Báo cáo y học: "The shunt from the cyclooxygenase to lipoxygenase pathway in human osteoarthritic subchondral osteoblasts is linked with a variable expression of the 5-lipoxygenase-activating protein" doc
Báo cáo y học: "The shunt from the cyclooxygenase to lipoxygenase pathway in human osteoarthritic subchondral osteoblasts is linked with a variable expression of the 5-lipoxygenase-activating protein" doc
... osteoblasts the synthesis of LTs is linked to the tight regulation of FLAP expression, not that of 5- LO. Moreover, the basal synthesis of LTs is linked to a variable expression of FLAP in OA osteoblasts ... mechanisms of regulation of FLAP expression in OA osteoblasts. This is of special interest because the exact mechanism underlying...
Ngày tải lên: 09/08/2014, 08:23
Báo cáo y học: " Pre-treatment mortality and loss-to-follow-up in HIV-1, HIV-2 and HIV-1/HIV-2 dually infected patients eligible for antiretroviral therapy in The Gambia, West Africa" doc
... proportional hazard models of baseline characteristics and risk of pre- treatment mortality in ART-eligible patients ¶ Univariate analysis Multivariable analysis Ф Hazard ratio for death (95% CI) P Hazard ... prioritization ended within the first year of ART availability as MRC The Gambia had the capacity to counsel and initiate other eligible patients from the cohort. As...
Ngày tải lên: 10/08/2014, 05:22
Báo cáo y học: "Functional genomics analysis of low concentration of ethanol in human hepatocellular carcinoma (HepG2) cells. Role of genes involved in transcriptional and translational processes"
... Fluidics Station (Affymetrix) according to manufacturer’s instructions. Finally, the DNA microarrays were scanned with a GeneChip Scanner 3000 (Affymetrix). DNA microarray analysis Data analyses ... HMGN3 has been found to be associated with resistance against anticancer drugs including vinblastine, topotecan, paclitaxel and doxorubincin in human hepatocellular carci...
Ngày tải lên: 31/10/2012, 15:28
Báo cáo y học: "α α Upregulated hypoxia inducible factor-1α and -2α pathway in rheumatoid arthritis and osteoarthritis" pps
... NM, Chen EY, Laderoute KR, Giaccia AJ: Induction of vascular endothelial growth factor by hypoxia is modulated by a phosphatidylinositol 3-kinase/Akt signaling pathway in Ha- ras-transformed ... in OA than in RA, suggesting a relative failure of the HIF-α pathway to effectively produce a viable vasculature for OA, which is consistent with the degenerative natur...
Ngày tải lên: 09/08/2014, 01:21
Báo cáo y học: "Does switching from oral extended-release methylphenidate to the methylphenidate transdermal system affect health-related quality-of-life and medication satisfaction for children with attention-deficit/hyperactivity disorder&
... and family impact, was used to assess the impact of ADHD symptoms on the lives of children and their families at baseline and study endpoint. Satisfaction with MTS use was assessed via a Medication ... subjects withdrew from the study because of reactions at the application site that ranged from definite erythema with severe itching to normal appearance at the pa...
Ngày tải lên: 25/10/2012, 10:06
Báo cáo Y học: Identification of the 19S regulatory particle subunits from the rice 26S proteasome potx
... 33–40. 20. Yanagawa ,Y. ,Ueda,T.,Yamamoto,K.,Sasaki,T.,Tanaka,K., Hashimoto, J., Sato, T. & Nakagawa, H. (1998) Cloning and sequencing of cDNA from Oryza sativa encoding a homolog to non-ATPase subunit, ... 9S regulatory particles (RP; 700 kDa). The 20S proteasome has a cylindrical structure, consisting of a and b rings stacked in the order of abba, and each ring con...
Ngày tải lên: 08/03/2014, 16:20
Báo cáo Y học: Cytochrome c from a thermophilic bacterium has provided insights into the mechanisms of protein maturation, folding, and stability potx
... clues to the mechanism underlying protein stability at the amino-acid level. The molecular mechanisms underlying protein maturation, folding, and stability in bacterial cytochromes c are beginning ... have gained insight into the molecular mechanisms underlying cytochrome c maturation and folding as well as stability. Bacterial cytochrome c has contributed greatly to our underst...
Ngày tải lên: 24/03/2014, 03:21
Báo cáo Y học: Structural determination of the O-chain polysaccharide from Agrobacterium tumefaciens, strain DSM 30205 pot
... p.p.m. Actually, this signal, although partially overlapped with proton A- 4, appeared as a quartet because of the coupling only with methyl protons B-6 suggesting a low value of coupling constant with ... and never with L , as in the present case [14]. The only common characteristic with other plant pathogenic bacterial lipo- polysaccharide is linked to the...
Ngày tải lên: 24/03/2014, 04:21
Báo cáo Y học: Structural analysis of the lipopolysaccharide from nontypeable Haemophilus influenzae strain 1003 potx
... spectra. In addition, glycine is t entatively assign ed to O-4 of HepIII based on methylation analysis data. This investigation provides the first example of a NTHi strain with PChoattachedtoO-6ofaterminalb- D -Glcp residue ... linked to each other. Recently, t he phase -variable gene, lic 3A, was shown to encode an a- 2,3-sialyltransferase that adds Neu5Ac to termina...
Ngày tải lên: 31/03/2014, 21:21
Báo cáo y học: "4th meeting of the EU research network EUROME: From the identification of genes and cellular networks in murine models of arthritis to novel therapeutic intervention strategies in rheumatoid arthritis, London, UK, 9 March 2004" pot
... rheumatoid arthritis Analysis of gene expression using gene or protein chips and SNP analysis is a novel means to understanding the role of different proteins and pathways in different stages of arthritis. ... genetic polymorphism controlling arthritis severity. The Lund group uses pristane-induced arthritis in the rat as a model of RA. A joint-specific disease...
Ngày tải lên: 09/08/2014, 01:23