Báo cáo y học: "Fibroblast activation protein alpha is expressed by chondrocytes following a pro-inflammatory stimulus and is elevated in osteoarthriti" docx

... human FAP α were: 5'-ATC- TATGACCTTAGCAATGGAGAATTTGT-3' and 5'-GTTTT- GATAGACATATGCTAATTTACTCCCAAC-3'. The primers used for bovine FAP α were 5'-ACCATGAAAAGTGTGAAT- GCTTCA-3' ... FAPα is expressed in many pathologies. FAPα is a type II transmembrane serine proteinase with a cyto- plasmic tail that contains six amino acids followed by a 20 amin...

Ngày tải lên: 09/08/2014, 07:20

... arthritis (RA) is a chronic inflammatory disease of unknown aetiology and is characterised by hyperplasia and chronic inflammation of the synovial membranes that invade deeply into the articular cartilage ... prod- uct was generated with 5'-CTGAAGGTGATGAAGCAGCC- 3' and 5'-AGTCCAAGAGAATGGCCGAG-3'. The MMP-13 PCR product was generated with 5'-CTATGGTCCAGGA...

Ngày tải lên: 09/08/2014, 08:23

... pathologies of RA and OA differ, it is clear that in both of these diseases pro-inflam- matory cytokines are present, resulting in an inflammatory state as well as cartilage degradation [14]. As further ... of pro-inflammatory cytokines in RA, anti-tumor necrosis factor-α (anti-TNF-α) and anti-inter- leukin 1 (anti-IL-1) therapies can reduce inflammation and retard the progres...

Ngày tải lên: 09/08/2014, 01:23

... RA. Indroduction Human rheumatoid arthritis (RA) is a chronic systemic disor- der of unknown aetiology, characterized by intimal lining layer hyperplasia, infiltration of the sublining area by macrophages, T and ... IL-6 and TNF-α are upregulated in RA as well as in AIA [20]. In sera, IL-6 was ele- vated in the acute phase (day 3) of AIA in comparison to non- arthritic,...

Ngày tải lên: 09/08/2014, 07:20

... (21159) Homsa;CYCG1 Homsa;CYCG2 Arath;CYCD4;1 Arath;CYCD2;1 Homsa;CYCJ Homsa;CYCE2 Arath;CYCB1;1 Arath;CYCB3;1 Thaps (36441) Phatr;CYCP6 Phatr;CYCP4 Phatr;CYCP1 Phatr;CYCP5 Phatr;CYCP3 Phatr;CYCP2 Phatr;CYCH1 Phatr;CYCL1 Phatr;CYCD1 Phatr;CYCA/B;1 Arath;SDS Phatr;CYC-like Thap ... Yamaguchi M, Fabian T, Sauter M, Bhalerao RP, Schrader J, Sandberg G, Umeda M, Uchimiya H: Activation of CDK-a...

Ngày tải lên: 09/08/2014, 20:21

... of maternal, patern al and dual AIDS orphans in each country at year 2020 following varying sc enarios of ART uptake. Mater- nal and paternal AIDS orphans were defined as children under the age ... of AI DS orphans incurred in Scenario 1 (Universal ART uptake) and Scenario 2 (Sustaining current rate of ART access) in 10 Sub-Saharan African countries by year 2020. Anema et al....

Ngày tải lên: 10/08/2014, 05:22

... were tested by one way analysis of variance (ANOVA). Mono- filament data were deemed to be ordinal and statistical analysis was performed using the Jonckheere-Terpstra (J- T) test, a non-parametric test ... peripheral neu- ropathy or impaired nerve responses, cancer therapy (current or in the past five years), myocardial infarction, angioplasty or bypass graft, rheumatoid arthritis, a...

Ngày tải lên: 10/08/2014, 21:23

... upon local pal- pation.TheresultsofLachman-Noulis,Apley ,and McMurray tests were negative, and X-rays showed no bony abnormalities. Initially, our predominant diagnosis was medial meniscal cyst. * ... Krinas 2 , Dimitris Kipriadis 2 , Apostolos Ilias 2 , Andreas Giannakopoulos 2 and Stephanos Kalos 2 Abstract Introduction: Large ganglionic cystic formations arising from the infrapatellar...

Ngày tải lên: 10/08/2014, 23:22

... improvement in his renal function. He is being maintained on hemodia- lysis after six months following his initial presentation. He is currently awaiting kidney transplantation. Discussion This case ... literature that have been associated with a high mortality and morbidity, and a very high rate of renal failure resulting in hemodialysis. Co-existence of membranous nephropa...

Ngày tải lên: 11/08/2014, 03:21

... formation in anti-GBM disease, increasing antigen synthesis by injured podocytes and facilitated by the capping and shedding of antigen-antibody complexes into the sube- pithelial space. Alternatively, ... design, acquisition, analysis and interpretation of data. NN and AT were involved in drafting the manuscript or revising it critically for important intellectual content. Al...

Ngày tải lên: 11/08/2014, 07:20