... IM, Maliszewski CR: Anti -cytokine < /b> antibodies as carrierproteins. Prolongation of < /b> in vivo effects of < /b> exogenouscytokines by < /b> injection of < /b> cytokine-< /b> anti -cytokine < /b> antibodycomplexes. J Immunol 1993, ... [7,8],inflammation and cartilage degradation were inhibited by< /b> blocking IL-1β but not IL-1α. In RA patients, IL-1β is over-expressed in inflamed synovial tissue, in particular in the lininglayer and in sublining ... evaluated at baseline and on days8, 15, 22, 29 and 43 by < /b> the investigator, and at baseline and day 43 by < /b> a blinded observer at each site who was not other-wise involved in the study. Overall,...