Báo cáo khoa học: "Segmental resection of the duodenum for gastrointestinal stromal tumor (GIST)" ppt

... [2]. Therefore, the age of our patient is quite untypical for the diagnosis of duo-denal GIST.GISTs of the duodenum make up only 4.5% of all GISTs[12] and therefore represent a rare tumor ... occurredsince the emergency ligation of tumor- feeding vessels.A relaparotomy was performed. The tumor was located in the proximal third portion of the duodenum, 3 cm distal of the ampulla of Vater ... available on the choice of surgicalprocedures for duodenal GIST. For small tumors, localwedge resection of the duodenum is feasible. For smallergastric GISTs, wedge resection instead of gastrectomyseems...

báo cáo khoa học: "Isolated angiitis of the central nervous system with tumor-like lesion, mimicking brain malignant glioma: a case report and review of the literature" pdf

... informed consent was obtained from the patient for publication of this Case report and any accompany-ing images. A copy of the written consent is available for review by the Editor-in-Chief of ... s of IACNS in which he emphasized the importance of cerebral angiography and biopsy based oncareful exclusion of other diseases. When cerebralang iography sh ows stenosis or occlusion of the ... been performed in patients withIACNS, nor is it possible to dra w firm conclusions fr om the current study because of the non-standardized nat-ure of the treatment protocols used in these cases.Fountain...

Báo cáo khoa học: "A Bag of Useful Techniques for Efficient and Robust Parsing" ppt

... normal form (DNF). Of course, the ratio of the number of rules and lexical entries in the original grammar and the DNFed grammar depends on the 'style' of the grammar writer, the particular ... of entries) require the existence of other items such that the non-existence of one allows a safe deletion of the other (and vice versa). In Ger- man, for instance, prefix verbs require the ... unification. Therefore, any improvements in the efficiency of unification would have direct conse- quences for the overall performance of the sys- tem. One key to reducing the cost of unification...

báo cáo khoa học: "Surgical outcome of hepatocellular carcinoma patients with biliary tumor thrombi" ppt

... invade the walls of the large bile ducts around the hepatichilus. Therefore, liver resection of the involved hepaticsegments with thrombectomy through a choledochot-omy is a rational technique for ... lack of ef fectivealternative therapies. Further studies are needed for understanding of molecular biology of BTT may yieldtherapeutic tools that can improve the prognosis of thissubset of patients.ConsentWritten ... partia l resection (n = 6). The BTT were removed by the chole dochotomy in 18 cases,from the cut end of the bile duct after liver resection infive c ases, and en bloc removal with the primary tumor in...

Báo cáo khoa học: "Curative resection of a primarily unresectable acinar cell carcinoma of the pancreas after chemotherapy" docx

... literature, operative resection of the tumor seems to be the only curative treatment of ACC [1,2,4,12].Therefore, if an ACC is assumed or histologically proven, the chances for total resection should ... Bulky tumor masses were found toinfiltrate the hepatoduodenal ligament, the interaorto-caval space and the venous confluens of the superiormesenteric and the portal vein. The ACC was thereforedetermined ... resection of an ACC. Comparison of the histology of the biopsy and the surgical specimen showed large differ-ences, because after chemotherapy there were necroticareas, and the vital tumor tissue...

Tài liệu Báo cáo khoa học: Crystal structure of the cambialistic superoxide dismutase from Aeropyrum pernix K1 – insights into the enzyme mechanism and stability pdf

... counted the interactions, we excluded all residuesinvolved in the binding of the metal cofactor.ApeSODs in different forms were superimposed with the least square ﬁt of Ca atoms of the residues ... ligand,NE2 of His31, bound to the metal, in the company of a water oxygen, from the apical positions. The manga-nese was only 0.06 A˚out of the equatorial plane(Table 3). The angles around the metal ... additional water oxy-gen, which, together with the OD2 of Asp165, the NE2 of His79 and the NE2 of His169, formed anequatorial plane (Fig. 3B). The metal ion and the addi-tional water oxygen were...

Tài liệu Báo cáo khoa học: Homologous expression of the nrdF gene of Corynebacterium ammoniagenes strain ATCC 6872 generates a manganese-metallocofactor (R2F) and a stable tyrosyl radical (Y•) involved in ribonucleotide reduction ppt

... RNR and that of other class 1RNRs or, instead, is a result of the interaction of the R2F with the inactivated (oxidized) form of the R1E.We consider the ﬁrst option unlikely. Under these cir-cumstances, ... from the tyrosyl rad-ical (Y122) of the R2 subunit to the cysteine (C439)found in the active site of the R1 subunit; (b) the abstraction of two protons and water release, with the concomitant formation ... in the present study. Rather, the involvement of manganese in the in vivo assembly of the metallocofactor of C. ammoniagenes R2F is envis-aged. This is based: (a) on the parallel enrichment of manganese...

Tài liệu Báo cáo khoa học: Crystal structures of the regulatory subunit of Thr-sensitive aspartate kinase fromThermus thermophilus pdf

... in the absence of Thr [20]. Therefore, a sim-ilar conformational change is expected for these twoenzymes, depending on the presence or absence of Thr.In CgAK, mutations of the residues in the ... regulatory mechanism of Thr and the struc-tural features responsible for the high thermostability of TtAKb.Results and DiscussionModel quality The crystal structure of the Thr-bound form of TtAKb(TtAKb-Thr) ... binding shifts the equilibrium to dimer formation. In the absence of Thr, an outwardshift of b-strands near the Thr-binding site (site 1) and a concomitant loss of the electron density of the loop...

Tài liệu Báo cáo khoa học: Limited suppression of the interferon-b production by hepatitis C virus serine protease in cultured human hepatocytes pptx

... lgÆmL)1) for 6 h before the sampling for RNA preparation. Quantitative RT-PCR analysis for IFN-bmRNA was performed as described in (C). The IFN-b mRNA level was calculated relative to the level in the ... PH5CH8 cells. First, weconﬁrmed the effect of NS3-4A on the activation of the IFN-b gene promoter by the Cardif exogenouslyexpressed in PH5CH8 cells. The results of the lucif-erase reporter assay ... reporter) and cultured for 42 h, and thenpoly(I-C) (1 lg) was transfected into the cells for 6 h before the reporter assay as described in the Experimental procedures. The relativeluciferase...

Tài liệu Báo cáo khoa học: Kinetic characterization of the ﬁrst step of the ribozyme-catalyzed trans excision-splicing reaction docx

... to (if not the same as) the role of the xG in the second step of self-splicing [48–56].This suggests that the guanosine to be excised islikely binding to the GBS of the ribozyme for the exon-ligation ... that there is room for improve-ment in terms of the rate of reaction. This would bebeneﬁcial not so much in terms of the rate of the over-all reaction, as the cleavage reaction is not the limitingstep ... product. Therefore, the amount of product formed during the chase period isrepresentative of the amount of ribozyme–substratecomplex formed during t1. Note, however, that ifk)1$ k2, then...

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