Báo cáo y học: "Traditional DMARD therapy: is it sufficient" potx

... inflammatory polyarthritis at five years. Arthritis Rheum 2003, 48:46-53. 25. Symmons D, Harrison B: Early inflammatory polyarthritis: results from the norfolk arthritis register with a review of the literature. ... Uffmann M, Smolen JS: Benefit of very early referral and very early therapy with disease-modifying anti-rheumatic drugs in patients with early rheumatoid arthritis. Rheumatology 2...

Ngày tải lên: 09/08/2014, 08:22

... Correlation of IL-6 with the classical humoral disease activity parameters ESR and CRP and with serum cortisol, reflecting the activity of the HPA axis in active rheumatoid arthritis. Z Rheumatol ... The American Rheuma- tism Association 1987 revised criteria for the classification of rheumatoid arthritis. Arthritis Rheum 1988, 31:315-324. Arthritis Research & Therapy Vol 5 No 4 Forsblad...

Ngày tải lên: 09/08/2014, 01:21

... of this pro- spective observational study (pilot and follow-up study), is shown in Table 4, incorporated in our hos- pital manuals and known to our hospital personnel. Finally, it may be true ... intestinal motility a) Severe obesity (BMI more than 28) b) Severe diabetes mellitus 4. Those who are at high risk of aspiration a) Those who have abnormality of recurrent lanryngeal nerve...

Ngày tải lên: 25/10/2012, 10:51

... tHcy has a positive effect on the hydroxyl methyl glutaryl -CoA synthase enzyme ( the rate limiting enzyme in cholesterol biosynthesis) and hence hypercholesterolaemia. Furthermore, they suggested ... Pathology, Medical Research Institute Hospital, Alexandria University, Egypt. 2 Internal Medicine (Cardiology Unit), Medical Research Institute Hospital, Alexandria University, Egypt. A...

Ngày tải lên: 03/11/2012, 09:49

... regulatory protein, antizyme inhibitor, a protein that displays homology t o ODC, but lacks d ecarb oxylating activity [19]. It binds to antizyme with higher affinity than ODC thus it may release active ... llular polyamines c omes from t heir synthesis from amino acid precursors. In this biosynthesis pathway ornithine is decarboxylated to form putrescine by the action of ornithine decar...

Ngày tải lên: 22/02/2014, 04:20

... activity is critical for C 2 -ceramide-induced apoptosis in PC12 cells Mutsuya Yamamoto, Takeshi Hioki, Takehisa Ishii, Sadayo Nakajima-Iijima and Shigeo Uchino* Pharmaceuticals Discovery Laboratory, ... and physiological or pathological neuronal cell death. However, it is not known whether DAP kinase activity is critical for neuronal cell death. Ceramide, generated by sphingomyelin h...

Ngày tải lên: 24/03/2014, 00:21

... pro- teinÆmL )1 with TEDS, stored at )20 °C and frozen-thawed once only for analyses. Guanylate cyclase activity Guanylate cyclase activity was quantified as described previously [24]. Brie y, 20 lg of ... cyclase C by a guanine nucleotide-dependent mechanism. Biochemistry 35, 3213–3221. 27. Desaubry, L., Shoshani, I. & Johnson, R.A. (1996) Inhibition of adenylyl cyclase by a family of new...

Ngày tải lên: 24/03/2014, 03:21

... peptide mapping analysis have established that Ser274 in p70 ik3-1 is phosphorylated by both cdk3/cyclin A and cdk3/cyclin E in vitro (Fig. 4). The same residue is also phosphorylated by both cdk3/cyclin A ... resembles the site in p53 which is phosphorylated by cyclin A/cdk2 [16]. We therefore asked whether this position is the phosphorylated Fig. 3. p70 ik3-1 is phosphorylated by...

Ngày tải lên: 24/03/2014, 04:21

... of improved flexibility. Patients were aware of an improvement in their cognitive flexibility qualitative feedback was generally positive towards CRT. Discussion: This preliminary study suggests that ... case reports, however, this preliminary exploration shows the following: This treatment was positively received by patients with a long history of AN and who had several attempts with psychol...

Ngày tải lên: 08/08/2014, 21:20