Báo cáo y học: "Novel IL10 gene family associations with systemic juvenile idiopathic arthritis" ppt
Báo cáo y học: "Novel IL10 gene family associations with systemic juvenile idiopathic arthritis" ppt
... articleNovel IL10 gene family associations with systemic juvenile idiopathic arthritisMark S Fife1, Ana Gutierrez1, Emma M Ogilvie1, Carmel JW Stock1, Jane M Samuel1, Wendy Thomson2, ... broaden the analysis to the IL10 gene family in sJIA usinghaplotype analysis.In this study we have shown a significant increased prevalenceof the IL10- 1082 A allele, associated with low IL10 produc-tion, ... children with sJIA, indicative of acentral role for these cytokines in disease pathogenesis.Table 2Haplotype analysis results for association in systemic juvenile idiopathic arthritisHaplotype (IL10 -1082/IL20-468)...
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Báo cáo y học: " Novel venom gene discover Novel venom gene discovery in the platypusy in the platypus" pot
... best chance to identify completely novelplatypus venom genes with no homology to existingtoxins.ConclusionsWe have identified proteins encoded by genes expressedin the platypus venom gland that ... components:alpha-latrotoxin, CRiSPs, cytolytic toxinGenes encoding proteins with homology to invertebratevenom toxins were also f ound. For example, we identi-fied seven genes encoding peptides with homology tospider ... independently in different animals, further sup-porting the use of our homo logy approach to identifyplatypus venom genes. We thus identified novel putativeplatypus venom genes by using TBLASTN...
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Báo cáo y học: "Cognitive remediation therapy for patients with anorexia nervosa: preliminary findings" pptx
... Central yours — you keep the copyrightSubmit your manuscript here:http://www.biomedcentral.com/info/publishing_adv.aspBioMedcentralAnnals of General Psychiatry 2007, 6:14 http://www.annals-general-psychiatry.com/content/6/1/14Page ... treatment was positively received by patients with along history of AN and who had several attempts with psychological interventions which may have failed.Patients commented that they found the intervention ... people with anorexia: Apilot study. AED: International Conference on Eating Disorders,Barcelona, Spain (abstract); 2006. Annals of General Psychiatry 2007, 6:14 http://www.annals-general-psychiatry.com/content/6/1/14Page...
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Báo cáo y học: "α Paradoxical effects of tumour necrosis factor-α in adjuvant-induced arthritis" pptx
... frequency of relapse in patients with existing multiple sclerosis [4]. Similarly, in experimentalautoimmune encephalomyelitis (EAE), TNFα-/-mice develop-ed enhanced inflammation and demyelination, ... responses inTNFα treated rats immunised with a control antigen (hen egglysozyme) would argue against a generalised immuno-suppressive effect [1]. Another possibility is that TNFαmodulates antigen ... Nature 1988, 331:356-358.8. Kontoyiannis D, Kollias G: Accelerated autoimmunity and lupusnephritis in NZB mice with an engineered heterozygous defi-ciency in tumor necrosis factor. Eur J Immunol...
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Báo cáo y học: "Unusual presentation of hereditary neuropathy with liability to pressure palsies" pptx
... hereditary neuropathy with liability to pressurepalsies. Neurology 2001, 56:1415.13. Crum BA, Sorenson EJ, Abad GA, Dyck PJ: Fulminant case ofhereditary neuropathy with liability to pressure palsy. ... and ulnar neuropathy at the elbow with mildperipheral demyelinating polyneuropathy associated with the PMP-22 gene deletion.BackgroundHereditary neuropathy with liability to pressure palsies(HNPP) ... Horowitz SH, Spollen LE, Yu W: Hereditary neuropathy with lia-bility to pressure palsy: fulminant development with axonalloss during military training. J Neurol Neurosurg Psychiatry 2004,75:1629-31.15....
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Báo cáo Y học: Novel regulatory regions found downstream of the rat B29/Ig-b gene docx
... arepressed gene during the expression of cell type-specificgenes. Yet all regions of this locus are reportedly alwaysrelaxed in the human a-globin locus [38]. Thus, before celltype-specific gene expression ... with phenol,precipitated with ethan ol, and analyze d on a 5% polyacryl-amide sequencing gel.RESULTS Y3 cell-specific DNase I hypersensitive sitesB29/Ig-b mRNA was detected in rat plasmacytoma-derived Y3 ... DNase I hypersensitivity by SkM sodium channel and B29/Ig-b gene chromatins of Y3 cells (B).(A) Poly ( A)-rich RNA (3.0 lg) electrophoresed on a 2.2-MHCHO/1% agarose gel and hybridized with 32P-labeled...
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Báo cáo y học: "Novel approaches to gene expression analysis of active polyarticular juvenile rheumatoid arthritis." pdf
... oxidesynthase.Adenylate cyclase, 3.4 6.4 1.9 Adenylate cyclase (type 7), an ATP-pyrophosphate lyase;type VII converts ATP to cAMPC. Genes expressed in active untreated patients only Gene bank ... uniquelyexpressed genes.Selection of hypervariable (HV) genesTo have an opportunity to evaluate inhomogeneity in gene expression variability, it is necessary to normalize this vari-ability to ... http://arthritis-research.com/content/supplementary/ar1018-s1.xlsInterestingly, literature searches and pathway analysisrevealed that nearly all of the 19 genes identified by thisanalysis are either directly or indirectly associated with immune...
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Tài liệu Báo cáo Y học: Novel bradykinins and their precursor cDNAs from European yellow-bellied toad (Bombina variegata) skin potx
... This sensitivity is well within the capabilityof the ES-MS system employed.The primary structural diversity displayed withinamphibian skin bradykinins may not simply be due tophylogenetic differences ... (Tokyo) 16, 769–774.15. Anastasi, A., Bertaccini, G. & Erspamer, V. (1966) Pharmacolo-gical data on phyllokinin (braykinyl-isoleucyl-tyrosine-0-sulphate)and bradykinyl-isoleucyl-tyrosine. ... similarity with heterogeneity predomi-nantly localized to the C-terminal regions. Mature peptideswere flanked both N- and C-terminally by identicalpropeptide convertase processing sites probably involvinga...
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Tài liệu Báo cáo Y học: Novel complexes of mammalian translation elongation factor eEF1AÆGDP with uncharged tRNA and aminoacyl-tRNA synthetase potx
... tRNA with eEF1AÆGDP were shown tocoincide with those of aminoacyl-tRNA in the complex with EF1AÆGTP revealed by X-ray analysis [28].Specific association of the [eEF1AÆGDPÆtRNA] complex with ... °C. The carboxymethyl dextran matrix of the sensorchip was activated by a 30-lL injection of the mixtureof 0.2M1-ethyl-3-[(3-dimethylamino)propyl]carbodiimideand 0.05MN-hydroxysuccinimide ... associationof the enzyme with tRNA bound to eEF1AÆGDP thermo-dynamically favorable. In this quaternary complex, atransfer of tRNA from the factor to ARS may occur. Asthe quaternary complex [eEF1AÆGDPÆtRNAÆARS]...
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Báo cáo Y học: Novel fish hypothalamic neuropeptide Cloning of a cDNA encoding the precursor polypeptide and identification and localization of the mature peptide pptx
... polymerase [Ex Taq polymerase(Takara Shuzo, Kyoto, Japan) or gene Taq polymerase(NIPPON GENE, Tokyo, Japan)] and 0.2 mMdNTP on athermal cycler (Program Temp Control System PC-700,Astec, ... hypothalamic RFamide-related peptide identified byimmunoaffinity chromatography and mass spectrometry. FEBSLett. 512, 255–258.15. Fukusumi, S., Habata, Y. , Yoshida, H., Iijima, N., Kawamata, Y. , ... with sequences complementary to the precursor mRNA.Expression was detected finally by enzyme immunohisto-chemistry. An intense expression of goldfish LPXRFamidepeptide mRNA was detected only...
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