... nuclear factor-kappa-B activation. In summary, RANK-L is expressed by inflammatory and normalneutrophils, unlike OPG and RANK, which are expressed onlyby neutrophils exposed to an inflammatory ... detection of the mRNA. OPG, osteoprotegerin; PCR, polymerase chain reaction; RANK, receptor activator of nuclear factor-kappa-B; RANK-L, ligand of receptor activator of nuclear factor-kappa-B; TRAF6, ... important role in the IL-4-induced protectionfrom apoptosis. Int Immunol 20 01, 13 :14 79 -14 87.39. McDonald PP, Bald A, Cassatella MA: Activation of the NF-kap-paB pathway by inflammatory stimuli in...