binding proteins are also ... 2008 FEBS 1007 factor- binding proteins would increase the pericellular concentration of insulin-like growth factor, and this could eventually stimulate invasive growth of tumor cells...

Ngày tải lên: 23/03/2014, 07:20

... by L -leucine in the presence, but not in the absence of Na + . The small inhibition of L -arginine in ux by L -leucine in the absence of Na + could be due probably to the presence of the system ... consisted of a rapid filtration of platelets. The present report demonstrates that two Na + -inde- pendent main systems are involved in L -arginine transport in human plate...

Ngày tải lên: 08/03/2014, 02:20

... cells/well in 100 µ l of actinomycin D containing the medium in 96-well plates. After 3 hours, the cells were incubated in the presence of GTE for 24 hrs. 10 µ l of a MTT (5 mg/ml in PBS) were ... tea polyphenols include their antioxidant activity [17], modulation of carcinogen- metabolizing enzymes [9], trapping of ultimate carcinogens [16,18], inhibitory effect in respec...

Ngày tải lên: 07/08/2014, 18:20

... androstadienol production from preg increases with increasing amounts of cyt b 5 in presence of endogenous levels of P450red. In presence of these low levels of P450red, cyt b 5 shows a slight ... of P450c17 in the formation of this metabolite. Formation of androstadienol by human and porcine P450c17, with and without cyt b 5 Using porcine and human P450c17 expressed...

Ngày tải lên: 08/03/2014, 08:20

... telomere binding protein, is present in more than 100 copies per chromosome and is associated with the entire length of the telomere. Inhibition of TRF2 binding or blocking of the binding sites has ... monitor prolifer- ation in a minor subset of cells and follow the acquisition of different markers in internal proteins linked to cell divisions. In the future, combination o...

Ngày tải lên: 17/03/2014, 09:20

... cDepartment of Veterinary Diagnostic and Production Animal Medicine, College of Veterinary Medicine, University of Iowa, Ames, Iowa USA, dDepartment of Avian Medicine, College of Veterinary Medicine, ... available for swine displaying clinical signs of infection with PRV. Currently, healthy animals are routinely immunized with inactivated (killed) or modified live virus (including...

Ngày tải lên: 07/08/2014, 15:20