Báo cáo y học: "PTPN22 polymorphism and anti-cyclic citrullinated peptide antibodies in combination strongly predicts future onset of rheumatoid arthritis and has a specificity of 100% for the disease" ppsx

... polymorphism and anti-cyclic citrullinated peptide antibodies in combination strongly predicts future onset of rheumatoid arthritis and has a specificity of 100% for the disease Martin Johansson 1 , ... combination of anti-CCP antibodies and carriage of the PTPN22 1858T vari- ant gave a very high OR compared with not having any of...

Ngày tải lên: 09/08/2014, 07:20

Ngày tải lên: 09/08/2014, 10:20

... Inoue E, Toyama Y, Hara M, Yamanaka H, Tomatsu T, Momohara S, Kamatani N: Failure to confirm associ- ation between PDCD1 polymorphisms and rheumatoid arthri- tis in a Japanese population. J Hum Genet ... associated with rheumatoid arthritis in the European Caucasian population: a family-based study. Arthritis Res Ther 2007, 9:R63. 2. Friedlander M, Brooks PC, Shaffer RW,...

Ngày tải lên: 09/08/2014, 10:21

... nomenclature for these microdomains is highly variable and unstandardized. Caveolae are generally defined by both morphological and biochemical criteria (particu- larly their invaginated flask-like shape and ... FceRI are internalized relatively rapidly through coated pits, in contrast to LAT, the authors propose that the more stable LAT-containing domains are important in susta...

Ngày tải lên: 31/03/2014, 21:21

... results. Methods: The HADS was administered to 521 participants (275 controls and 246 inpatients and outpatients of the Internal Medicine and Surgical Departments in 'Attikon' General Hospital in Athens). ... drafted the manu- script, AD participated in data collection and drafted the manuscript, CK participated in data collection and processing, CC parti...

Ngày tải lên: 08/08/2014, 23:20

... following intravenous inoculation of bacteria and continued until day 10. Positive values indicate amelioration of arthritis and negative values indicate increased severity of arthritis between days ... rate * –0.8 –0.4 0 0.4 dants that participate in the destruction of invading microor- ganisms [14]. PBN scavenges radicals and probably decreases phagocyte bactericidal c...

Ngày tải lên: 09/08/2014, 03:24

... confronts the generally inevitable pain in the joints that limits mobility as a result of osteoarthritis. Osteoarthritis is characterized by articular cartilage damage and the resultant repair response including ... Smad (C-Smad; also known as Smad 4) and inhibitory Smads (Smads 6 and 7). The Commentary Aging, osteoarthritis and transforming growth factor- ββ signaling...

Ngày tải lên: 09/08/2014, 07:20

... the vWF parameter was performed using a Mini-Vidas auto- mated immunoassay system that uses ELFA (Enzyme- Linked Fluorescent Assay) technology. The Mini-Vidas system and immunoassa y kits were ... following THR and TKR surgery. This e vi- denceindicatesthatCD62Lmayplayaroleduringthe early rolling stages of the leukocyte adhesion cascade and provides further evidence that mon...

Ngày tải lên: 11/08/2014, 08:22

... report and any accompanying images. A copy of the written consent is available for review by the Editor -in- Chief of this journal. Competing interests The author declares that they have no competing ... unclear, although many hypotheses have been made to explain the manifestations of this syndrome. It has been suggested that pulmonary artery aneurysms may arise from a...

Ngày tải lên: 11/08/2014, 12:20

... leaving ICV containing brain and CSF for that slice. Next the estimate of CSF - brain boundary was examined and corrected visually by hand as necessary, and C SF in that slice was removed, leaving ... intracranial volume has been a topic of interest since the advent of the capacity to image the brain. The earliest imaging strateg y, pneumoencephalography, was i...

Ngày tải lên: 11/08/2014, 16:22