Báo cáo y học: "Novel self-epitopes derived from aggrecan, fibrillin, and matri" ppt

... following cytokines were measured: IL-1α, IL-1β, IL-5, IL-10, IL-12, IL-18, tumor necrosis factor-α (TNF-α), and IFN-γ. Cytokine analysis by lymphocyte intracellular staining and flow cytometry T-cell ... Carducci 15, 92100 Milan, Italy 6 Department of Biochemistry and Cell Biology, Faculty of Veterinary Medicine, Utrecht University, Yalelaan 1, 3584 CL Utrecht, The Netherlands Correspo...

Ngày tải lên: 09/08/2014, 08:23

... the N-ethylsuccinimidocysteines by hydrolysis [7]. Selected peptides were sequenced to reveal the positions of the alkylated cysteines. The phe- nylthiohydantoin (PTH) derivative of N-ethylsuccini- midocysteine ... N-ethylsuccini- midocysteine elutes between PTH-Pro and PTH-Met in the HPLC system of the sequencer employed. The presence of alkylated cysteines at positions 4 and 17 in some...

Ngày tải lên: 16/03/2014, 11:20

... inter- mediate form 5-hydroxyisourate, and subsequent hydrolysis of this produces 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazo- line, which is decarboxylated to S-(+)-allantoin [63]. The enzymes carrying out ... to marked dampening by the normal abundance of catalase on erythrocytes [51,59,60] and potentially by other plasma antioxidant defenses. Yet methemoglobinemia and/ or hemolysis have...

Ngày tải lên: 09/08/2014, 14:21

... 396–402. 113. Drum,C.L.,Shen ,Y. ,Rice,P.A.,Bohm,A.&Tang,W.J.(2001) Crystallization and preliminary X-ray study of the edema factor exotoxin adenylyl cyclase domain from Bacillus anthracis in ... catalytic activity of the enzyme approximately 1000-fold. Surpris- ingly, the activation of the enzyme is not achieved by dramatically changing the architecture of the active site, nor by rem...

Ngày tải lên: 17/03/2014, 09:20

... together with binding to their cognate ligands. Importantly, ASV derived from VEGF receptor type 1 and Tie1, and to a lesser extent from VEGF receptor type 2 and fibroblast growth factor receptor ... by decreased joint inflammation and destruction. Conclusion The present study shows that unique ASV derived from receptors that play key roles in angiogenesis – namely, VEGF rec...

Ngày tải lên: 09/08/2014, 10:23

... the manuscript.XZ: Performed confocal microscopy and par- ticipated in study and conjugate design and drafting the manuscript.SG: Performed synthetic and quality control chemistry and participated in drafting ... manuscript.SP: Performed synthetic and quality control chemistry.OD: Performed HIV and general toxicity studies.MJL: Partici- pated in study and conjugate design and...

Ngày tải lên: 10/08/2014, 05:20

... data on phyllokinin (braykinyl-isoleucyl-tyrosine-0-sulphate) and bradykinyl-isoleucyl-tyrosine. Br.J.Pharmacol.27, 479–485. 16. Yasuhara, T., Hira, M., Nakajima, T., Yanaihara, N. & Yanaihara, ... This sensitivity is well within the capability of the ES-MS system employed. The primary structural diversity displayed within amphibian skin bradykinins may not simply be due to phylogenetic...

Ngày tải lên: 21/02/2014, 15:20

... Lai 3 and Haining Yu 1,2 1 College of Life Sciences, Hebei Normal University, Shijiazhuang, China 2 School of Life Science and Biotechnology, Dalian University of Technology, China 3 Key Laboratory ... with gold, they were analysed using a Hitachi S-4800 SEM. Haemolysis, serum stability and the effect of pH on antimicrobial activity Haemolysis assays were conducted as previously describ...

Ngày tải lên: 22/03/2014, 21:21

... http://www.medsci.org 117 American Journal of Ophthalmology: Delair E, Monnet D, Grabar S, Dupouy-Camet J, Yera H, Brézin AP. Respective roles of acquired and con- genital infections in presumed ocular ... toxoplas- mosis. Am J Ophthalmol 2008;146:851-5). • Optical Coherence Tomography in ocular toxoplasmosis • Usefulness of vitrectomy in the treatment of ocular toxoplasmosis • Upd...

Ngày tải lên: 03/11/2012, 11:11

... were purchased from Pharmacia. Bio-Gel HTP hydroxylapatite was from Bio-Rad. [a- 32 P]ATP, [ 14 C]phenylalanine and [ 3 H]GDP were purchased from Amersham. CTP, GDP, phosphoenolpyruvate and phosphoenolpyruvate ... kinase were from Sigma. tRNA nucleotidyltransferase was isolated from yeast as described [17]. Bovine catalase was from Serva, rabbit glyceraldehyde-3¢-phosphate deh...

Ngày tải lên: 21/02/2014, 15:20