Báo cáo y học: "The impact of HLA-DRB1 genes on extra-articular disease manifestations in rheumatoid arthritis" doc

... hydroxylation [28]. Hydroxylation occurs at the β-carbon of the asparagine residue, consequently (by way of steric hindrance) preventing the interaction of the HIF-α C-TAD with the cysteine/histidine-rich ... intracellular domain of the Notch receptor (involved in the maintenance of cells in an undifferentiated state), both of which notably contain ankyrin repeat motifs contai...

Ngày tải lên: 09/08/2014, 01:22

... hydroxylation [28]. Hydroxylation occurs at the β-carbon of the asparagine residue, consequently (by way of steric hindrance) preventing the interaction of the HIF-α C-TAD with the cysteine/histidine-rich ... intracellular domain of the Notch receptor (involved in the maintenance of cells in an undifferentiated state), both of which notably contain ankyrin repeat motifs contai...

Ngày tải lên: 09/08/2014, 13:22

... 2 Frequency distribution of physical component summary scoresFrequency distribution of physical component summary scores. Frequency distribution of baseline physical component summary scores ... the type of arthritis [1]. PsA typically includes psoriatic skin lesions and has a sim- ANCOVA = analysis of covariance; AS = ankylosing spondylitis; ASSERT = Ankylosing Spondylitis Study...

Ngày tải lên: 09/08/2014, 10:21

... of Rheumatology (ACR) in 1987 consisting of clinical symptoms and radiologi- cal findings, whereas the only laboratory test included is the serum rheumatoid factor (RF) determination [2]. The ACR ... receiving operating characteris- tic (ROC) curve was constructed by plotting sensitivity against one minus specificity (1 – specificity), varying the cutoffs [9,26]. Diagnostic values of...

Ngày tải lên: 09/08/2014, 08:22

... infection control committees many years before the initiation of the NARP. Even in these selected centres already apply- ing local antibiotic restriction policies the utilisation of many of ... forms of ciprof- loxacin and levofloxacin were not restricted for the first three days of therapy by NARP, the consumption of these quinolones was unsurprisingly high. Besides that t...

Ngày tải lên: 25/10/2012, 11:00

... 0.19. ExRA, extra-articular rheumatoid arthritis; SE, shared epitope. Figure 1 Variation in frequency of HLA-DRB1* 0401 by disease phenotype in RAVariation in frequency of HLA-DRB1* 0401 by disease ... HLA-DRB1* 04 alleles. In a Figure 2 ExRA manifestations among those carrying carrying HLA-DRB1* 04 shared epitope allelesExRA manifestations among those carrying ca...

Ngày tải lên: 09/08/2014, 07:20

... physical findings of lipodystrophy as determined by physician examina- tion. Additional study will be needed to determine the longitudinal effects of lipodystrophy on healthcare utili- zation ... half of subjects with lipodystrophy in this cohort had reported lipodystrophy of at least 28 months duration at the time of study, and subjects with a longer duration of lipodystrophy...

Ngày tải lên: 10/08/2014, 05:21

... steady increase in the number of calls to the hotline since its inception, with over 300 calls per month in May 2010. During the two months of the st udy, 511 calls were received by the National ... investigations, referring or admission of patients. Conclusions: The information provided by the National HIV HCW Hotline on patient-specific requests has a direct impact on the ma...

Ngày tải lên: 10/08/2014, 05:21

... little influence on adverse outcomes which may instead reflect the impact of the underlying disease and/or global manifestations of treatment: Two meta-analyses confining analysis to neuropsychological outcomes ... toxicity. J Consult Clin Psychol 1992, 60(3):477-480. 46. Usner D, FitzGerald G: Analytic implications of changing neuropsychological test versions during a longitudi...

Ngày tải lên: 10/08/2014, 21:23

... DP, Condon JR, Anderson IP, Li SQ, Halpin S, Cunningham J, Guthridge SL: Long-term trends in indigenous deaths from chronic diseases in the Northern Territory: a foot on the brake, a foot on the accelerator. ... separations recorded by females. Discussion Thefindingsofthisstudyindicatethereisvariation between total hospital separations for diabetes related foot disease across socioe...

Ngày tải lên: 10/08/2014, 21:24