Báo cáo y học: "Reactive oxygen species induce expression of vascular endothelial growth factor in chondrocytes and human articular cartilage explants" pps

... http://arthritis-research.com/content/8/6/R189 Page 1 of 8 (page number not for citation purposes) Vol 8 No 6 Research article Reactive oxygen species induce expression of vascular endothelial growth factor in chondrocytes and human articular ... and SIN-1 in chondrocytes. Conclusion By amplifying distinct ROS-dependent destructive pathways in cartilage...

Ngày tải lên: 09/08/2014, 08:23

... evidence of a link in MMP-1 and Bcl-3 expression, and indicate that both molecules are similarly affected by CDDO. CDDO dose–response study in human primary chondrocytes To examine the effects of increasing ... that human primary chondrocytes have low basal expression of MMP-1, MMP-13 and Bcl-3, and that they are increased in the presence of IL-1. Increasing d...

Ngày tải lên: 09/08/2014, 01:23

... concen- trations of DPI or A PO used did not themselves induce microglial cell toxicity as determined by MTT ass ay and trypan blue staining. ROS drive cytokine and chemokine expression in virus- infected ... phosphorylated in response to viral infection and this activation was also blocked by inhibitors of NADPH oxidase. Finally, inhibition of either of these ROS-induce...

Ngày tải lên: 19/06/2014, 22:20

... as indicated in (A), and then stained with annexin V and PI followed by flow cytometry analysis. Early apoptosis is defined by Annexin V + /PI - staining (Q4) and late apoptosis is defined by ... Belinsky SA, Lin Y: A critical role of luteolin- induced reactive oxygen species in blockage of tumor necrosis factor- activated nuclear factor- kappaB pathway and sensitizati...

Ngày tải lên: 10/08/2014, 10:20

... survival following in vitro exposure of meticil- lin-resistant Staphylococcus aureus biofilms to the antibiotics clindamycin, daptomycin, linezolid, tigecycline and vancomycin. Int J Antimicrob ... Kanchanapoom T, Khardori N. In vitro activity of vanco- mycin, quinupristin/dalfopristin, and linezolid against intact and disrupted biofilms of staphylococci. Ann Clin Microbiol...

Ngày tải lên: 26/10/2012, 09:53

... prolactin and growth hormone from pituitary cells in vitro [7]. Since then, various biological activities of TS such as inhibition of acetylcholine esterase activity [8] and induction of apoptosis in ... the enhancing effect of TS on LPS/IFN-induced NO production is caused by enhance- ment of iNOS protein induction. Effects of a-T and its derivatives on the enhancement...

Ngày tải lên: 22/02/2014, 04:20

... (LPXRFamide pep- tides) may be a conserved property of vertebrate brains, in particular the hypothalamus. In view of the immunohisto- chemical finding indicating that some of FMRFamide-like immunoreactive ... determined by a tandem mass spectrometric analysis (Fig. 3). Assignment of the observed typical fragment ions, i.e. N-terminal (b) and C-terminal (y) ions, indicated that th...

Ngày tải lên: 08/03/2014, 16:20

... 4). Effect of handling on BDNF immunoreactivity in the CA4 region of the hippocampusFigure 3 Effect of handling on BDNF immunoreactivity in the CA4 region of the hippocampus. Handling resulted in increased ... by radioimmunoassay (RIA). Data were statistically analyzed by analysis of variance (ANOVA). Results: Neonatal handling increased the ability of male rats for spatial...

Ngày tải lên: 08/08/2014, 21:20

... probably due to the stability of the mRNAs. Figure 6 Egr-1 DNA binding activity is increased by TNF-induced MEK1/2 sig-nalling in chondrocytesEgr-1 DNA binding activity is increased by TNF-induced ... Csf-1 protein levels are also induced by TNF in chondrocytes [36]. In rat articular chondrocytes, macrophage Csf-1-induced sig- nalling increases its own expression and the...

Ngày tải lên: 09/08/2014, 01:22

Ngày tải lên: 09/08/2014, 07:20