Báo cáo y học: "Deficiency of functional mannose-binding lectin is not associated with infections in patients with systemic lupus erythematosu" pptx
Báo cáo y học: "Changes of uterine blood flow after vaginal radical trachelectomy (VRT) in patients with early-stage uterine invasive cervical cancer"
... tomography (CT) imaging of patient 1. a: Left uterine artery. No descending branch was seen. b: New vessels probably arisen from ascending branch of left uterine artery. c: New vessels probably arisen ... © Ivyspring International Publisher. All rights reserved Research Paper Changes of uterine blood flow after vaginal radical trachelectomy (VRT) in patients with early-stage uterine invasive ... mortality rate of patients with cervical cancer has decreased in Japan over the past twenty years1. However, the number of patients with early invasive cervical cancer during reproductive age is...
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Báo cáo y học: "Validation of actigraphy to assess circadian organization and sleep quality in patients with advanced lung cancer" potx
... fully specifythe instrumentation type, sampling mode and analysistools in order to allow inclusion of this study in thegrowing database of cancer studies using actigraphy[16].This report investigates ... uncontrolled hypertension,arrhythmia, or angina; carcinomatous meningitis; oruncontrolled infection. Patients with a h istory of brainmetastases, or another uncontrolled primary cancer wereineligible. ... health of cancer patients [7].Wrist actigraphy is a noninvasive tool for assessing the24-hour sleep-activity cycle by monitoring continuousnon-dominant wrist movements [11]. Actigraphy hasbeen...
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Báo cáo y học: "Deficiency of functional mannose-binding lectin is not associated with infections in patients with systemic lupus erythematosu" pptx
... logistic regression model. This finding is in line with a previous study on major infections in SLE patients in the Hopkins Lupus Cohort [32].Renal insufficiency is a possible risk factor for infections. ... study functional MBL in SLE patients at risk for infection. Functional activity of the MBL pathway in serum not only is determined by mutations in the gene encoding MBL, but also is influenced by ... hydroxychloroquine use and the occurrence of major infections. This finding might be explained by the predominantuse of hydroxychloroquine in the treatment of patients with mild lupus disease activity and...
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Báo cáo y học: "The MHC2TA -168AG gene polymorphism is not associated with rheumatoid arthritis in Austrian patients" pps
... Winfried Graninger1 and Hans-Peter Brezinschek11Department of Internal Medicine, Division of Rheumatology, Medical University Graz, Austria2Clinical Institute of Medical and Laboratory ... University Graz, Austria3Department of Internal Medicine, Division of Oncology, Medical University Graz, Austria4Department of Internal Medicine, Diabetes and Metabolism Clinic, Medical University ... susceptibility toRA and the -168A>G single nucleotide polymorphism wasexamined by chi-square test. Comparison was made assuminga dominant effect (AG + GG genotypes versus AA genotype). In contrast...
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Báo cáo y học: "Association of functional variants of PTPN22 and tp53 in psoriatic arthritis: a case-control study" docx
... [14]examined p53 protein expression in synovial tissue of patients with RA and PsA. They reported differential p53 expression in the synovium of patients with RA as compared with PsA syn-ovium. ... participated in studydesign, and drafted the initial manuscript. LP assisted in gen-otyping some of the control individuals. SH aided in recruit-ment and clinical phenotyping of PsA patients. ... near 0.75 for a genotype relative risk of 1.5, and0.95 for genotype relative risks of 1.75.DiscussionThis is the first study to assess the association of the high pri-ority candidate genes...
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Báo cáo y học: " Identification of functional modules that correlate with phenotypic difference: the influence of network topology" potx
... degradationFunction:3-hydroxyacyl-CoA dehydrogenase activity (EXP, TAS)GOT1 1.30 3.69 (0.0002) Glutamate metabolismAlanine and aspartate metabolismCysteine metabolismArginine and proline metabolismTyrosine ... erythematosusFunction:Serine-type endopeptidase activity (TAS)PPID 1.32 4.04 (5e-5) Calcium signaling pathwayParkinson’s diseaseHuntington’s diseaseFunction:Cyclosporin A binding (TAS)Protein binding (IPI)HADH ... only when a passevent happens. This is to m aintain the distribution of allgenes from being artificially altered after a pplying TIF,which is very likely to occur when it is applied only togenes...
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Báo cáo y học: "Characterization of Human Erythrocytes as Potential Carrier for Pravastatin: An In Vitro Study"
... into the erythrocytes should have a degree of water solubility and resistance to degradation within erythrocytes [18]. Certain drugs have been entrapped in erythro-cytes by endocytosis, including ... pharmacologically active form of pravas-tatin is open hydroxyl-acid so that its hydrophilicity is markedly higher than that of other statins. The oral bioavailability of this statin is low due ... metabolism [5], administration of statins with certain juices [6] or in- hibition of Pgp [3]. Unfortunately these strategies are frequently associated with increase the risk of side effects of...
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Báo cáo y học: "Prevalence of Overactive Bladder, its Under-Diagnosis, and Risk Factors in a Male Urologic Veterans Population"
... urinary symptoms was given to male pa-tients who visited the general urology outpatient clinic at a Veterans Administration hospital in Brooklyn, NY. It included questions on lower urinary ... to be much higher in the urologic setting since urinary complaint is a common reason for urologic visit. Our study found that 75% of those surveyed, experienced OAB. This is almost five fold ... population. Since OAB is a compilation of lower urinary tract symptoms, the prevalence of LUTS should be higher. Irwin et al.2 in their 5-country population study reported the prevalence of any LUTS...
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Tài liệu Báo cáo Y học: Phosphorylation of initiation factor-2a is required for activation of internal translation initiation during cell differentiation ppt
... Control of eIF4E activity is mediatedby in uencing its phosphorylation status and/or its interac-tion with the eIF4E binding proteins, as well as by affectingthe integrity of eIF4G which serves ... not naturally expressed in differentiated K562 cells. In contrast with the enhancement of IRES-mediated protein synthesisduring differentiation, global protein synthesis is reduced, asjudged by polysomal ... Le, S .Y. & Elroy-Stein, O. (1999) Differ-entiation-induced internal translation of c-sis mRNA: analysis of the cis elements and their differentiation-linked binding to thehnRNP C protein. Mol....
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Báo cáo Y học: Interaction of bovine coagulation factor X and its glutamic-acid-containing fragments with phospholipid membranes A surface plasmon resonance study pdf
... assumption.DISCUSSIONCalcium binding to the Gla domain is known to be crucialfor the induction of a conformation in the domain thatmediates membrane binding. Early studies employingequilibrium dialysis established ... that mutation of Ca2+ligatingamino acids in the N-terminal part of the first EGF-likedomain of factor X in uences the amidolytic activity of theintact protein [36]. However, direct interactions ... membrane binding is cooper-ative with respect to Ca2+, presumably reflecting thecooperative Ca2+-binding to sites in the Gla domain.Interestingly, the Ca2+concentration necessary to inducemembrane-binding...
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