... the protein without seriously affecting the substrate binding affinity. Binding analyses using BIAcore system To examine whether the mutation of Gly10 to Leu or Pro affects the substrate binding ... models, in which the oxygen atoms are shown in red. The side chain of Tyr170 is also illustrated by a blue stick model. The main chain of Gly10 is shown in red. N, N-termi...
Ngày tải lên: 17/03/2014, 17:20
... objective was to investigate the validity of the MyMOP2 instrument to detect a change in well-being of patients attending the RMIT chiroprac- tic teaching clinic. The mean baseline MYMOP2 profile score ... delivered by student chiropractors in a clinical teaching facility. The W-BQ12 was also used as a tool to assess the validity of the well being component of the...
Ngày tải lên: 25/10/2012, 10:06
Báo cáo y học: "Impact of the Kenya post-election crisis on clinic attendance and medication adherence for HIV-infected children in western Kenya"
... (Eldoret, Kenya) and the Institutional Review Board of the Indiana University School of Medicine (Indianapolis, Indiana). Informed consent was obtained for key informant inter- views, and all clinical investigation ... Manager in the Department of Med- icine, Indiana University School of Medicine. PB is an Assistant Professor of Medicine at the Indiana University School o...
Ngày tải lên: 25/10/2012, 10:31
Báo cáo y học: "Evaluation of the Prevalence of Concomitant Idiopathic Cyclic Edema and Cellulit"
... other causes of edema were excluded. The diagnosis of idiopathic cyclic edema was based on a clinical history and fluid retention throughout the day, in particular difficulty in removing rings ... waking in the morning which improves later in the day. All patients with cyclic edema were treated with 75 mg aminaphtone three times daily. Statistical analysis con- sidered...
Ngày tải lên: 25/10/2012, 10:51
Báo cáo y học: "Enhancement of the Click Chemistry for the Inverse Diels Alder Technology by Functionalization of Amide-Based Monomers"
... the cor- responding tetrazine 6, which in turn reacts with a mixture of the dansyl derivative and the N-ethyl-diisoproylamine and the dansyl sulfamidoethylamine to the tetrazine product 7 linked ... glycine’s N-terminus, as originally described by Nielsen in the protocols for the synthesis of the peptide nucleic acid (PNA) backbone [29, 30]. We synthesized and inv...
Ngày tải lên: 25/10/2012, 11:00
Báo cáo y học: " Efficacy of the Valsalva Maneuver on Needle Projection Pain and Hemodynamic Responses During Spinal Puncture"
... Statistical analysis In a pilot study of 20 patients having spinal an- esthesia by 25-guage Quincke needle, 90% of them had moderate to severe pain using NRS (unpublished observation). Presuming that ... obtund pain of needle insertion including infiltration analgesia and EMLA patch. Local anesthetics themselves may pro- duce pain on injection and many anesthetists are un- sure th...
Ngày tải lên: 25/10/2012, 11:15
Báo cáo y học: "Extension of the PNA world by functionalized PNA monomers eligible candidates for inverse Diels Alder Click Chemistyr"
... to the final product 9 is the tert-butyl protected 3-[(2-aminoethyl)amino]glycine 8. Details of the synthesis protocol are shown in the footnote. 1 1 tert-butyl 3-[(2-aminoethyl)amino]glycine: ... described in the footnote 4 . This device works in a variety of ligation areas which will be described in the following. Synthesis of PNA polymers Using the s...
Ngày tải lên: 26/10/2012, 08:57
Báo cáo y học: "Association of the T+294C polymorphism in PPAR δ with low HDL cholesterol and coronary heart disease risk in women"
... state the activities of numerous interacting genes are altered which may influence the effect of PPARδ on metabolism. In our data and in the study by Skogsberg et al., the effect of the C ... by silver staining on polyacrylamid gel. Statistical Analysis Allele frequencies were determined by gene counting and compared using the א² test. The data was analysed usi...
Ngày tải lên: 31/10/2012, 17:03
Báo cáo y học: "Study of the early steps of the Hepatitis B Virus life cycle"
... The progeny HBV both in the medium and in the cytosol were examined. By 3 days after the inoculation, the amount of HBsAg in the culture medium fell below the level of detection. However, the ... binding could be inhibited by recombinant HBs but not by the recombinant LHBs. The binding of SHBs with human hepatocytes was further supported by the observatio...
Ngày tải lên: 03/11/2012, 10:09
Tài liệu Báo cáo Y học: Inactivation of the 2-oxo acid dehydrogenase complexes upon generation of intrinsic radical species pptx
... appearance of the ThDP adduct with the substrate moiety during the complex-catalyzed succinyl-CoA hydro- lysis [72] accounts for the inactivation by dihydrolipoamide in the presence of succinyl-CoA ... network of interacting lipoyl moieties of the E2 core provides a good explanation for these phenomena. Considering possible mechanisms of the inactivation of the c...
Ngày tải lên: 21/02/2014, 01:21