Báo cáo khoa học: "The Merendino procedure following preoperative imatinib mesylate for locally advanced gastrointestinal stromal tumor of the esophagogastric junction" ppsx

... Oncology Open Access Case report The Merendino procedure following preoperative imatinib mesylate for locally advanced gastrointestinal stromal tumor of the esophagogastric junction Wilko I ... with a locally advanced GIST of the GEJ who was first treated by imatinib mesylate followed by tumor removal with limited resection and interposition of...

Ngày tải lên: 09/08/2014, 07:21

... of the V max value of the wildtype enzyme. The R201A, N203A, E206A and M208A enzymes had V app values similar to the V max value of the wildtype. The K m values for ATP varied somewhat, but the values ... with the triphosphate chain of ATP either directly or indirectly through the Mg 2+ ion chelated to the phosphate chain of the MgATP complex or it might form...

Ngày tải lên: 23/03/2014, 15:20

... [38], increasing the NUE. Resorption is the repeated use of the same nutrient units and could therefore be a good means of estimating the efficiency of nutrient use; nevertheless resorption ... biomass production per unit of absorbed nutrient is simply the inverse of the concentra- tion of the nutrient in question in the tissues of...

Ngày tải lên: 08/08/2014, 14:21

... both in the phloem and the sapwood in response to bark inoculation. They may therefore, together with the development of the fungus, have a negative impact on the water conducting ability of the ... potential. The most striking result was the significant but non- linear relationship between the amount of damage and the loss of conductivity; the latter increasing...

Ngày tải lên: 08/08/2014, 14:22

... prognosis. For exam- ple in case of a liposarcoma neoadjuvant treatment seems to be the therapy of choice and not primary extensive sur- gery. In our case the intraoperative detection of the macroscop- ically ... and the importance of the surgeons' intraoperative judgement of the tumour, concerning an unknown primary tumour located in the adrenal gland and the...

Ngày tải lên: 09/08/2014, 07:21

... types is, the headword of the current node (type1), the headword of the parent node (type2), the headword of the grandpa node (type3), the first word in the objective word sequence(type4), the first ... brother of the current node 0.5832 2.1511 1.2186 Y= the second right brother of the current node 0.1066 0.5044 0.2525 Y= the second left brother of the...

Ngày tải lên: 20/02/2014, 18:20

... regulation of the three thyroid cell lines We investigated the effects of XCT790, a specific inverse agonist of ERRa. As controls of the inhibitory effect of XCT790 on ERRa, we used the expression of ERRa-validated ... study, we looked for the effect of the ERR a–PRC complex 48 h after overexpression of PRC and ERRa. We suspect that a further period of treatment...

Ngày tải lên: 06/03/2014, 09:22

... the DOCK function of moe. The initial 3D structures of the ligands were con- structed using the BUILDER function in the moe program. The initial positions of these compounds were set within the ... further understand the structure–potency relation- ship of the FAS inhibitory peptides, we examined the relationships between the physicochemical and biochemical featu...

Ngày tải lên: 06/03/2014, 09:22

... and p is the probability p(a | f) estimated by the training process. 3. Order the set of triples by the value of p, with the largest probabilities first. Call the ordered set T . 4. Remove the highest-ranked ... 2) where N f is the number of occurrences in the train- ing data of utterances with feature f, and N a f is the number of occurrences of utterances with...

Ngày tải lên: 17/03/2014, 06:20

... suggested that the size of the resulting ring and the preorganization of the substrate determine whether a ligation or a cyclization step is carried out [39]. Unfortunately, the prefold of the lin- ear ... enable the specific angle, following the Bu ¨ rgi–Dunitz trajectory, required for the nucleophilic attack onto the acyl-O-TE oxo- ester intermediate [36]. Furth...

Ngày tải lên: 23/03/2014, 06:20