Báo cáo y học: "HLA-C locus alleles may modulate the clinical expression of psoriatic arthritis" potx

... properly cited. Abstract The aim of the present study was to evaluate the relative contribution of human leukocyte antigen (HLA)-C locus alleles in determining the risk and the clinical expression of ... additional arthritogenic risk. HLA-C alleles may modulate some aspects of the clinical expression of PsA, but these findings need confirmation. Introdu...

Ngày tải lên: 09/08/2014, 08:23

... increased expression of claudin-1 in the nucleus, but there are still large amounts of claudin-1 in the cytoplasm as well. B) All of the claudin-1 in the nucleus can be shuttled into the cytoplasm by ... com- pared to the empty vector control (Figure 4D). These data appear to support the hypothesis that nuclear overexpression of claudin-1 does not increase the in-...

Ngày tải lên: 03/11/2012, 11:17

... was then eluted with 400 m M KPB (pH 7.4). The dissociation of the subunits was confirmed by SDS/ PAGE analysis. Assay of enzyme activity ACL activity was assayed by the coupled malate dehydrog- enase ... by DNA sequencing. The expression and purification of the mutant enzyme was performed by the same procedure as that of the wild-type enzyme as described above. Phosphor...

Ngày tải lên: 08/03/2014, 22:20

... CO 8 hydrogen bonds des- cribed above, those hydrophobic interactions may account for the high stability of the peptide. Stability studies The preservation of the structured core shared by MccJ25 and ... antimicrobial activity of the thermolysin- linearized MccJ25 (MccJ25-L 1)21 : VGIGTPISFY 10 GGG AGHVPEY 20 F), previously generated for the structural characterization of...

Ngày tải lên: 23/03/2014, 21:20

... 1 Laboratory of Psychophysiology, 3rd Department of Psychiatry, Aristotle University of Thesssaloniki, Greece and 2 Laboratory of Clinical Neurophysiology, 1st Department of Neurology, Aristotle ... third in the mideye (Mr). The movement of the eyes produces a change of potential, which is recorded by the electrodes. After the recording of several movements of...

Ngày tải lên: 08/08/2014, 21:20

... psychotic depression. In some cases, the clinician or patient may prefer to avoid antipsychotic drugs altogether because of the risk of extrapyramidal side effects (EPS) in patients with psychotic ... atypical antipsychotic or electroconvulsive therapy (ECT) in treating psychotic depression. In some cases, the clinician or patient may prefer to avoid antipsychotic drugs altogeth...

Ngày tải lên: 08/08/2014, 23:21

... mineral density (BMD). (a) Trabecular bone mineral density (BMD) was determined with a metaphyseal scan at a point 3% of the length of the femur from the growth plate and the inner 45% of the area ... resolution of 70 µm, as described previously [15]. Trabecular BMD was determined with a metaphyseal scan at a point 3% of the length of the femur from the growth pl...

Ngày tải lên: 09/08/2014, 06:23

Ngày tải lên: 09/08/2014, 07:20

... 3 Quantitative estimation of the suppressive effect of dehydroxymethyle-poxyquinomicin on in vivo osteoclastogenesisQuantitative estimation of the suppressive effect of dehydroxymethyle- poxyquinomicin on ... Gene Ther 2006, 13:933-941. Figure 7 Effect of dehydroxymethylepoxyquinomicin on human osteoclastogenesis and production of matrix metalloprotease-9 by human osteoclastsE...

Ngày tải lên: 09/08/2014, 10:21

... tomography (CT) could not confirm any of the erosion-like changes found by US. Sim- ilarly, none of the US erosion-like changes in our study was confirmed by MRI. The changes may be explained by a ... distin- guish synovitis from tenosynovitis by US. The latter very prob- ably also contributes to the rather low US interobserver reproducibility for synovitis and tenosynovitis....

Ngày tải lên: 09/08/2014, 10:21