Báo cáo y học: "Effects of hyaluronan treatment on lipopolysaccharide-challenged fibroblast-like synovial cell" pdf
Báo cáo y học: "Effects of hyaluronan treatment on lipopolysaccharide-challenged fibroblast-like synovial cell" pdf
... http://arthritis-research.com/content/9/1/R1Page 1 of 11(page number not for citation purposes)Vol 9 No 1Research articleEffects of hyaluronan treatment on lipopolysaccharide-challenged fibroblast-like synovial ... component of connective tissue,is a long, unbranched nonsulfated glycosaminoglycan essen-tial for the normal function of diarthrodial joints. The high con-centration (2.5–4 mg/ml) of HA in synovial ... Inhibition of leukocyte locomotionby hyaluronic acid. J Cell Sci 1981, 48:315-331.17. Presti D, Scott JE: Hyaluronan- mediated protective effectagainst cell damage caused by enzymatically producedhydroxyl...
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Báo cáo y học: "Inhibition of protein geranylgeranylation induces apoptosis in synovial fibroblasts" pdf
... inhibition of RhoA.Cardiovasc Res 2004, 61:745-755.42. Bi X, Baudry M, Liu J, Yao Y, Fu L, Brucher F, Lynch G: Inhibition of geranylgeranylation mediates the effects of 3-hydroxy-3-methylglutaryl ... and RA synovial fibroblasts equally, RA synovial fibroblasts show a furtherdecrease in viability in the presence of statins.Geranylgeranylpyrophosphate restores the viability of RA synovial ... collagen-induced arthritis; DMSO = dimethylsulfoxide; FLS = fibroblast-like synoviocytes; FPP = farnesylpyrophosphate; GGPP = geranylger-anylpyrophosphate; HMG = hydroxymethylglutaryl; IL = interleukin; OA...
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Báo cáo y học: "Effects of p-Synephrine alone and in Combination with Selected Bioflavonoids on Resting Metabolism, Blood Pressure, Heart Rate and Self-Reported Mood Changes"
... participants were randomly assigned to one of the five dou-ble-blinded treatment conditions in which they con-sumed one ounce of V-8 juice containing the following ingredient variations: Group 1: Placebo ... ratings of symp-toms increases confidence in the safety of the combi-nation as well as in the blinding procedure used in this study. Strengths of the study are the use of randomized placebo-controlled ... M. A review of the safety and efficacy of Citrus aurantium in weight management. In: Bagchi D and Preuss H, eds. Obesity: Epidemiology, Pathophysiology and Prevention. Boca Raton, FL: CRC...
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Báo cáo y học: "Effects of Flurbiprofen on CRP, TNF-α, IL-6, and Postoperative Pain of Thoracotomy"
... 1. Department of Thoracic Surgery, Konya Education and Research Hospital, Konya, Turkey; 2. Microbiology Laboratory, Konya Education and Research Hospital, Konya, Turkey Corresponding author: ... MD., Konya Education and Research Hospital, Microbiology Laboratory, Meram Yeni Yol, 42090/ Konya /Turkey. E-mail: recepkesli@yahoo.com; Phone: +90 332 324 21 60; Fax: +90 332 324 21 60. © Ivyspring ... inflammatory state characterized by the release of both proinflammatory and antiinflammatory proteins. Proinflammatory cy-tokines induce not only a local inflammation at the site of injury, but...
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Báo cáo y học: "Effects of Losartan on expression of connexins at the early stage of atherosclerosis in rabbits"
... remodeling of gap junction between ventricular myocytes under pa-thological conditions. Key words: vascular proliferation; gap junction; connexin; balloon angioplasty; statin Introduction Atherosclerosis ... markedly elevated at the early stage of coronary atherosclerosis (3). Recently, evidence showed the expression of Cx40 could also be pro-foundly increased in the early phase of artery damage. ... II on expression of gap junction channel protein connexin43 in neonatal rat ventricular myo-cytes. J Mol Cell Cardiol. 1998; 32: 800-7. 15. Polontchouk L, Ebelt B, Jackels M, Dhein S. Chronic...
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Báo cáo Y học: Inhibition of hyaluronan synthesis in Streptococcus equi FM100 by 4-methylumbelliferone doc
... regulation of tumour-associated hyaluronan. CIBA Found. Symp 13, 150–159.5. Kosaki, R., Watanabe, K. & Yamaguchi, Y. (1999) Over-production of hyaluronan by expression of the hyaluronan synthase ... level of the hasoperon containing the hyaluronan synthase gene or theprotein level of hyaluronan synthase. Solubilization of theenzyme from membranes of MU-treated cells and addition of the ... especially the distribution of different cardiolipin species, surrounding hyaluronan synthase.Keywords: hyaluronan; synthesis; Streptococcus; 4-methyl-umbelliferone; phospholipids. Hyaluronan (HA)...
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Báo cáo Y học: Effects of ATP depletion and phosphate analogues on P-glycoprotein conformation in live cells docx
... conjugates of MM12.10 and UIC2 wereprepared as described previously [26,27].Flow cytometric assaysNearly confluent monolayers of cells were harvested by2–3 min trypsin treatment [0.05% trypsin ... CsA-typedrugs may induce a special conformation adopted by Pgponly in the presence of these drugs. The first possibilitywould be confirmed if the same conformational state couldbe induced by nonsubstrate ... ATP hydrolysis Pgp undergoes conformationalchanges also affecting the drug binding site [17].Conformational changes of Pgp upon its catalytic cyclecan be detected by measuring the binding of...
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Báo cáo hóa học: " Effects of Gas Composition on Highly Efficient Surface Modification of Multi-Walled Carbon Nanotubes by Cation Treatment" pptx
... surface of the nanotubes.Specifically, by using this gas condition to conduct theplasma treatment, the highest concentration of 31.1% (after5 min exposure) of oxygenated functional groups on thesurface ... increase the concentration of oxygenated functional groups whilst also reducing theconcentration of amorphous carbon. On the other hand, treatment with pure O2gas (with the exception of increasing ... effect of gas com-position on structural integrity of the nanotubes isinsignificant in this case.ConclusionsIn this article, the effects of various H2/O2gas composi-tions on the functionalization...
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Báo cáo y học: "Impact of methylphenidate formulation on treatment patterns and hospitalizations: a retrospective analysis" pptx
... study was provided by McNeil Consumerand Specialty Pharmaceuticals.Authors' contributionsJK and ML conceptualized and designed the study. MLhad primary responsibility for analysis of ... shorter length of stay (0.62 fewerdays; p = 0.0104) in the one year post initiation on MPHmedication. While a comorbid diagnosis of anxiety ordepression was not found to have any impact on eitherthe ... citation purposes)Annals of General PsychiatryOpen AccessPrimary researchImpact of methylphenidate formulation on treatment patterns and hospitalizations: a retrospective analysisJason E...
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Báo cáo y học: "Effects of etizolam and ethyl loflazepate on the P300 event-related potential in healthy subjects" docx
... of 7 of anxiolytic benzodiazepines on neuropsychologicalfunctions and P300 components of aud itory ERP underacut e and subchronic administration of ethyl loflazepateand etizolam. Ethyl loflazepate ... cognitiveeffects of benzodiazepines after subchronic treatments[1]. Interestingly, subchronic treatment of ethyl loflaze-pate did not prolong the latency in spite of its longelimination rate.Finally, acute ... memory in the neuropsychologicaltests.Secondly, subchronic treatment with drugs producedprolongation in P300 latency only in th e Fz regions.Weak prolongation in P300 latency was seen in the...
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