Báo cáo y học: "The shunt from the cyclooxygenase to lipoxygenase pathway in human osteoarthritic subchondral osteoblasts is linked with a variable expression of the 5-lipoxygenase-activating protein" doc
Báo cáo y học: "The shunt from the cyclooxygenase to lipoxygenase pathway in human osteoarthritic subchondral osteoblasts is linked with a variable expression of the 5-lipoxygenase-activating protein" doc
... osteoblasts the synthesis of LTs is linked to the tight regulation of FLAP expression, not that of 5-LO. Moreover, the basal synthesis of LTs is linked to a variable expression of FLAP in OA osteoblasts ... mechanisms of regulation of FLAP expression in OA osteoblasts. This is of special interest because the exactmechanism underlying a shunt from the COX to the 5-LO pathway in osteoblasts remains ... http://arthritis-research.com/content/8/6/R181Page 1 of 10(page number not for citation purposes)Vol 8 No 6Research article The shunt from the cyclooxygenase to lipoxygenase pathway in human osteoarthritic subchondral osteoblasts is linked...
- 10
- 459
- 0
Báo cáo y học: " Pre-treatment mortality and loss-to-follow-up in HIV-1, HIV-2 and HIV-1/HIV-2 dually infected patients eligible for antiretroviral therapy in The Gambia, West Africa" doc
... proportional hazard models of baseline characteristics and risk of pre-treatment mortality in ART-eligible patients¶Univariate analysis Multivariable analysisФHazard ratio for death (95% CI) P Hazard ... prioritization ended within the first year of ART availability as MRC The Gambiahad the capacity to counsel and initiate other eligiblepatients from the cohort. As a result, assessment forART became ... routinelycollected in most ART programmes in Africa as pro-gramme evaluation is most often based on number of patients who start and remain on treatment. The aim of this analysis is to investigate...
- 8
- 400
- 0
Báo cáo y học: "Functional genomics analysis of low concentration of ethanol in human hepatocellular carcinoma (HepG2) cells. Role of genes involved in transcriptional and translational processes"
... Fluidics Station (Affymetrix) according to manufacturer’s instructions. Finally, the DNA microarrays were scanned with a GeneChip Scanner 3000 (Affymetrix). DNA microarray analysis Data analyses ... HMGN3 has been found to be associated with resistance against anticancer drugs including vinblastine, topotecan, paclitaxel and doxorubincin in human hepatocellular carcinoma derived cell lines ... therapeutic approach when considering the reported high expression of the ankyrin-repeat oncoprotein (gankyrin) in human hepatocellular carcinoma . Gankyrin binds to the cell-cycle regulator...
- 8
- 702
- 0
Báo cáo y học: "α α Upregulated hypoxia inducible factor-1α and -2α pathway in rheumatoid arthritis and osteoarthritis" pps
... NM, Chen EY, Laderoute KR, Giaccia AJ: Induction of vascular endothelial growth factor by hypoxia is modulated by a phosphatidylinositol 3-kinase/Akt signaling pathway in Ha-ras-transformed ... in OAthan in RA, suggesting a relative failure of the HIF-α pathway to effectively produce a viable vasculature for OA, which is consistent with the degenerative nature of the disease. The activation ... association of the extent of HIF-1α with MVD and the VEGF/KDR activated MVD in OA is consistent with the notion that VEGF is induced by hypoxia after activation of the HIF-α pathway. This is further reinforced...
- 9
- 391
- 0
Báo cáo y học: "Does switching from oral extended-release methylphenidate to the methylphenidate transdermal system affect health-related quality-of-life and medication satisfaction for children with attention-deficit/hyperactivity disorder&
... and family impact, was used to assess the impact of ADHD symptoms on the lives of children andtheir families at baseline and study endpoint. Satisfaction with MTS use was assessed via a Medication ... subjects withdrew from the studybecause of reactions at the application site that ranged from definite erythema with severe itching to normalappearance at the patch application site with moderateitching. ... [Novartis AG, Basel, Switzerland], Concerta®[Alza Corporation, Palo Alto, CA], or Metadate CD® [UCBInc., Atlanta, GA] not to exceed 54 mg/day) for at least 30days prior to screening. At baseline,...
- 12
- 757
- 0
Báo cáo Y học: Identification of the 19S regulatory particle subunits from the rice 26S proteasome potx
... 33–40.20. Yanagawa ,Y. ,Ueda,T.,Yamamoto,K.,Sasaki,T.,Tanaka,K.,Hashimoto, J., Sato, T. & Nakagawa, H. (1998) Cloning andsequencing of cDNA from Oryza sativa encoding a homolog to non-ATPase subunit, ... 9Sregulatory particles (RP; 700 kDa). The 20S proteasomehas a cylindrical structure, consisting of a and b ringsstacked in the order of abba, and each ring contains sevenstructurally related a and ... different from that of the other organism. Protein N-myristoylationpromotes reversible and weak protein–membrane andprotein–protein interactions. Usually, myristate acts with other mechanisms to r...
- 10
- 495
- 0
Báo cáo Y học: Cytochrome c from a thermophilic bacterium has provided insights into the mechanisms of protein maturation, folding, and stability potx
... clues to the mechanism underlying proteinstability at the amino-acid level. The molecular mechanismsunderlying protein maturation, folding, and stability in bacterial cytochromes c are beginning ... have gained insight into the molecularmechanisms underlying cytochrome c maturation andfolding as well as stability. Bacterial cytochrome c hascontributed greatly to our understanding in these ... AS A MODEL FORPROTEIN STABILITY STUDIESProteins isolated from thermophilic bacteria are usuallystable to heat and chemical denaturants, indicating that theymust have most of the determinants...
- 7
- 369
- 0
Báo cáo Y học: Structural determination of the O-chain polysaccharide from Agrobacterium tumefaciens, strain DSM 30205 pot
... p.p.m.Actually, this signal, although partially overlapped with proton A- 4, appeared as a quartet because of the couplingonly with methyl protons B-6 suggesting a low value of coupling constant with ... andnever with L, as in the present case [14]. The only commoncharacteristic with other plant pathogenic bacterial lipo-polysaccharide is linked to the partial hydrophobic nature of the O-chain moiety ... compositionalanalysis and revealed the presence of 3-hydroxymyristic acidtogether with minor amounts of palmitic, 3-hydroxy-palmitic, 2-hydroxy-palmitic and stearic acids.Monosaccharide composition...
- 4
- 360
- 0
Báo cáo Y học: Structural analysis of the lipopolysaccharide from nontypeable Haemophilus influenzae strain 1003 potx
... spectra. In addition,glycine is t entatively assign ed to O-4 of HepIII based onmethylation analysis data.This investigation provides the first example of a NTHistrain with PChoattachedtoO-6ofaterminalb-D-Glcpresidue ... linked to each other. Recently, t he phase -variable gene, lic 3A, wasshown to encode an a- 2,3-sialyltransferase that addsNeu5Ac to terminal lactose [30]. The core oligosaccharide of NTHi strain 1003 ... experiments(DQF-COSY and TOCSY) and the chemical s hift d ata a reshown in Tables 2 and 3. Subspectra corresponding to the individual glycosyl residues were identified on the basis of spin-connectivity pathways...
- 11
- 521
- 0
Báo cáo y học: "4th meeting of the EU research network EUROME: From the identification of genes and cellular networks in murine models of arthritis to novel therapeutic intervention strategies in rheumatoid arthritis, London, UK, 9 March 2004" pot
... rheumatoidarthritisAnalysis of gene expression using gene or protein chipsand SNP analysis is a novel means to understanding the role of different proteins and pathways in different stages of arthritis. ... geneticpolymorphism controlling arthritis severity. The Lund groupuses pristane-induced arthritis in the rat as a model of RA. A joint-specific disease with many similarities to human RAdevelops after a single ... synovial vessel density is a feature of RA andseveral angiogenic factors are expressed in RA, includingvascular endothelial growth factor (VEGF). The Londongroup has investigated the effect of angiogenesis...
- 4
- 288
- 0
Từ khóa: báo cáo khoa học y họcbáo cáo y họcbáo cáo tóm tắt thành tích tập thểbáo cáo y học cổ truyềnphân tích báo cáo lưu chuyển tiền tệ như thế nàochuyên đề điện xoay chiều theo dạngNghiên cứu sự hình thành lớp bảo vệ và khả năng chống ăn mòn của thép bền thời tiết trong điều kiện khí hậu nhiệt đới việt namNghiên cứu tổ chức pha chế, đánh giá chất lượng thuốc tiêm truyền trong điều kiện dã ngoạiđề thi thử THPTQG 2019 toán THPT chuyên thái bình lần 2 có lời giảiBiện pháp quản lý hoạt động dạy hát xoan trong trường trung học cơ sở huyện lâm thao, phú thọGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitNGHIÊN CỨU CÔNG NGHỆ KẾT NỐI VÔ TUYẾN CỰ LY XA, CÔNG SUẤT THẤP LPWAN SLIDENghiên cứu về mô hình thống kê học sâu và ứng dụng trong nhận dạng chữ viết tay hạn chếĐịnh tội danh từ thực tiễn huyện Cần Giuộc, tỉnh Long An (Luận văn thạc sĩ)Tìm hiểu công cụ đánh giá hệ thống đảm bảo an toàn hệ thống thông tinThơ nôm tứ tuyệt trào phúng hồ xuân hươngThiết kế và chế tạo mô hình biến tần (inverter) cho máy điều hòa không khíSở hữu ruộng đất và kinh tế nông nghiệp châu ôn (lạng sơn) nửa đầu thế kỷ XIXTăng trưởng tín dụng hộ sản xuất nông nghiệp tại Ngân hàng Nông nghiệp và Phát triển nông thôn Việt Nam chi nhánh tỉnh Bắc Giang (Luận văn thạc sĩ)Giáo án Sinh học 11 bài 15: Tiêu hóa ở động vậtGiáo án Sinh học 11 bài 15: Tiêu hóa ở động vậtGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtTrách nhiệm của người sử dụng lao động đối với lao động nữ theo pháp luật lao động Việt Nam từ thực tiễn các khu công nghiệp tại thành phố Hồ Chí Minh (Luận văn thạc sĩ)