Báo cáo y học: "Type IX collagen deficiency enhances the binding of cartilage-specific antibodies and arthritis severity" docx

... affect chondrocytes pro- foundly, and chondrocytes might possibly try to compensate for the CIX deficiency by the overexpression of cartilage components. To test our hypothesis about whether cartilage ... instability and changed exposure of Figure 4 Improved binding of anti -collagen type II antibodies to cartilage defi-cient in collagen type IXImproved binding of a...

Ngày tải lên: 09/08/2014, 08:22

... strategy for improving the long-term health of children and ado- lescents may be in creating a lifestyle pattern of regular physical activity and healthy eating that will carry over to the adult years ... as grounded theory. Mixed methods designs will allows us to understand more fully not only if KTE strate- gies are effective, but also more importantly why or why not, how and...

Ngày tải lên: 11/08/2014, 05:21

... sensitivity of 71% and a specificity of 84% for the diagnosis of HSV [1]. The inflammation of small blood vessels, most com- monly postcapillary venules, is the cardinal histologic fea- ture of LCV ... secondary to Type III hypersensitivity can be augmented through the use of dapsone [19]. Bacteremia caused by E. coli secondary to a urinary tract infection delayed the...

Ngày tải lên: 11/08/2014, 11:20

... copies of C3d can enhance the immunogenicity of the antigen sM2, but its ability to increase the antibody titer is lower than that of the fusion proteins. The transformation ability of lymphocytes ... cleaved into C3a and C3b by the C3 convertase [4]. Further prote- olytic cleavage of C3b results in the formation of C3c and C3dg. The C3dg product can be further...

Ngày tải lên: 12/08/2014, 04:20

... Introduction Spleen tyrosine kinase (Syk) is a cytoplasmic tyrosine kinase of 72 kDa and a member of the ZAP70 (ζ-chain- associated protein kinase of 70 kDa)/Syk family of the non-receptor-type protein tyrosine ... necessary for BCR-mediated tyrosine phosphorylation and signal transduction [6,15]. 2.2. Syk and phagocytes FcγR, one of the classic immunoreceptors, typi...

Ngày tải lên: 12/08/2014, 15:22

... Anal- ysis of BAL fluid has been found useful in studying the pathophysiology of ARDS [2,14] and other pulmonary dis- eases [15,16]. In this study, we analyzed the effects of two ventilatory modes, ... purposes) endothelial cells induced by mechanical stimulation may lead to the modulation of the activation of neutrophils and macrophages in the lung via proinflammatory...

Ngày tải lên: 12/08/2014, 18:20

... likely to involve only one member of a complex and thus, because they will cause disruption to the 'balance' of any complex in which they are involved, they will have a greater tendency ... arise within the genome. They indicate that there is bias in the types of genes that con- tribute the most to functional innovation and evolution of complexity. As a direct re...

Ngày tải lên: 14/08/2014, 08:20

... Alternatively, the state of the CG4838_inv1 microinver- sion in D. willistoni may not be correct, and the inverted form may actually be present only in the pair of obscura group spe- cies. The latter ... each test, the number of trials equals the number of conserved orthologs per arm, the number of successes equals the number of event-harboring genes per arm,...

Ngày tải lên: 14/08/2014, 17:22

... storage of a single photon (SP) in the system consists of an emitter and a nanotip. The emitter is initially in the ground state jgi and the dipole moment p of the emitter is parallel to the axis of ... pulse and the emitter depends on the internal state of emitter after the storage. If the emitter is in the state jgi, the signal field is near, completel...

Ngày tải lên: 22/06/2014, 01:20

... products of the LONG type XVIII collagen are elevated in both the plasma and BALF of patients with ALI. Proteolytic cleavage of the carboxy end of collagen XVIII has been demonstrated for many enzymes ... alveolar neutrophilia and the extent of the loss of protein selectivity of the alveolar- capillary barrier. Plasma levels of endostatin correlated with t...

Ngày tải lên: 13/08/2014, 16:20