Báo cáo y học: "Serum, urinary, and salivary nitric oxide in rheumatoid arthritis: complexities of interpreting nitric oxide measures" doc

... properly cited. Abstract Nitric oxide (NO) may play important roles in rheumatoid arthritis (RA). RA is an inflammatory disease involving joints and other systems including salivary glands. To ... for individual differences in creatinine clearances. The finding of increased NOx and NOx/creatinine ratios in serum (but not in urine) in patients with RA raised the possibi...

Ngày tải lên: 09/08/2014, 08:22

... & Ringe, D. (1994) Role of the divalent metal ion in sugar binding, ring opening, and isomerization by D-xylose isomerase: replacement of a catalytic metal by an amino acid. Biochemistry 33, ... uncharged polar amino acids (i.e. Q, N, S, and T) and an increase in charged amino-acid residues (i.e. K, E, and R) in hyperthermophilic proteins. As S and T can catalyze the d...

Ngày tải lên: 22/02/2014, 07:20

... disease activity score, the use of this score represents a handicap for the evaluation of the efficacy of cyclosporin A on disease activ- ity. On the other hand, cyclosporin A inhibits the synthesis of IL-17 ... Spain. Throughout the follow-up of the EMECAR cohort, the percentage of patients without any DMARD declined while the frequency of patients on combined therapy increased...

Ngày tải lên: 09/08/2014, 13:22

... Combination Therapy Trial Group: Delay to institution of therapy and induc- tion of remission using single-drug or combination-disease- modifying antirheumatic drug therapy in early rheumatoid arthritis. ... 9-month RCT of hydrox- ychloroquine versus placebo in early RA. Three years after the study ended, early DMARD therapy still resulted in less pain and disability. The re...

Ngày tải lên: 09/08/2014, 01:23

... Sugawara K, Ikenaka T: Conver- sion of peanut trypsin-chymotrypsin inhibitor B-III to a chymo- trypsin inhibitor by deimination of the P1 arginine residues in two reactive sites. J Biochem 1987, ... representing candidate autoantigens in RA, including protein and overlapping pep- tides representing native and citrullinated fibrinogen. Synovial microarray analysis demonstrated targ...

Ngày tải lên: 09/08/2014, 10:23

... group in the case– control study is, in part, probably related to the combined use of both a highly sensitive protein stain and highly sensitive immunofixation electrophoresis. Using similar analytical ... and NIH between 1993 and 2000, and subjects from a study of the underlying mechanisms of primary fibromyalgia (fibromyal- gia syndrome (FMS)) from 1986 to 1989 and from...

Ngày tải lên: 09/08/2014, 10:21

... and clinical studies in animal models and human beings are needed to un- derstand molecular elements, ligand and receptors, involved in the mode of action of ozone and HBO. Finally, according ... mechanisms of hyperbaric oxygen in the treatment of ischemia-reperfusion injury. Int Anesthesiol Clin 2000;38:91-109 31. Korkmaz A, Oter S, Deveci S, et al. Involvement o...

Ngày tải lên: 25/10/2012, 11:18

... vimentin is present in synovial membranes and is released in increased amounts in response to growth factors and proinflammatory cytokines, suggesting involvement in the pathophysiology of RA [24]. The ... for diagnosing RA. APF detection is avail- able only at specialized laboratories, as obtaining and stand- ardizing the substrate is technically challenging, and interpret...

Ngày tải lên: 09/08/2014, 01:22

... Hickling P: Disease activ- ity in longstanding ankylosing spondylitis – a correlation of clinical and magnetic resonance imaging findings. Clin Rheu- matol 2008, 27:449-455. 25. Baraliakos X, Landewe ... recruitment and participated in data entry. JL partici- pated in data entry and analysis. FMM conceived of the study and coordinated patient recruitment, data entry, data an...

Ngày tải lên: 09/08/2014, 01:22

... in elucidating the crosstalk between the immune system and bone and in uncovering the mechanism by which sex-steroids, infection and inflammation lead to bone loss by disregulating T lymphocyte ... approximately 50% of the increase in the number of T cells in the periphery, while the remaining 50% is due to enhanced peripheral expansion. Similarly, thymectomy decreases by ap...

Ngày tải lên: 09/08/2014, 10:20