Báo cáo y học: "Reduced transforming growth factor-beta signaling in cartilage of old mice: role in impaired repair capacity" ppsx
Báo cáo y học: "Reduced transforming growth factor-beta signaling in cartilage of old mice: role in impaired repair capacity" ppsx
... TGF-beta signaling proteins in cartilageEffect of IL-1 on expression of TGF-beta signaling proteins in cartilage. Knee joints of (a) young (5 months old) and (b) old (2 years old) mice were injected ... transforming growth factor (TGF)-beta signaling molecules in cartilageStaining of various transforming growth factor (TGF)-beta signaling molecules in c...
Ngày tải lên: 09/08/2014, 07:20
Báo cáo y học: "Human articular chondrocytes express 15-lipoxygenase-1 and -2: potential role in osteoarthritis" pdf
... Brogley MA, Sun Y, Cheung HS: Molecular mecha- nism of the induction of metalloproteinases 1 and 3 in human fibroblasts by basic calcium phosphate crystals. Role of cal- cium-dependent protein kinase ... metab- olites may have therapeutic promise in OA by preventing the production of cartilage- degrading enzymes. Competing interests The authors declare that they have no compet...
Ngày tải lên: 09/08/2014, 14:20
Báo cáo y học: "Clinical and neuropathological study about the neurotization of the suprascapular nerve in obstetric brachial plexus lesions" potx
... pres- ence of minifascicles is an indicator of the lower quality of the nerve involved in the neurorrhaphy, potentially com- promising the clinical results. Statistical evaluation The clinical values ... an indication of the thickness of the myelin in the axon. - The G-ratio (axon diameter (μm)/total nerve fiber diameter (μm)) is often used in the literature indicat- ing the d...
Ngày tải lên: 10/08/2014, 10:20
Báo cáo y học: "Reduced IgG anti-small nuclear ribonucleoprotein autoantibody production in systemic lupus erythematosus patients with positive IgM anti-cytomegalovirus antibodies" pdf
... Systemic Lupus Erythematosus Disease Activity Index and the Systemic Lupus International Collaborating Clin- ics/American Collage of Rheumatology Damage Indexes at the beginning of the study ... of Rheumatology and Clinical Immunology, Department of Medicine, University of Florida, P.O. Box 100221, Gainesville, FL 32610-0221, USA 3 Department of Pathology, Immunology, and Laborat...
Ngày tải lên: 09/08/2014, 01:22
Báo cáo y học: "Reduced number and impaired function of circulating progenitor cells in patients with systemic lupus erythematosus" pot
... carboxy-terminal half of the proteolytic domain. Caspase 8L binds to the Fas-asso- ciating protein with death domain (FADD) and blocks the bind- ing of caspase 8 to FADD by competiive inhibition ... not intrinsically impaired in their functionality, but are impaired due to extrinsic factors. Culturing of CPCs in defined conditions for 14 days has resulted in near to normal fun...
Ngày tải lên: 09/08/2014, 10:20
Báo cáo y học: "Reduced proportions of natural killer T cells are present in the relatives of lupus patients and are associated with autoimmunity" ppt
... regions defined by the levels of staining with anti-CD27 and anti-CD38, as determined by staining with a relevant isotype control. Using this combination of stains, B cells can be divided into naïve ... Department of Medicine, Faculty of Medicine, University of Manitoba, Sherbrook Street, Winnipeg, Manitoba, R3A 1M4, Canada 12 Division of Rheumatology, Department of Medicine,...
Ngày tải lên: 09/08/2014, 13:21
Báo cáo y học: "Reduced rates of primary joint replacement for osteoarthritis in Italian and Greek migrants to Australia: the Melbourne Collaborative Cohort Study" doc
... follow-up of the MCCS, physical functioning was assessed by asking five questions: Did health problems limit you in your everyday physical activity? Did pain interfere with your normal work? Has your ... people in Italy have a low rate of joint replacements [20]. Overseas migration has played a key role in shaping Australia as one of the most culturally diverse nations in the...
Ngày tải lên: 09/08/2014, 14:21
Báo cáo y học: " Reduced Fas ligand-expressing splenic CD5+ B lymphocytes in severe collagen-induced arthritis" pps
... cells, particularly Th17 cells, which produce the proinflammatory cytokine interleukin (IL)-17, play an important role in mediating arthritis [6-9]. The role of Th17 cells in human RA is less ... level of control of Th cell activity involves the induction of Th cell death (apoptosis), which can be mediated through intrinsic or extrinsic pathways. The best studied extrinsic pat...
Ngày tải lên: 09/08/2014, 14:22
Báo cáo y học: " Reduced levels of two modifiers of epigenetic gene silencing" ppsx
... probability of a second mutation in the coding region of this interval is extremely low (P = 0.0006 [17]). Based on these findings, in combination with the fact that homozygous mutant embryos [9] ... recently identified as playing a central role in lipid metabolism and metabolic syndrome [20]. Ingenuity Pathway Analysis of dysregulated genes revealed that the two top canonical p...
Ngày tải lên: 09/08/2014, 22:23
Báo cáo y học: "Reduced levels of two modifiers of epigenetic gene silencing, Dnmt3a and Trim28, cause increased phenotypic nois" pdf
... metabolic syndrome [20]. Ingenuity Pathway Analysis of dysregulated genes revealed that the two top canonical pathways were ‘LPS/ IL-1 mediated inhibition of RXR function’ and ‘ Glycine, serine and ... components of random variability in quantitative traits. Reduction of genetic variability, by using inbred strains, and reduction of environmental variability, by standardized husba...
Ngày tải lên: 09/08/2014, 22:23