Báo cáo y học: "Pro-inflammatory properties of stromal cell-derived factor-1 (CXCL12) in collagen-induced arthritis" pptx
Báo cáo y học: "Immunomodulatory properties of human adult and fetal multipotent mesenchymal stem " pptx
... regulators of
immunity display an extraordinary capacity to induce
T cell responses and secrete a variety of cytokines; the
differentiation status of DCs can influence whether its
target lymphocyte–often ... being involved in one study [71] but not in
another study [72]. This discrepancy may be due to the
subtle phenotypic variations induced in BMMSCs by the
many methods available...
Báo cáo y học: "Differential expression of the FAK family kinases in rheumatoid arthritis and osteoarthritis synovial tissues" doc
... activated, probably as a
result of inflammation in RA ST. Focal adhesion kinase (FAK)
and proline-rich tyrosine kinase (Pyk)2 are two members of a
family of nonreceptor protein tyrosine kinases that ... by a variety of extracellular stimuli [1]. FAK and Pyk2
associate with the cytoskeleton and with integrin-signaling
complexes by binding to Src kinase and paxillin [2-5]. FAK is
rapi...
Tài liệu Báo cáo Y học: Kinetic properties of bifunctional 6-phosphofructo-2-kinase/ fructose-2,6-bisphosphatase from spinach leaves pdf
... min. The supernatant was adjusted to 3%
poly(ethylene glycol) 4000 by adding 0.11 vol. of a 30%
poly(ethylene g lycol) solution in buffer A . After 5 min,
precipitated protein was removed by ... discrepancy, the
6PF2K activity of the recombinant enzyme is inhibited by
the s ame range of three-carbon phosphorylated intermedi-
ates as that of the enzyme from spinach leaves [8,10,11]....
Báo cáo Y học: Electrostatic properties of the structure of the docking and dimerization domain of protein kinase A IIa doc
... in Fig. 4, dimerization of RIIa D/D is main-
tained by strong hydrophobic interactions of side chains
that form the core of the protein at the dimer interface. The
formation of a clustering of ... by A-Kinase
Anchoring Proteins (AKAPs). The site of interaction with
AKAPs is the N-terminal docking and dimerization (D/D)
domain of the regulatory (R) subunit of PKA. While early...
Báo cáo Y học: Enzymic properties of recombinant BACE2 pdf
... bonds in the C-terminal subdomain, Cys233–
Cys433 and Cys292–Cys457, fasten the C-terminal peptide
to the main body of the catalytic unit (Fig. 6). Both disulfide
bonds as well as the C-terminal ... specificity of PB2-T1
and PB2-T2 toward intact protein substrates, some
commercially available proteins, which include human
serum albumin, cytochrome C, lysozyme, alcohol dehy-
drogenase, b-a...
Báo cáo y học: "Immunomodulatory properties of mesenchymal stem cells: a review based on an interdisciplinary meeting held at the Kennedy Institute" potx
... was to bring together workers in the fields of MSC
biology and AD in order to define areas of potential synergy
and interdisciplinary collaboration. As pointed out by the
director of the institute, ... of STAT5 Murine in vitro [76] (2006)
phosphorylation in lymphocytes
DC, dendritic cell; HGF, hepatocyte growth factor; IDO, indoleamine 2′,3′-dioxygenase; IL, interleukin; MLR,...
Báo cáo y học: "Ultrasound properties of articular cartilage in the tibio-femoral joint in knee osteoarthritis: relation to clinical assessment (International Cartilage Repair Society grade)" pptx
... Toshiya Sato, PhD, Professor of Biostatistics, Graduate School of
Medicine, Kyoto University, for advising on the statistical analysis.
References
1. Toyras J, Lyyra-Laitinen T, Niinimaki M, Lindgren ... of Medicine, Kyoto University, 54 Kawahara-Cho, Shogoin, Sakyo-Ku, Kyoto 606-8507, Japan
3
Department of Applied Medical Engineering Science, Graduate School of Medicine, Yamaguchi...
Báo cáo y học: "Different properties of ACPA and IgM-RF derived from a large dataset: further evidence of two distinct autoantibody systems" potx
... M, Papa N, Cinquini M, Magrini L, Tin-
cani A, Valesini G: Decrease of anti-cyclic citrullinated peptide
antibodies and rheumatoid factor following anti-TNFalpha
therapy (infliximab) in rheumatoid ... study, up to 25% of per-
sons more than 85 years old were IgM-RF-positive [10]. In a
similar study, ACPA positivity was observed in only 1 out of
300 healthy individuals over 75 year...
Báo cáo Y học: Defective translocation of a signal sequence mutant in a prlA4 suppressor strain of Escherichia coli doc
... change that results in bypassing a proofreading
mechanism of the Sec machinery [25].
The energy for precursor translocation is supplied by the
hydrolysis of ATP by SecA and by the proton-motive ... mutation in secY
reduced the pmf dependency of protein translocation [21].
Similarly, a single amino-acid substitution, replacing the
helix-breaking glycine at position )10 in the hydro...
Báo cáo Y học: The role of hydrophobic active-site residues in substrate specificity and acyl transfer activity of penicillin acylase pdf
... Tyr. These mutations may
in uence the shape and volume of the acyl binding pocket
and thereby alter the binding mode and affinity of the
enzyme for PAA and derivatives thereof, while maintaining
the ... phenylglycyl- and p-hydroxyphe-
nylglycyl-enzyme of bF24A, as indicated by, respectively, a
twofold and fourfold increased V
s
/V
h
ratiocomparedtothe
wild-type (Table 4). The V
s
/V
h
r...
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