... group maintained at 37 o C. Additionally, normal karyotype was maintained in all low temperature-exposed groups, as assessed by fluorescence in situ hybridization (FISH) of metaphase spreads with ... (1–22 and X and Y) is painted a different color, using combinatorial labeling, so that any interchromosomal translocations are observed as color junctions on individual chromosom...
Ngày tải lên: 31/10/2012, 16:57
... biological meaning of these findings. But gene expression profiling of human erythrocyte could be an important key for under- standing the machinery of anucleate protein synthesis and its meaning ... DNA-binding proteins, cysteinyl, lysyl-tRNA syn- thetase), important RNA-stabilising factor - poly (A) binding protein, anti-apoptotic proteins (for instance beclin 1, reticulon 4...
Ngày tải lên: 03/11/2012, 10:58
Báo cáo Y học: Complexation of ytterbium to human transferrin and its uptake by K562 cells pot
... Arias, I.M. (1990) Serial quanti- tative image analysis and confocal microscopy of hepatic uptake, intracellular distribution and biliary secretion of a fluorescent bile acid analog in rat hepatocyte ... two Yb 3+ bind to apo-Tf in the specific iron binding site and two tyrosines are involved in binding of Yb 3+ in both the N- and C-lobe as the case for Fe 3+ . The X-ray cryst...
Ngày tải lên: 08/03/2014, 09:20
Báo cáo Y học: The a1b1 contact of human hemoglobin plays a key role in stabilizing the bound dioxygen Further evidence from the iron valency hybrids potx
... University, Hiroshima, Japan; 4 PHP Laboratory for Molecular Biology, Sendai, Japan When the a and b chains were separated from human oxyhemoglobin (HbO 2 ), each individual chain was o xidized easily ... Shikama, PHP Laboratory for Molecular Biology, Nakayama-Yoshinari 1-16-8, Sendai 989±3203, Japan. Fax: + 81 22 278 6180, E-mail: shikama@mail.cc.tohoku.ac.jp Abbreviations: p-MB, sodium...
Ngày tải lên: 31/03/2014, 15:20
Báo cáo Y học: Substrate specificity of human kallikrein 2 (hK2) as determined by phage display technology docx
... pentamer library. DNA sequence analysis reveal that an arginine appears in 40 clones at the P1 site and only one peptide is cleaved at a lysine. Among the substrates hydrolysed at an arginine, ... [8]. In addition, in vitro studies have shown that hK2 can activate urokinase-type plasminogen activator [9] and inactivate plasminogen activator inhibitor-1 [10] leading to the activation...
Ngày tải lên: 31/03/2014, 23:20
Báo cáo y học: "Chlamydia trachomatis Infection of Human Trophoblast Alters Estrogen and Progesterone Biosynthesis: an insight into role of infection in pregnancy sequelae." doc
... tested for mycoplasma contamination periodically by staining with 4,6 diamine-2-phenyl indole dihydrochloride (Boehringer, Mannheim, Germany). Chlamydia trachomatis culture Chlamydia trachomatis ... following chlamydia infection. The possibility of replicating these findings is the basis of an on-going in vivo study in our laboratory. Chlamydia trachomatis uniquely harbors eu...
Ngày tải lên: 08/08/2014, 16:23
Báo cáo y học: "Comparison between single antiplatelet therapy and combination of antiplatelet and anticoagulation therapy for secondary prevention in ischemic stroke patients with antiphospholipid syndrome"
... any difference in effectiveness for secondary preven- tion between single antiplatelet (aspirin) and single anticoagulant (warfarin) therapy. Our results indicate that combination therapy may ... (63 years) was significantly older than that in typical APS studies (34 years). Third, the target INR in WAPS [8] was for cardiogenic stroke caused by non-valvular Af. The dosage of aspir...
Ngày tải lên: 26/10/2012, 09:48
Báo cáo y học: "Thioglycosides as inhibitors of hSGLT1 and hSGLT2: Potential therapeutic agents for the control of hyperglycemia in diabetes"
... the inhibitory effect of some thioglycosides synthesized in our laboratory on human hSGLT1 and hSGLT2 –as a potential therapeutic alternative for the control of hyperglycemia, particularly for ... Dort- mund, Germany; 2. Max Planck Institute for Chemical Ecology, Dortmund, Germany Correspondence to: Francisco Castaneda, MD, Laboratory for Molecular Pathobiochemistry and Clinica...
Ngày tải lên: 26/10/2012, 10:04
Tài liệu Báo cáo Y học: Interallelic recombination is probably responsible for the occurrence of a new as1-casein variant found in the goat species potx
... GGC AGA GAA TAC GTT TAT ACT AA 3¢ C14L 5¢ TCT CAG ATT GAC TAC TAC AAC TT 3¢ C15U 5¢ CAT GAA AAG CAT TTC AAA AA 3¢ C15L 5¢ TAA AAA ACA GTG GTT ACC AA 3¢ C16U 5¢ CTA AAG AGT ACA CTA TCC TCA C 3¢ C16L ... amplification betweenC7UandC8L.Primersinitalicswereusedinthegenotyping of allele M. C1U 5¢ GAG AGG AAC TGA ACA GAA CAT TG 3¢ C1L 5¢ CAA CTG CGT ATT AGT GAA GAA TG 3¢ C2U 5¢ AAT CAA ATT TTA TTA...
Ngày tải lên: 22/02/2014, 04:20
Báo cáo Y học: Role of conserved residues within helices IV and VIII of the oxaloacetate decarboxylase b subunit in the energy coupling mechanism of the Na+ pump ppt
... of Y2 29, which subsequently can be replaced by a Na + -ion again, initiating the decarboxylation of the newly bound carboxybiotin. This interpretation can explain why in the S38 2A mutant decarboxylation ... recently that the initial velocity of oxaloacetate decarboxylation has sigmoidal dependence on Fig. 2. SDS/PAGE analysis of a selection of mutant oxaloacetate decar...
Ngày tải lên: 08/03/2014, 23:20