Báo cáo y học: "Coexpression and interaction of CXCL10 and CD26 in mesenchymal cells by synergising inflammatory cytokines: CXCL8 and CXCL10 are discriminative markers for autoimmune arthropathie" doc

... of 14 (page number not for citation purposes) Vol 8 No 4 Research article Coexpression and interaction of CXCL10 and CD26 in mesenchymal cells by synergising inflammatory cytokines: CXCL8 and ... the study. Results Synergistic induction of CXCL10 ligands in fibroblasts and endothelial cells by inflammatory cytokines. The lymphocyte chemotactic C...

Ngày tải lên: 09/08/2014, 08:22

... extremely rare in the absence of systemic disease. The co-existence of sys- temic and local disease is taken in to consideration i n the pathogenesis of these ruptures. The pre-disposing factors for ... vely, the patient was immobi lized first in bilateral cylinder casts for six weeks, then in knee braces for the next four weeks. His knees were actively mobi- lized durin...

Ngày tải lên: 10/08/2014, 23:22

... more challenging as shown by the lower AUCs in ROC curves in this study when compared to mortality prediction alone. While age and comorbidities are major drivers of mortality, extent and severity of infection ... improves clinical decision making and adds timely information beyond that of readily available information from clinical examination. Observational studies alone...

Ngày tải lên: 25/10/2012, 10:02

... noteworthy that these B-type cyclins are strictly regulated in terms of protein amounts during cell cycling by transcription and ubiquitin-mediated proteolysis [11]. Second, the kinase activity of ... SDS/polyacrylamide gel and stained with Coomassie Blue. In vitro kinase assay In this study, mainly two types of in vitro kinase assay were performed. First, we examined wh...

Ngày tải lên: 17/03/2014, 23:20

... significantly affect the proteoglycan con- tent in any layer of the articular cartilage. Figure 3 Safranin O staining intensity in the epiphyseal growth plate of the femo-ral condyleSafranin O staining intensity ... total score of 8 for acute inflammation. Chronic joint inflammation – based on the parameters hyper- plasia of synovial lining cells, infiltration by mononuclear...

Ngày tải lên: 09/08/2014, 06:22

... variability of learning requirements for the technique [26]. The use of MSUS by the podiatrist within this study did reveal good sensitivity and specificity for detecting fore- foot bursitis (82.4% and ... challenges in training for this skill are primarily due to the quality and interpre- tation of the ultrasound images that are acknowledged as being greatly depende...

Ngày tải lên: 10/08/2014, 21:23

... with normal intervening lung parenchyma. They are lined by a smooth, definable wall that does not enhance and are predominantly basilar and subpleural, though small intraparenchymal cysts can also be ... series [5]. Lung cysts are frequently seen in BHDS. A recent study found multiple pulmonary cysts in 89% of CT scans of BHDS patients [6]. Cysts in BHDS are typically...

Ngày tải lên: 11/08/2014, 12:20

... engagement in quality improvement as a distinct career pathway. Involving such physicians in medical emergency teams will likely facilitate the dual roles of these as a clinical outreach arm of the intensive ... intensive care unit and in identifying problems in care and leading to strategies to reduce them. Adverse events, defined as undesirable outcomes caused by medical c...

Ngày tải lên: 25/10/2012, 10:06

... were residues Gly261 and Gly262. The replacement of Gly262 by Ala resulted in an inactive enzyme. Substitution of Gly261 by Ala resulted to an enzyme with lower stability and increased energy of activation. ... more active. Determination of E a and thermodynamic parameters for wild-type and mutant enzymes In order to elucidate the effect of mutations in terms of...

Ngày tải lên: 22/02/2014, 04:20

... motifs are hydrolysed by hK2 in semenogelins I and II whereas the Arg–Met motif is cleaved in the plasminogen activator inhibitor-1 and the Arg–Gln motif is cleaved in IGF-BP-2. Using each of the ... constant and gave a percentage of hydrolysis of only 20% confirming the preference for arginine in the P1 position. No cleavage was observed with the two peptides that di...

Ngày tải lên: 31/03/2014, 23:20