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Báo cáo y học: "Raloxifene reduces urokinase-type plasminogen activator-dependent proliferation of synoviocytes from patients with rheumatoid arthritis" docx

Báo cáo y học:

Báo cáo y học: "Raloxifene reduces urokinase-type plasminogen activator-dependent proliferation of synoviocytes from patients with rheumatoid arthritis" docx

... healthy (H) and rheumatoid arthritis (RA) synoviocytesUrokinase-type plasminogen activator u-PA/u-PA receptor-dependent proliferation in healthy (H) and rheumatoid arthritis (RA) synoviocytes. Synoviocytes ... activity in healthy (H) and rheumatoid arthritis (RA) synoviocytes treated with Raloxifene (RAL )Urokinase-type plasminogen activator (u-PA) activity in healthy (H) and rheumatoid arthritis (RA) synoviocytes ... http://arthritis-research.com/content/7/6/R1244R1244Vol 7 No 6Research articleRaloxifene reduces urokinase-type plasminogen activator-dependent proliferation of synoviocytes from patients with rheumatoid arthritisS Guiducci1, A Del Rosso1,...
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Báo cáo y học: "DAS28: a useful instrument to monitor infliximab treatment in patients with rheumatoid arthritis" pps

... states of low and highdisease activity, in a sample of 202 patients [6]. A recentstudy used a different, opinion-based, approach, with expertrating (n = 35) of a sample of clinical profiles ... disease activity, moderatedisease activity and high disease activity [7]. Interestingly, thecut-off criteria for the DAS28 that were found in this waywere only slightly different from the established ... low disease activityto study the validity of the Disease Activity Score and theDAS28. In a study performed in Italy in the late 1990s, it wasfound that the Disease Activity Score was the best...
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Báo cáo y học: "A2B adenosine receptor activity is reduced in neutrophils from patients with systemic sclerosis" ppt

... Martini21Department of Internal Medicine, Division of Rheumatology, University of Pisa, Pisa, Italy2Departments of Psychiatry, Neurobiology, Pharmacology and Biotechnology, University of Pisa, Pisa, ItalyCorresponding ... (2-p-[2-car-bowyethyl]pheylethylamino)-5'N-ethylcarboxamidoadenosine; CPA = cyclopentyladenosine; Kd = affinity constant; NECA = 5'-N-ethylcarboxami-doadenosine; R-PIA = R-N6-phenylisopropyladenosine; ... stimulation of adenylyl cyclase activity in control (empty circles) and systemic sclerosis (SSc; filled cir-cles) neutrophil membranesA2B adenosine receptor (AR)-mediated stimulation of adenylyl cyclase...
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Báo cáo y học: " Autonomic Dysfunction Presenting as Postural Orthostatic Tachycardia Syndrome in Patients with Multiple Sclerosis"

... inflammatory de-myelinating disease of the central nervous system (CNS) that is a leading cause of disability in young adults. Autonomic dysfunction is commonly seen in patients with MS (1-5). In patients ... amount of activity per-formed. Many patients complain of feeling exhausted on waking, even if they have slept soundly. Fatigue can also occur during the day but may be only par-tially relieved ... management of POTS in patients of MS was similar to that in patients without a history of MS. In our small group of patients, six patients showed a good response to a combination of medications...
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Báo cáo y học: "A case study evaluating the use of clozapine in depression with psychotic feature" docx

... had failed.Efficacy of clozapine was satisfactory in 55–72% of patients with organic psychosis, mania, psychotic depression or Parkinson's disease.Majority of patients had schizophrenia ... Br J Psychiatry1993, 163:822-4.9. Hrdlicka M: Combination of clozapine and maprotiline inrefractory psychotic depression. Eur Psychiatry 2002, 17(8):484.Annals of General Psychiatry 2006, ... Sheexperienced difficulty waking up and problems with hershort-term memory.Annals of General Psychiatry 2006, 5:20 http://www.annals-general-psychiatry.com/content/5/1/20Page 2 of 6(page number...
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Báo cáo khoa học: "Taurolidine reduces the tumor stimulating cytokine interleukin-1beta in patients with resectable gastrointestinal cancer: a multicentre prospective randomized trial" doc

... every group included 60 patients. We alsoassessed other long-term values: probability of overall sur-vival and of being free of recurrence. Because of the objec-tive of the study patients with ... informed of the details of the study. Before induction of general anaes-thesia a single dose of antibiotic prophylaxis with cefuro-xim (1.5 g iv) and metronidazol (500 mg iv) was given. Aurinary ... bio-chemistry, ultrasound of the abdomen, and in suspicion of relapse, abdominal CT-scan. Pulmonary metastaseswere detected with thoracic X-ray or thoracic CT-scan.Results of a median follow-up of 50.0...
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Báo cáo y học: "Acute phase reactants add little to composite disease activity indices for rheumatoid arthritis: validation of a clinical activity score" potx

... M, Smolen JS:Benefit of very early referral and very early therapy with dis-ease-modifying anti-rheumatic drugs in patients with early rheumatoid arthritis. Rheumatology (Oxford) 2004, 43:906-914.10. ... patients into 10 ordered groups for each of thefour scores (from the group comprising the 10% of patients with the lowest activity to that consisting of the 10% with thehighest activity, by ... increase the feasibility of calculating thescore.In a cross-sectional analysis of a large number of patients, theCDAI not only had correlational validity compared with theSDAI, from which it was...
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Báo cáo y học: "Is there an association between anti-TNF monoclonal antibody therapy in rheumatoid arthritis and risk of malignancy and serious infection" ppt

... anCommentaryIs there an association between anti-TNF monoclonal antibodytherapy in rheumatoid arthritis and risk of malignancy andserious infection? Commentary on the meta-analysis byBongartz ... Watson K, Lunt M, Hyrich KL, British Society forRheumatology Biologics Register Control Centre Consortium,Silman AJ, Symmons DPM, on behalf of the British Society forRheumatology Biologics Register: ... bacterial intracellular infectionrates, in rheumatoid arthritis patients treated with anti-TNFααtherapy: Results from the British Society for RheumatologyBiologics Register (BSRBR). Arthritis...
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Báo cáo y học: "Catechol-O-methyltransferase gene haplotypes in Mexican and Spanish patients with fibromyalgia" docx

... autonomicdysfunction is frequent in patients with FM. Heart rate variabil-ity analyses have demonstrated signs of ongoing sympathetichyperactivity. This hyperactivity is accompanied by a bluntedCOMT ... properly cited.AbstractAutonomic dysfunction is frequent in patients with fibromyalgia(FM). Heart rate variability analyses have demonstrated signs of ongoing sympathetic hyperactivity. Catecholamines ... identify frequentCOMT gene haplotypes strongly associated with sensitivity toexperimental pain and induction of a more defective COMTenzyme. Healthy females with the 'high pain sensitivity...
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Báo cáo y học: "Apoptosis is not the major death mechanism induced by celecoxib on rheumatoid arthritis synovial fibroblasts" pps

... fibroblast-like synoviocytes of patients with rheumatoid arthritisFibroblasts were isolated from synovium obtained from patients who met the American College of Rheumatology cri-teria for ... The pannus is characterizedby a synovial hyperplasia that is mainly composed of fibroblast-like synoviocytes (FLSs) combined with a massive infiltration of lymphocytes and macrophages [3,4]. ... concentrations of celecoxib and subsequently ana-lyzed for cell activity using MTS assay. Cell activity of RA FLSswas clearly reduced by the addition of 40 μM celecoxib andcompletely abrogated...
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