Báo cáo y học: "Analysis of Fcγ receptor haplotypes in rheumatoid arthritis: FCGR3A remains a major susceptibility gene at this locus, with an additional contribution from FCGR3B" ppsx

... article Analysis of Fcγ receptor haplotypes in rheumatoid arthritis: FCGR 3A remains a major susceptibility gene at this locus, with an additional contribution from FCGR3B Ann W Morgan 1,2 , ... undertook all database searches, oversaw all aspects of the laboratory work, analyzed the data and prepared the manuscript. JHB gave additional statistic...

Ngày tải lên: 09/08/2014, 07:20

... Marciniuk—Division of Respiratory Medicine, Department of Medicine, University of Saskatchewan, Royal University Hospital, Saskatoon, Saskatchewan; D. D. Marciniuk—Lung Association of Saskatchewan COPD Professorship; ... deaths, and 470,000 hospitalizations each year. 1 Previously characterized as a disease of air- way smooth muscle, asthma is currently defined by the National He...

Ngày tải lên: 08/08/2014, 20:23

... 34:1125-1132. 24. Takayanagi H, Iizuka H, Juji T, Nakagawa T, Yamamoto A, Miyazaki T, Koshihara Y, Oda H, Nakamura K, Tanaka S: Involvement of receptor activator of nuclear factor kappaB ligand/osteoclast differentiation ... alterations of bone turnover, as typically seen in juxta-articular and periarticular damage of inflamed joints in RA. TNF is a proinflammatory cytokine...

Ngày tải lên: 09/08/2014, 07:20

... first year of data as baseline and the second year as comparator. Finally, an additional and similar analysis was performed for hospitals that had partici- pated in the MERIT study. A P value of ... in- hospital CAs in a number of single-centre before-and-after studies [5-9]. A ANZ = Australia and New Zealand; ANZICS = Australian and New Zealand Intensive Care Society; AN...

Ngày tải lên: 25/10/2012, 10:35

... polyendocrinopathy, enteropathy, X- linked syndrome) [4] or scurfy mice [5] or by means of depletion with anti-CD25 monoclonal antibodies in animal models, favours the initiation of a variety of autoimmune diseases ... Taams LS, Patel A, Varsani H, Klein M, de Jager W, Pugayung G, Giannoni F, Rijkers G, et al.: CD4 + CD25 bright regulatory T cells actively regulate inflamma- tion...

Ngày tải lên: 09/08/2014, 06:23

... history of gradually worsening numbness and paresthesia on the palmar aspect of the left thumb and thenar eminence. Clinical examination reveals a hypoaesthesia in the median nerve area of the ... paraosteal localizations [9]. Lipomas of more than 5 cm diameter (Giant lipoma) are infrequent in the upper limb [10]. In this anatomic location, masses are generally symptomatic...

Ngày tải lên: 10/08/2014, 10:20

... instructions. Statistical analysis Statistical analysis was performed using the Statview soft- ware (Abacus Concept Inc., Cary, NC, USA). Means were Table 1 Patient characteristics Characteristic All RA patients ... production usually induced by TNF-α. This profile suggests that these patients may have a high level of innate neutralizing TNF-α activity and/or no circulating active TNF-α...

Ngày tải lên: 09/08/2014, 06:22

... oedema scored on magnetic resonance scans of the dominant carpus at presentation pre- dicts radiographic joint damage at the hands and feet six years later in patients with rheumatoid arthritis. Arthritis Rheum ... from a patient with a 1 year history of RA is shown in Figure 1. Finally, animal studies are emerging to clarify the role of the bone marrow as a site...

Ngày tải lên: 09/08/2014, 08:23

... fellow phagocytic cells of the monocyte/ macrophage lineage. Their rapid secretion of many factors that are also released by macrophages, lymphocytes and fibroblasts indicates that they can play similar ... chronic inflammatory diseases, such as RA, indicates that these cells may play an important role in chronic inflammation. It is increasingly apparent neutrophils exhibit many of...

Ngày tải lên: 09/08/2014, 10:20

... SLE diagnosis, the index case, was included in the statistical analysis. The mean age at diagnosis of the patients was 40 years (range 10–83) and the mean disease duration was 16 years (range ... http://arthritis-research.com/content/6/6/R557 R561 Competing interests None declared. Author contributions AJ was responsible for data analysis and interpretation and wrote the report. AAB con...

Ngày tải lên: 09/08/2014, 01:24