... APP within the Ab sequence, and its products are not neurotoxic. Alternatively, APP can be hydrolyzed by the b secretase activity at the N-terminus of Ab, which is successively released by the ... Bachem, Novabiochem or Fluka (Switzerland). The resin (4-hydroxymethylphenoxy- acetic acid) on the polyethyleneglycol/polystyrene support, loaded with N a -Fmoc-Ala (Fmoc-Ala-PAC-PEG-P...
Ngày tải lên: 08/03/2014, 09:20
... that there is a polyadenylation signal upstream of the poly(A). Analysis of the primary structure of M. brassicae Gqa The putative protein product encoded by the cloned cDNA was aligned with ... 2002 Recently, the a subunit of a G protein of the Gq family has been immunolocalized in olfactory sensilla preparations of the silkmoth Antherea pernyi [23]. Using immunocytol- ogy,...
Ngày tải lên: 17/03/2014, 23:20
Báo cáo Y học: A comparison of the urea-induced unfolding of apo¯avodoxin and ¯avodoxin from Desulfovibrio vulgaris potx
... stability of the holoprotein is smaller than the increase in stability that occurs with the a poprotein. As a con sequence, the stability of the apoprotein in high salt is greater than the s tability ... loops on one side of the molecule. The two methyl groups on the ¯avin are exposed to solvent, the dimethylisoalloxazine moiety is ¯anked by hydrophobic residues, an d t...
Ngày tải lên: 31/03/2014, 15:20
Báo cáo y học: "Special considerations in the treatment of patients with bipolar disorder and medical co-morbidities"
... medical conditions may be delayed. As the physician with the most (and often the only) contact with these patients, psychiatrists need to be vigilant in detecting early signs and symptoms of medical illness ... of patients with bipolar dis- order were obese. Pharmacotherapy and affective epi- sodes both influence appetite and physical activity, thereby increasing the risk for ob...
Ngày tải lên: 25/10/2012, 10:51
Báo cáo y học: "Subtyping patients with heroin addiction at treatment entry: factor derived from the Self-Report Symptom Inventory (SCL-90)" ppt
... factorial analysis, in the form of panic anxiety- related symptoms. Anxiety and panic anxiety may be linked with the withdrawal syndrome. The pathophysiol- ogy of withdrawal actually overlaps with that ... syndromes from the core psychopathology of addiction, and the overlap between the biological sub- strates and the neurophysiology of addictive processes and psychiatric sy...
Ngày tải lên: 08/08/2014, 23:21
Báo cáo y học: "Endovascular Treatment of Bilateral Carotid Artery Occlusion with Concurrent Basilar"
... carotid artery occlusion with concurrent basilar apex aneurysm. Brain blood supply was provided by the bilateral vertebral artery through the basilar artery. We treated the aneurysm with the endovascular ... artery and the artery underlying the cavernous sinus, and the external carotid artery through the ophthalmic, anterior ethmoid, and intracranial arteries. The one...
Ngày tải lên: 25/10/2012, 11:04
Báo cáo y học: " Experimental ablation of the pancreas with high intensity focused ultrasound (HIFU) in a porcine model"
... recovered rapidly. In the present study, the amylase levels in the serum and urine were increased in the first 3 days and the first 5 days after HIFU ab- lation, respectively. But no significant ... (×10000) at day 7 after HIFU. The cell membrane was completely destroyed, and ultrastructures could not be identified. Biochemistry parameters In the present study, the amyla...
Ngày tải lên: 25/10/2012, 11:18
Báo cáo khoa học: Lipopolyamine treatment increases the efficacy of intoxication with saporin and an anticancer saporin conjugate doc
... on protein synthesis. Interestingly, the degree of saporin sensitization correlated directly with the transfection efficacy of the lipopolyamine. By contrast, the three tested lipopolyamines did ... conjugates enter the target cell by endocytosis and then escape the endomembrane system to reach their cytosolic target [7–11]. Other toxins that follow this general pathway exit the...
Ngày tải lên: 07/03/2014, 05:20
Báo cáo Y học: Subsite mapping of the binding region of a-amylases with a computer program ppt
... is not hydrolysed by a-amylases therefore, the products of hydrolysis are always b-glycosides. Selection of these glycosides as substrates has been based on their size (DP 4–10) and good yields ... for barley a-amylase justify the ‘6 + 2 + (1) model’ prediction. Thebinding areaof barleya-amylase is composed ofsix glycone, two aglycone binding sites followed by a barrier subsite at the r...
Ngày tải lên: 08/03/2014, 09:20
Báo cáo Y học: Functional studies of the Synechocystis phycobilisomes organization by high performance liquid chromatography on line with a mass spectrometer docx
... a in the thylakoid membrane [5]. Phycocyanin is the major constituent of the phycobilisomes, while allophycoc yanin holds the bridging pigments between phycobilisomes and the photosynthetic lamellae ... to the PCa,PCb,APCa and APCb, respectively. PC, phycocyanin; APC, allophycocyanin. Ó FEBS 2002 Study of phycobilisomes organization by HPLC-ESI-MS (Eur. J. Biochem. 269) 1539 Synec...
Ngày tải lên: 08/03/2014, 16:20