Báo cáo y học: "Relevance of the stroma and epithelial-mesenchymal transition (EMT) for the rheumatic diseases" docx

... where C 2 is the protein in the bulk, C 10 is the concentration inside the gel, S and V 1 are, respectively, the surface and the volume of film, V 2 is the volume of the bulk, h is the massive ... partially supported by the NINIVE (Non Invasive Nanotrans- ducer for In Vivo gene thErapy, STRP 033378) project, co-financed by the 6FP of the European Commission,...

Ngày tải lên: 22/06/2014, 00:20

... than for the TELDIR task; the reason is due to the very limited training data. One of the advantages of the ME approach re- sults from the property that the ME framework directly models the posterior ... be seen from these results, the ME models clearly outperform the alignment models. The quality of the translation approach is achieved within the ME framewor...

Ngày tải lên: 31/03/2014, 20:20

... biosyn- thetic pathways of tetrahydrofolate and tetrahydrobiopterin [3,4]. GTP cyclohydrolase II catalyzes the hydrolytic release of C8 of GTP accompanied by the release of pyrophosphate from the ... activity of the enzyme. The mutant proteins resulting from the replacement of any of the conserved cysteine residues in GTP cyclohydro- lase II with serine failed to...

Ngày tải lên: 23/03/2014, 21:20

... districts of the Southern California cities of Redlands and San Ber- nardino in the United States participated, 13.8% of the study participants reported having carried a weapon in the past 30 days. These ... participated in the interpretation of the results and drafting of the manuscript, ER conceived the analysis plan, conducted the statistical analyses and...

Ngày tải lên: 08/08/2014, 23:20

... number of inhabitants in each municipality and the degree of urbanisation of the municipality (rural, rural/urban or urban) were gathered from Statistics Nor- way. Information on the position of the ... this type of research may provide valuable information to advise policy makers and clinicians in their implementation and prioritisation of different types of inter...

Ngày tải lên: 08/08/2014, 23:21

... considered as candidates for interferon therapy as it was believed that in the setting of hepatic encephalopathy, ascites and protein malnutrition they would not tolerate therapy and also that their ... and the inability to achieve optimal dosing. Approximately 30% of patients will discontinue therapy. Often the only way of maintaining Int. J. Med. Sci. 2006, 3 79...

Ngày tải lên: 31/10/2012, 17:08

... 270) Ó FEBS 2003 enzyme inhibitory effect [4]. Therefore, the aim of the present work was to investigate the mode of action of the toxin, as part of a wider study to determine whether PA1b could ... (Diptera)larvaewereprovidedbyR.Allemand (UMR 5558 CNRS-UCBL, Lyon, France). Tests of toxicity The toxicity assays for PA1b or modified PA1b were performed on the S. oryzae s...

Ngày tải lên: 08/03/2014, 02:21

... 2002 Catalytic cycle of P-glycoprotein (Eur. J. Biochem. 269) 2675 UIC2, divided by the fluorescence intensity obtained in the absence of UIC2. In the case of the ÔUIC2 shift assayÕ [18], the cells ... conform- ational states. The consecutive steps of the catalytic cycle appear to be discriminated by the changing affinity of Pgp to the UIC2 mAb [18,30]. Reactivity o...

Ngày tải lên: 08/03/2014, 23:20

... than for the mixture of single enzymes. Apparently, a proximity effect or substrate channelling operates in the fusion enzyme and increases the overall catalytic activity of the reaction. The ... were obtained for the single FPPS and eAS as for the two fusion enzymes FPPS/eAS and eAS/FPPS and these K m were similar to those reported previously for FPPS and...

Ngày tải lên: 24/03/2014, 03:21