Báo cáo y học: "Fibroblast activation protein is expressed by rheumatoid myofibroblast-like synoviocytes" ppt
Báo cáo y học: "Fibroblast activation protein is expressed by rheumatoid myofibroblast-like synoviocytes" ppt
... arthritisImmunohistochemical analysis of activation markers in synovial membranes of rheumatoid arthritis. Expression of fibroblast activation protein (FAP) is accompanied by accumulation of activation ... staining intensity. Discussion The main finding of our study is the demonstration that FAP is expressed by synovial fibroblasts in patients with RA and OA. It is we...
Ngày tải lên: 09/08/2014, 08:23
Báo cáo y học: "Fibroblast activation protein alpha is expressed by chondrocytes following a pro-inflammatory stimulus and is elevated in osteoarthriti" docx
... LGVYEVEDQITAVR 969.56 (2+) 534–550 YPLLIQVYGGPCSQSVR 697.41 (2+) 510–521 LKVDDITLWYK 786.47 (2+) 551–564 SIFAVSWISYLASK 715.65 (3+) 144–161 NELPRPIQYLCWSPVGSK 776.36 (3+) 124–142 YSYTATYHIYDLTNGEFIR 1098.96 ... experimental metastasis [22,23]. Immunohistochemistry has shown that FAPα is transiently expressed in certain normal fetal mesen- chymal tissues, but in normal adult tissues FAPα e...
Ngày tải lên: 09/08/2014, 07:20
Báo cáo y học: "Somatic mutations in the mitochondria of rheumatoid arthritis synoviocytes" ppt
... mitochondria of rheumatoid arthritis synoviocytes Tanya R Da Sylva 1 , Alison Connor 2 , Yvonne Mburu 1 , Edward Keystone 3 and Gillian E Wu 1 1 Department of Biology, York University, Toronto, ... synoviocytes from patients with osteoarthritis (OA). This disease was chosen because it is pri- marily a noninflammatory syndrome that is not thought to be directly dependent on the immune...
Ngày tải lên: 09/08/2014, 06:23
Báo cáo y học: "Voluntary activation failure is detectable in some myositis patients with persisting quadriceps femoris weakness: an observational study" ppt
... Idiopathic Inflammatory Myopathies: Polymyositis, Dermatomyositis, and related disorders. Ann Intern Med 1989, 111:143-157. 7. Olsen N, Park J: Inflammatory myopathies: issues in diagnosis and management. Arthritis ... C-reactive protein; CyA, cyclosporin A; DM, dermatomyositis; EMG, electromyography; IIM, idiopathic inflammatory myositis; IU/l, international units per litre; MCTD, mixed co...
Ngày tải lên: 09/08/2014, 07:20
Báo cáo y học: "MMP-3 expression and release by rheumatoid arthritis fibroblast-like synoviocytes induced with a bacterial ligand of integrin α5β" pdf
... performed. MBZ is supported by a grant from the French Ministry of Research and Technologies, and VAD, by grants from Région Alsace, Amgen, and Wyeth Lederle. This work was supported in part by a grant ... syno- vial tissue of patients with advanced rheumatoid arthritis or osteoarthritis: analysis with gas chromatography-mass spec- trometry and pan-bacterial polymerase chain react...
Ngày tải lên: 09/08/2014, 06:22
Báo cáo y học: "Adalimumab clinical efficacy is associated with rheumatoid factor and anti-cyclic citrullinated peptide antibody titer reduction: a one-year prospective study" potx
... treatment with adalimu- mab by using enzyme-immunoassay (EIA) (Pharmacia Diag- nostics, Friburg, Germany); positive samples were also evaluated by Farr assay and by indirect immunofluorescence with ... antibody assay in early rheumatoid arthritis for predicting five year radiographic damage. Ann Rheum Dis 2003, 62:120-126. 35. Bas S, Genevay S, Metyer O, Gabay C: Anti-cyclic citrullin...
Ngày tải lên: 09/08/2014, 07:20
Báo cáo y học: "An important step towards completing the rheumatoid arthritis cycle" pptx
... that citrullination is intimately involved in the pathophysiology of rheumatoid arthritis and complete our model (the rheumatoid arthritis cycle) for the development and chronic nature of this disease. Rheumatoid ... of the RA cycle, as depicted in Figure 1 and discussed by us and others previously [4-6]. In this model for the development and chronicity of RA at least five steps can...
Ngày tải lên: 09/08/2014, 13:21
Báo cáo y học: "Interferon-induced protein IFIT4 is associated with systemic lupus erythematosus and promotes differentiation of monocytes into dendritic cell-like cells" pdf
... DCLCs were analyzed by flow cytometry. Appropriate fluorochrome or isotype control mAbs of each antibody species were used as negative controls. Shaded histograms represent isotype control antibodies. ... for 6 days. Phorbol-12-myristate-13- acetate (PMA) (10 ng/ml) was added for another day. Finally, the cul- ture medium was measured to assess IFN-γ and IL-4 produced by T cells by EL...
Ngày tải lên: 09/08/2014, 10:23
Báo cáo y học: "Dynamic activation of bone morphogenetic protein signaling in collagen-induced arthritis supports their role in joint homeostasis and disease" ppsx
... Luyten FP: Bone morphoge- netic proteins 2 and 6, expressed in arthritic synovium, are regulated by proinflammatory cytokines and differentially modulate fibroblast-like synoviocyte apoptosis. ... B, Luyten FP, Verdonk PC, Tak PP, Boots AH, Baeten D: Melanoma Inhibitory Activity, a biomarker related to chondrocyte anabolism, is reversibly suppressed by proinflammatory cytokines in rh...
Ngày tải lên: 09/08/2014, 13:22
Báo cáo y học: "Heat shock protein 60 reactive T cells in juvenile idiopathic arthritis: what is ne" pdf
... can be distinguished by their mecha- nism of suppression and phenotype. In general, suppression by Tregs is mediated by cell-cell contact and production of suppressive cytokines. Naturally occurring ... marked by red arrows) is highly expressed in synovial lining membranes in the inflamed joints of JIA patients. (b) HSP60 is released by the synovial tissues in the inflamed j...
Ngày tải lên: 09/08/2014, 14:20