Báo cáo y học: "Interleukin-15 and interferon-γ participate in the cross-talk between natural killer and monocytic cells required for tumour necrosis factor production" docx
Báo cáo khoa học: Hydrogen bond residue positioning in the 599–611 loop of thimet oligopeptidase is required for substrate selection pdf
... finding of this study is that the bradykinin analogue mcaBk can still be cleaved efficiently after removal of the Tyr hydroxyls of Y6 05 and Y6 12 from the wild-type form of the enzyme, thus making ... K m with the single Tyr mutant. Molecular modeling and molecular dynamics indeed suggest that the Tyr605 hydroxyl is in close proximity to the carbonyl of the scissile pep...
Ngày tải lên: 23/03/2014, 06:20
Báo cáo y học: "Antiviral therapy of HCV in the cirrhotic and transplant candidate"
... costly and has not been studied rigorously in a randomized controlled format to assess their value and impact on efficacy of therapy although they are now widely used in patients receiving interferon ... growth factors, specifically G-CSF and erythropoietin, has allowed more aggressive dosing of interferon and ribavirin. [13, 14] Finally, growing experience with antiviral t...
Ngày tải lên: 31/10/2012, 17:11
Báo cáo Y học: Identification of residues in the PXR ligand binding domain critical for species specific and constitutive activation docx
... human and mouse PXR ligand binding domains. By modeling the human PXR ligand binding domain we have identified and mutated two polar residues in the puta- tive ligand binding pocket which differ between ... °C for 45 min. For the amino-acid analysis an AminoQuant II/M High Sensitivity Instrument (Hewlett Packard, Waldbronn, Germany) was used. The AminoQuant amino-acid analyz...
Ngày tải lên: 08/03/2014, 16:20
Báo cáo y học: "Complications after spacer implantation in the treatment of hip joint infections"
... Despite the retrospective study design and the limited possibility of interpreting these find- ings and their causes, this rate indicates that patients suffering from late hip joint infections and ... approximately 10 %. Interestingly, the majority of the cases had no symptoms at all and only in 2 cases the spacer had to be exchanged in an additional surgery. For p...
Ngày tải lên: 26/10/2012, 09:53
Báo cáo Y học: Role of tyrosine 238 in the active site of Rhodotorula gracilis D-amino acid oxidase A site-directed mutagenesis study docx
... the wild-type enzyme but the degree of stabilization of the flavin semiquinone and the redox properties in the free form of Y2 38S are different. The binding of the carboxylic acid competitive inhibitors ... measured by the dye equilibration method of Minnaert [17], in order to assess changes in the thermodynamic properties of the flavin centre caused by the mutati...
Ngày tải lên: 17/03/2014, 17:20
Báo cáo toán học: " A new approach to investigate the interactions between sediment transport and ecotoxicological processes during flood events" ppt
... of the article and gave their final approval. All authors read and approved the final manuscript. Competing interests The authors declare that they have no competing interests. Received: 9 May ... effective- ness in both in vi tro and in vivo systems) (Figure 1). Therefore, this methodolog y presents considerable advantages for a better understanding and description of...
Ngày tải lên: 20/06/2014, 21:20
Báo cáo y học: "Is there a dysfunction in the visual system of depressed patients" pptx
... assessment and diagnosis. In no case medication was interrupted in order to include the patient in the study. 2. Be physically healthy with normal clinical and labora- tory findings, including EEG, ... conditions). The procedure includes recordings of eye movents every 2 minutes, for 12 minutes in dark and subsequently 12 minutes in light. The resulting recording is...
Ngày tải lên: 08/08/2014, 21:20
Báo cáo y học: "A prospective observational study of the relationship of critical illness associated hyperglycaemia in medical ICU patients and subsequent development of type 2 diabetes"
... almost certainly include pre-existing increased insulin resistance and dysfunction of beta cells. Insulin resistance is present in the acutely ill [13,15,18,28] in different intensity, but the factors ... normoglycaemia group and 93 in the hyperglycae- mia group who discontinued their assessments. Also, we stopped the follow-up for 15 patients in the normogly- caemia...
Ngày tải lên: 25/10/2012, 10:02
Báo cáo y học: "Management of chest pain: exploring the views and experiences of chiropractors and medical practitioners in a focus group interview"
... training or opportunity, yet this rep- resents the one area beyond the standard curriculum where further training can be gained and is therefore the only way in which current chiropractors may ... set of themes as reached via consensus. This process involved examining themes for commonal- ity, classifying them for uniformity, and then reaching agreement on the final list of...
Ngày tải lên: 25/10/2012, 10:06
Báo cáo y học: "Mirror-Image Arachnoid Cysts in a Pair of Monozygotic Twins: A Case Report and Review of the Literature"
... es- calated in AC and NKCC1 was present in the AC wall. These finding indicated NKCC1 gene might play an important role in cystogenesis. The association of AC and other diseases in families ... AC in the other twin (twin B), when the concerned parents took him to our department. Brain CT and MRI of twin B who did not have any com- plaints revealed a mirror-imaging...
Ngày tải lên: 25/10/2012, 11:00