Báo cáo y học: "Methotrexate in rheumatoid arthritis is frequently effective, even if re-employed after a previous failure" potx

... and DA were involved in designing the study, analyzing the data, and drafting the manuscript. TS, KPM and KM were involvement in data acquisition. References 1. Graudal NA, Jurik AG, de Carvalho ... monitoring, comedication and even the increasingly employed paradigm to change therapy if a state of low disease activity is not reached within few months [16,17] – re-prescribing meth...

Ngày tải lên: 09/08/2014, 07:20

... growth factor in synovial tissue from patients with rheumatoid arthritis and degenerative joint disease. Lab Invest 1995, 73:339-346. 30 Yamashita A, Yonemitsu Y, Okano S, Nakagawa K, Nakashima Y, Irisa ... in a single gene, post-translational mod- ification by glycosylation and glycosaminoglycan (GAG) attachments further modifies the CD44 protein, allowing greater expansion of...

Ngày tải lên: 09/08/2014, 01:21

... protein is important in containing and repairing Arthritis Research & Therapy Vol 6 No 6 Hitchon and El-Gabalawy 271 [77]. This study demonstrated that the regulation of glycolytic capacity by ... S: Expression and localization of vascular endothelial growth factor-C in rheumatoid arthritis synovial tissue. J Rheumatol 2002, 29:34-38. 95. Kasama T, Shiozawa F, Kobayashi K, Yaj...

Ngày tải lên: 09/08/2014, 01:24

... hypothalamus-pituitary-adrenal axis by pro- inflammatory stimuli and chronic stress leads to a parallel decrease in hypothalamus-pituitary-gonadal axis activity [2,11]. This can be substantiated ... inversely correlated with both disease duration and clinical severity in patients already affected by active RA. In particular, gonadal and adrenal androgens (that is, testosterone and DH...

Ngày tải lên: 09/08/2014, 14:22

... resulted in a marginal increase of RASFs arrested in G 2 /M phase (~4 n DNA at G 2 /M peak, black line, representative histogram). (b) Quantitative analysis. Values are mean ± stand- ard deviation as ... A, Drynda A, Mendoza H, Gay RE, Hay RT, Ink B, Gay S, Pap T: Mod- ification of nuclear PML protein by SUMO-1 regulates Fas- induced apoptosis in rheumatoid arthritis synovial...

Ngày tải lên: 09/08/2014, 01:22

... (Th1)-driven disease [5]. This cell type plays a key role in the pathogenesis of many rodent models of arthritis, including collagen-induced arthritis, antigen-induced arthritis, and adjuvant arthritis, ... Reduction of synovial inflammation after anti-CD4 monoclonal antibody treatment in early rheumatoid arthritis. Arthritis Rheum 1995, 38:1457-1465. Available online http:...

Ngày tải lên: 09/08/2014, 06:23

... disease activity. As indicated in the present study JIA disease activity, as indicated by laboratory parameters of inflammation (hemoglobina, leucocyte count and ESR), is an important risk factor ... obtained by review of follow-up visits and by stand- ardized telephone interviews. Statistical analysis was done by χ 2 test and linear multiple discriminant analysis for categorial data and...

Ngày tải lên: 09/08/2014, 10:20

... Switzerland). Results Xanthurenic acid modifies the Boc-amino acids lysine, arginine, histidine, and glutamine The Boc modification of amino acids blocks its primary amino group, and the secondary amino group of amino acids ... 9 nicotine amide or, alternatively, xanthurenic acid. Kynur- enine aminotransferase (KAT) is the enzyme leading to the alternative pathway of xanthurenic acid format...

Ngày tải lên: 10/08/2014, 05:21

... biopsy shows an acute inflammation in the lamina propria, consisting of an increase in polymorphonuclear cells. The neutrophils infiltrate the mucosa, leading to crypt abscess (arrowhead), flattened ... lymphocytes). While being investigated, the patient had a life-threatening hematochezia. After angiographic occlusion of a branch of the ileocaecal artery and initiation of antiretro...

Ngày tải lên: 11/08/2014, 03:21

... consent is available for review by the Editor -in- Chief of this journal. About Authors Ms Stella Smith is a Specialist Registrar in General Surgery. Mr Moayad Aljarabah is a Registrar in General Surgery. ... thigh as a donor site. On day 13 her wound was inspected, revealing that >90% of the graft had taken and there was no clinically apparent infection. Oral antibiotic th...

Ngày tải lên: 11/08/2014, 12:20