Báo cáo y học: "CD147 overexpression on synoviocytes in rheu

Báo cáo y học: "CD147 overexpression on synoviocytes in rheumatoid arthritis enhances matrix metalloproteinase production and invasiveness of synoviocytes" pptx

... zymography of culture medium conditioned by fibroblast-like synoviocytes (FLS) and monocytes/macrophagesGelatin zymography of culture medium conditioned by fibroblast-like synoviocytes (FLS) and monocytes/macrophages. ... proliferating mass of synoviocytes locally invades the cartilage and bone, destroy- ing the joint. MMPs, mainly produced in FLS, play a central role in...

Ngày tải lên : 09/08/2014, 07:20

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Báo cáo y học: "Targeting histone deacetylase activity in rheumatoid arthritis and asthma as prototypes of inflammatory disease: should we keep our HATs on" pps

... perpetuation and progression in RA [2]. Studies addressing the acetylation status of signaling proteins, and consequences of changes in protein acetylation for cellular activation and survival in RA synovial ... pathways Activation of JAK kinases and subsequent stimulation of transcriptional activity of the STAT family of transcription factors is one of the main si...

Ngày tải lên : 09/08/2014, 11:20

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Báo cáo y học: "Randomized controlled trial design in rheumatoid arthritis: the past decade" docx

... combination therapy only during the second 6 months. Recognition of similar irreversible losses in physical function in other trials fortunately has resulted in a more limited use of placebo and ... parenteral administration, including rapid onset of effect, infusion, and injection site reactions, which may result in expectation bias as well as unblinding. Most importantly,...

Ngày tải lên : 09/08/2014, 01:22

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Báo cáo y học: "Apolipoprotein A-I infiltration in rheumatoid arthritis synovial tissue: a control mechanism of cytokine production" pot

... cells in these areas [15]. Conclusion In conclusion, the localization of apoA-I in inflamed syn- ovium suggests that it can locally inhibit the production of proinflammatory cytokines by monocyte–macrophages upon ... pathogenesis of rheumatoid arthritis (RA). Apolipoprotein A-I (apoA-I) blocks contact-mediated activation of monocytes, causing inhibition of TNF-α and IL...

Ngày tải lên : 09/08/2014, 01:24

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Báo cáo y học: "NGR1 single nucleotide polymorphisms in rheumatoid arthritis" pdf

... primer). Results and discussion In marked contrast to previous findings, no polymorphic alleles (neither thymine at position 40 nor cytosine at position 1,400) were detected in any of the individuals ... sur- prising because both positions were highly polymorphic in the original publications. In those publications, heterozygosity at position 40 (V14M) was detected in four indivi...

Ngày tải lên : 09/08/2014, 07:20

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Báo cáo y học: "Remission by composite scores in rheumatoid arthritis: are ankles and feet important" pptx

... clinical information, the inclusion of ankles and feet only rarely influences the definition of overall disease activity status, especially the presence or absence of remission. Composite indices ... classification into remission. Thus, by indices that employ the 28-JC, there is only a very small number of patients in remission who have joints involved that are not contained in...

Ngày tải lên : 09/08/2014, 10:20

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Báo cáo y học: "The need for prognosticators in rheumatoid arthritis. Biological and clinical markers: where are we now" potx

... Active-Controlled Study of Patients Receiv- ing Infliximab for the Treatment of Rheumatoid Arthritis of Early Onset Study Group: Combination of infliximab and methotrex- ate therapy for early rheumatoid arthritis: ... markers of disease activity Cells and cytokines The clinical manifestations of RA are the consequences of synovial inflammation and the subsequent deg...

Ngày tải lên : 09/08/2014, 10:23

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Báo cáo y học: " Partial-thickness macular hole in vitreomacular traction syndrome: a case report and review of the literature" pps

... vitreomacular traction syndrome. The relief of traction by vitrectomy restores foveal anatomy and visual acuity in this condition. Introduction Vitreomacular traction syndrome results in many com- plications, ... 20/60, and OCT findings like the presence of intraretinal cysts and retinal pigment epithelial detachment in addition to thick eccentric traction. Underlying retinal...

Ngày tải lên : 11/08/2014, 14:21

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Báo cáo y học: "Anticitrullinated protein antibody (ACPA) in rheumatoid arthritis: influence of an interaction between HLA-DRB1 shared epitope and a deletion polymorphism in glutathione s-transferase in a cross-sectional study" ppt

... cohorts including SONORA [37], which found no evidence of interaction between SE and ever smoking in S ONOR A and only weak evidence of interaction in one of the two other cohorts examined. In these ... positivity is increasingly recognized as a distinct disease phenotype in RA. Indeed, the well- defined associations of cigarette smoking and HLA- DRB1 SE with RA in Eur...

Ngày tải lên : 12/08/2014, 15:22

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Báo cáo khoa học: Kinetic studies on endo-b-galactosidase by a novel colorimetric assay and synthesis of N -acetyllactosamine-repeating oligosaccharide b-glycosides using its transglycosylation activity pptx

... Karlsson, K.A. (1996) Recognition of glycoconjugates by Helicobacter pylori: an apparently high-aﬃnity binding of human polyglycosyl- ceramides, a second sialic acid-based speciﬁcity. Glycoconj. ... substrate recognition at theactivesiteintheenzyme. Generally, glycosidase has transglycosylation activity as a reverse reaction of hydrolysis. Taking into account the hydrolytic action of...

Ngày tải lên : 31/03/2014, 07:20

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