Báo cáo y học: "Expression of the inflammatory chemokines CCL5, CCL3 and CXCL10 in juvenile idiopathic arthritis, and demonstration of CCL5 production by an atypical subset of CD8+ T cells" pps
Báo cáo y học: "Expression of the inflammatory chemokines CCL5, CCL3 and CXCL10 in juvenile idiopathic arthritis, and demonstration of CCL5 production by an atypical subset of CD8+ T cells" pps
... upon three chemokines, namely CCL5, CXCL10 and CCL3, which are potential novel therapeutic targets in arthritis. The aim of the study was to analyse the expression and production of these three chemokines ... expressed CCL5 protein (Figure 6). In addition, staining was demonstrated at the synovial lining and on many infiltrating inflammatory cells. Protei...
Ngày tải lên: 09/08/2014, 07:20
Báo cáo Y học: Substrates modulate the rate-determining step for CO binding in cytochrome P450cam (CYP101) A high-pressure stopped-flow study pdf
... accumulated indica- ting that the dynamics of the protein structure and in particular the accessibility of the active site for water molecules are very important [3]. In the oxidized form of P450 the ... nature of the ligand indicating two main steps, the iron-ligand bond formation (negative DV # ) and the entry of the ligand into the protein (positive...
Ngày tải lên: 08/03/2014, 23:20
Báo cáo y học: "A crucial role for tumor necrosis factor receptor 1 in synovial lining cells and the reticuloendothelial system in mediating experimental arthritis" pps
... contributed to the study design, statistical and data analysis, interpretation of data, and drafting of the manuscript. WBvdB conceived of the study and helped draft the manuscript. All authors ... acquire data and contributed to the study design, statistical and data analysis, interpretation of data, and drafting of the manuscript. SV, BTvdB, and MBB helpe...
Ngày tải lên: 12/08/2014, 12:20
Báo cáo y học: " First Dominique Dormont international conference on "Host-pathogen interactions in chronic infections – viral and host determinants of HCV, HCMV, and HIV infections" pdf
... sug- gesting that long-term transmission is associated with rep- lication in DC rather than with the retention of infectious particles through DC-SIGN. The fusion step of entry After interaction of the ... activity and infectivity. Interestingly, HIV-1 mutants escaping the effects of the fusion inhibitor T- 20 frequently present variations in amino acid 36 of gp41....
Ngày tải lên: 13/08/2014, 09:21
Báo cáo y học: "CD4+CD25+ immunoregulatory T cells may not be involved in controlling autoimmune arthritis" ppsx
... authors thank Ms S Velins for assistance in the preparation of this manuscript. This work was supported in part by grants from the National Institutes of Health (AR45652 to KM and AF; AR47412 and AR49047 ... constitutively express cytotoxic T- lymphocyte antigen (CTLA)-4 [6–8], fail to proliferate or secret cytokines in response to polyclonal or antigen-spe- cific stimula...
Ngày tải lên: 09/08/2014, 01:21
Báo cáo y học: " Proinflammatory cytokine responses induced by influenza A (H5N1) viruses in primary human alveolar and bronchial epithelial cells" ppt
... were not signifi- cantly different (Figure 4C). Induction of pro -inflammatory cytokines and chemokines in type II pneumocytes We investigated the cytokine induction profile induced by H1N1 and ... viruses, it is pertinent to investigate the cytokine induction profile of H5N1 viruses in these cells. Methods: We used quantitative RT-PCR and ELISA to compare the profile...
Ngày tải lên: 12/08/2014, 18:20
Báo cáo y học: "Transpulmonary thermodilution-derived cardiac function index identifies cardiac dysfunction in acute heart failure and septic patients: an observational study" pptx
... out the statis- tical analysis, contributed to the interpretation of data, and drafted and revised the manuscript. AR carried out the statis- tical analysis, contributed to the interpretation of ... calculates CO by the modified Stewart-Hamilton equation, the mean transit time (MTt), and the exponential downslope time (DSt) of the curve. The product of CO t...
Ngày tải lên: 13/08/2014, 18:22
Báo cáo y học: "Methotrexate enhances the anti-inflammatory effect of CF101 via up-regulation of the A3 adenosine receptor expression" doc
... examined the mode of action of MTX. It acts as an antagonist of folic acid, subsequently inhibiting the synthesis of purines and pyrimidines. It was further sug- gested that the anti -inflammatory ... designated the standard. The blots were quantified by densitometric analysis and the ratio of RA patient/standard was calculated. Blots of mitogen stimulated cel...
Ngày tải lên: 09/08/2014, 08:23
Báo cáo y học: " Expression of S100A8 correlates with inflammatory lung disease in congenic mice deficient of the cystic fibrosis transmembrane conductance regulator" pps
... mice Competing interests The author(s) declare that they have no competing inter- ests. Authors' contributions ST performed the majority of the studies, particularly the lung dissection, quantitative ... S100 family of the EF hand calcium-binding proteins [56]) that are expressed principally, constitutively and coordinately by circulating neutrophils and monocytes but...
Ngày tải lên: 12/08/2014, 16:20
Báo cáo y học: "Expression of hMSH2 protein of the human DNA mismatch repair system in oral lichen planus"
... omission of the primary or the secondary antibody or primary incubation in the presence of non-immunized rabbit serum instead of the primary antibody. Cell quantification and Statistical analysis ... undergoing rapid renewal: in the lower-two thirds of gastrointestinal glands [15], in the more primitive testicular germ cells [28], in the transitional epith...
Ngày tải lên: 03/11/2012, 09:54