Báo cáo y học: "CD95-induced osteoarthritic chondrocyte apoptosis and necrosis: dependency on p38 mitogen-activated protein kinase" ppsx
Báo cáo y học: "CD95-induced osteoarthritic chondrocyte apoptosis and necrosis: dependency on p38 mitogen-activated protein kinase" ppsx
... detection analyses indicated that
apoptosis accounted for only a portion of chondrocyte death,
whereas the other chondrocytes died by necrosis. Both
chondrocyte apoptosis and necrosis depended on ... finding is
Figure 3
Chondrocyte death consists of apoptosis and necrosisChondrocyte death consists of apoptosis and necrosis. (a) Morpho-
logic analysis of chondrocyte ap...
Báo cáo y học: "CD95-induced osteoarthritic chondrocyte apoptosis and necrosis: dependency on p38 mitogen-activated protein kinase" pps
... specifically
in the grey matter, suggesting that neuronal injury is among the
key factors in diffuse NPSLE. This hypothesis is supported by
increased levels of neuronal and astrocytic degradation prod-
ucts ... years); neuropsychiatric symptoms had been
diagnosed one month to 18 years (mean 5 years) before scan-
ning. At the time of the study, no active neuropsychiatric symp-
toms or any co...
Báo cáo Y học: Effects of ATP depletion and phosphate analogues on P-glycoprotein conformation in live cells docx
... suppression of
MM12.10 labeling after UIC2 binding) may be intrinsic to
the normal catalytic cycle, or, alternatively, the CsA-type
drugs may induce a special conformation adopted by Pgp
only in ... MM12.10 and UIC2 were
prepared as described previously [26,27].
Flow cytometric assays
Nearly confluent monolayers of cells were harvested by
2–3 min trypsin treatment [0.05% trypsin and 0.02%...
Báo cáo y học: "Antibodies to citrullinated proteins and differences in clinical progression of rheumatoid arthritis" ppsx
... in morning stiffness, type, location and
distribution of early symptoms, patients' rated disease activity
and C-reactive protein at inclusion between RA patients with
and without anti-CCP ... humoral response. Intriguingly,
this antibody response may occur years before any clinical
symptoms, as shown by the presence of anti-CCP antibodies
several years before the clinical onset o...
Báo cáo y học: "The relationship between cancer and rheumatoid arthritis: still a large research agenda" ppsx
... Anti-TNF antibody therapy in rheumatoid arthritis
and the risk of serious infections and malignancies: system-
atic review and meta-analysis of rare harmful effects in ran-
domized controlled trials. ... Chakravarty EF, Genovese MC: Associations between rheuma-
toid arthritis and malignancy. Rheum Dis Clin North Am 2004,
30:271-284, vi.
3. Bongartz T, Sutton AJ, Sweeting MJ, Buchan I,...
Báo cáo y học: "Impact of drug classes and treatment availability on the rate of antiretroviral treatment change in the TREAT Asia HIV Observational Database (TAHOD" pdf
... Yuliana, Faculty of Medicine Udayana University & Sanglah
Hospital, Bali, Indonesia;
S Oka* and M Honda, International Medical Centre of Japan, Tokyo, Japan;
JY Choi* and SH Han, Division ... Hospital
and AIDS Prevention and Research Centre, National Yang-Ming University,
Taipei, Taiwan;
PL Lim*, CC Lee and LC Koh, Tan Tock Seng Hospital, Singapore;
P Phanuphak* †, and M Kho...
Báo cáo y học: " Cholangiocarcinoma presenting as hemobilia and recurrent iron-deficiency anemia: a case report" ppsx
... Sayer JM, Long RG: A perspective on iron deficiency anaemia. Gut 1993,
34:1297-1299.
3. McIntyre AS, Long RG: Prospective survey of investigations in
outpatients referred with iron deficiency ... hepatectomy was subsequently performed with curative intent, and our patient has now fully
recovered.
Conclusion: This is a rare example of hemobilia and chronic iron-deficiency anemia in as...
Báo cáo y học: "4-Hydroxynonenal induces apoptosis in human osteoarthritic chondrocytes: the protective role of glutathione-S-transferase" doc
... regulation of
cyclooxygenase-2 and inducible nitric oxide synthase by 4-
hydroxynonenal in human osteoarthritic chondrocytes
through ATF-2/CREB-1 transactivation and concomitant inhi-
bition of ... quality stem from the
failure of chondrocytes to maintain a balance between protein
synthesis and degradation. Chondrocytes are the only cell
type found in mature cartilage, and their d...
Báo cáo y học: "ragmentation of Golgi complex and Golgi autoantigens during apoptosis and necrosis" ppt
... of
nuclear proteins in apoptosis and necrosis revealed by
autoantibody probes. Cell Death Differ 1998, 5:183-190.
21. Utz PJ, Anderson P: Posttranslational protein modifications,
apoptosis, and the bypass ... cells, prolonged
necrosis (primary or secondary), T-cell cytotoxicity asso-
ciated with chronic infection, or even antigen mutation
or overexpression. It would be important not...
Báo cáo y học: " Impairment of chondrocyte biosynthetic activity by exposure to 3-tesla high-field magnetic resonance imaging is temporar" pptx
... high-energy EMF may to some extent compro-
mise the biosynthetic activity and/ or function of articular
chondrocytes.
Although it is known that mechanical stress contributes to the
induction of chondrocyte ... impairment.
Conclusion
A high-energy EMF potentially impairs the biosynthetic activity
of articular chondrocytes; this effect is temporary, as shown
under the in vitro conditions emp...