Báo cáo y học: "PTPN22 polymorphism and anti-cyclic citrullinated peptide antibodies in combination strongly predicts future onset of rheumatoid arthritis and has a specificity of 100% for the disease" ppsx
Báo cáo y học: "PTPN22 polymorphism and anti-cyclic citrullinated peptide antibodies in combination strongly predicts future onset of rheumatoid arthritis and has a specificity of 100% for the disease" ppsx
... polymorphism and anti-cyclic citrullinated peptide antibodies in combination strongly predicts future onset of rheumatoid arthritis and has a specificity of 100% for the diseaseMartin Johansson1, ... combination of anti-CCP antibodies and carriage of the PTPN22 1858T vari-ant gave a very high OR compared with not having any of them. As none of the controls had this combination, the ORwas ... for developing RA than the combination of the T variant and HLA-SE (OR = 7.85). The PTPN22 1858T variant was associatedwith future development of RA. There was an associationbetween the T variant and...
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Báo cáo y học: "ITGAV polymorphism and disease susceptibility in a Japanese rheumatoid arthritis population" ppsx
... Inoue E, Toyama Y, Hara M, Yamanaka H,Tomatsu T, Momohara S, Kamatani N: Failure to confirm associ-ation between PDCD1 polymorphisms and rheumatoid arthri-tis in a Japanese population. J Hum Genet ... associated with rheumatoid arthritis in the European Caucasian population: a family-based study. Arthritis Res Ther 2007, 9:R63.2. Friedlander M, Brooks PC, Shaffer RW, Kincaid CM, Varner JA,Cheresh ... S, Alibert O, Quillet P,et al.: Dense genome-wide linkage analysis of rheumatoid arthritis, including covariates. Arthritis Rheum 2004, 50:2757-2765.5. Iwamoto T, Ikari K, Inoue E, Toyama Y, ...
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Báo cáo Y học: Lipid rafts and little caves Compartmentalized signalling in membrane microdomains pot
... nomenclature for these microdomains is highlyvariable and unstandardized. Caveolae are generally definedby both morphological and biochemical criteria (particu-larly their invaginated flask-like shape and ... FceRIare internalized relatively rapidly through coated pits, in contrast to LAT, the authors propose that the more stableLAT-containing domains are important in sustaining and amplifying signalling ... rafts can dramatically affect the signalling capability of antigen-bound BCR.Lipid rafts also appear to be involved in regulation of signalling by a n umber of cytokine receptors, including the interleukin-2...
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Báo cáo y học: "Hospital Anxiety and Depression Scale (HADS): validation in a Greek general hospital sample" pdf
... results.Methods: The HADS was administered to 521 participants (275 controls and 246 inpatients and outpatients of the Internal Medicine and Surgical Departments in 'Attikon' General Hospital in Athens). ... drafted the manu-script, AD participated in data collection and drafted the manuscript, CK participated in data collection and processing, CC participated in data collection and revised the manuscript, ... participated in data collec-tion and processing, KP participated in data collection and processing, and LL was co-designer of the study and gave final approval to the published version. All authorsread...
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Báo cáo y học: "Combined antibiotic and free radical trap treatment is effective at combating Staphylococcus-aureus-induced septic arthritis" ppt
... followingintravenous inoculation of bacteria and continued until day 10. Positivevalues indicate amelioration of arthritis and negative values indicateincreased severity of arthritis between days ... rate*–0.8–0.400.4dants that participate in the destruction of invading microor-ganisms [14]. PBN scavenges radicals and probablydecreases phagocyte bactericidal capacity, thereby increas-ing the bacterial ... developed as a means of trapping and detecting free radical intermediates[7]. PBN and related nitrones have a variety of anti-inflam-matory and antioxidant properties. Therefore we consid-ered whether...
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Báo cáo y học: " Aging, osteoarthritis and transforming growth factor-β signaling in cartilage" pps
... confronts the generally inevitable pain in the joints that limits mobility as a result of osteoarthritis. Osteoarthritis is characterized byarticular cartilage damage and the resultant repair responseincluding ... Smad (C-Smad; also known asSmad 4) and inhibitory Smads (Smads 6 and 7). The CommentaryAging, osteoarthritis and transforming growth factor-ββsignaling in cartilage A Hari ReddiLawrence J Ellison ... http:/ /arthritis- research.com/content/8/1/101AbstractOsteoarthritis is a common malady of the musculoskeletal systemaffecting the articular cartilage. The increased frequency of osteo- arthritis with aging indicates the complex...
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Báo cáo y học: "Total hip and knee replacement surgery results in changes in leukocyte and endothelial markers." pptx
... the vWF parameter was performed using a Mini-Vidas auto-mated immunoassay system that uses ELFA (Enzyme-Linked Fluorescent Assay) technology. The Mini-Vidassystem and immunoassa y kits were ... following THR and TKR surgery. This e vi-denceindicatesthatCD62Lmayplayaroleduringtheearly rolling stages of the leukocyte adhesion cascade and provides further evidence that monocytes follow a similar ... VenflonTM,Sweden) was inserted into the arm at the ante-cubitalfossa. A venous blood sample was then collected preo-peratively, which stood as a ba seline measurement for that particular patient. In theatre,...
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Báo cáo y học: "Massive hemoptysis and deep venous thrombosis presenting in a woman with Hughes-Stovin syndrome: a case report" ppsx
... report and any accompanyingimages. A copy of the written consent is available for review by the Editor -in- Chief of this journal.Competing interests The author declares that they have no competing ... unclear, although manyhypotheses have been made to explain the manifestations of this syndrome. It has been suggested that pulmonaryartery aneurysms may arise from a degenerative defect in the ... [5,9,11,17]. The advan-tages of embolization are that it is less invasive and has the ability to treat multiple and bilateral aneurysms. Cor-ticosteroids, alone or in combination with cytotoxicdrugs,...
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Báo cáo y học: " Brain size and brain/intracranial volume ratio in major mental illness" doc
... leaving ICV containing brain and CSF for thatslice. Next the estimate of CSF - brain boundary wasexamined and corrected visually by hand as necessary, and C SF in that slice was removed, leaving ... intracranialvolume has been a topic of interest since the advent of the capacity to image the brain. The earliest imaging strateg y, pneumoencephalography, was introduced by WalterDandy, chief resident for ... categori-cal approach [30]. There is also an intrinsic confound in the d iagnosis of SAD insofar as that a patients initiallydiagnosed as SZ may sometime later (perhaps years)develop and affective...
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