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Báo cáo y học: "A functional variant of Fcγ receptor IIIA is associated with rheumatoid arthritis in individuals who are positive for anti-glucose-6-phosphate isomerase antibodies" doc

Báo cáo y học:

Báo cáo y học: "A functional variant of Fcγ receptor IIIA is associated with rheumatoid arthritis in individuals who are positive for anti-glucose-6-phosphate isomerase antibodies" doc

... online http:/ /arthritis- research.com/content/7/6/R1183R1183Vol 7 No 6Research articleA functional variant of Fcγ receptor IIIA is associated with rheumatoid arthritis in individuals who are ... antibody induced arthritis [2,3], suggesting that FcγRIII is indispensible in autoantibody dependent arthritis. In humans FcγRs are encoded by eight genes, and the genes encoding the lowaffinity FcγRs ... affinity of theFcγRs.Introduction Rheumatoid arthritis (RA) is a heterogeneous autoimmune dis-ease that is characterized by chronic inflammatory polyarthritis[1]. One of the characteristic...
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Báo cáo Y học: A functional role of the membrane-proximal extracellular domains of the signal transducer gp130 in heterodimerization with the leukemia inhibitory factor receptor pot

Báo cáo Y học: A functional role of the membrane-proximal extracellular domains of the signal transducer gp130 in heterodimerization with the leukemia inhibitory factor receptor pot

... be involved in thedimerization and activation of gp130 by formation of disulfide bonds [30]. The analysis of cysteine residues in gp130 led to the finding that the two N-terminal cysteines of D5 ... IL-4Rconsist of only a single cytokine binding module (CBM).The CBM is made up of two fibronectin type III-like(FNIII) domains containing some characteristic conservedmotifs in their primary structures. ... associates with tyrosine kinases of the Janus kinase (Jak) family. Upon ligand binding the associated Jaks become activated by transphosphorylationand phosphorylate tyrosine residues in the cytoplasmic...
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Báo cáo y học:

Báo cáo y học: "A Randomized Study of Epithelial Ovarian Cancer: Is Chemotherapy Useful after Complete Remission"

... Martin Donach, having completed his B.A. in Biochemistry at New York University, is presently in his final year of medical studies at the University of Padua and will pursue resident training in ... study examined 122 randomized patients in complete remission as judged by laparoscopy or laparotomy following first-line chemotherapy consisting of ACy (Adriamycin + Cyclophosphamide), PCy (Cisplatin ... a total of 4-6 cycles (table 2). The toxicity in treatment with Cisplatin consisted of nausea and vomiting in 38 patients (62.3% of Cisplatin-treated patients); this was WHO grade 3 in 17 pts...
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báo cáo hóa học:

báo cáo hóa học:" The prosurvival activity of ascites against TRAIL is associated with a shorter disease-free interval in patients with ovarian cancer" docx

... treated with increasing concentrations of TRAIL for 48 h or with cisplatin orpaclitaxel for 72 h. Cell viability was assessed by XTT assays. TRAIL,cisplatin and paclitaxel IC50were determined in ... 3:1http://www.ovarianresearch.com/content/3/1/1Page 2 of 10invasion of ovarian tumor s [27]. Activation of this path-way has been associated with cisplatin resistance in ovarian cancer [28]. In addition, the inhibition of Aktprevents ... G, Cassidy J, Eisenhauer E: Comparison of CA-125 and standard definitions of progression of ovarian cancer in theintergroup trial of cisplatin and paclitaxel versus cisplatin andcyclophosphamide....
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Báo cáo y học:

Báo cáo y học: "A severe coarctation of aorta in a 52-year-old male: a case report"

... Ascending aortography Figure 2 Descending aortography Discussion Aortic coarctation is a congenital vascular lesion typically diagnosed in early life, accounting for 5 to 10% of all ... a 52-year-old male. Our patient was relatively asymptomatic until he presented with chest discomfort, fatigue and dyspnea in his fifth decade of life. Conflict of interest None declared. ... time of cor-rection. Death in these patients is usually due to heart failure, coronary artery disease, aortic rup-ture/dissection, concomitant aortic valve disease, infective endarteritis/endocarditis,...
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Báo cáo y học:

Báo cáo y học: "A pilot study of rizatriptan and visually-induced motion sickness in migraineu"

... protective effect of a sero-tonin agonist for motion sickness in migraineurs with migraine-related dizziness. The pilot study reported herein extends this line of research by combining a visual motion ... this pilot study provides additional impetus for the possibility of using triptans for prophylaxis against motion sickness, especially in those migraineurs who have dizziness associated with ... anxiety, as reflected by subjective discomfort, was greater in the subjects with migrain-ous vertigo. This finding is consistent with the exces-sive vestibular symptoms in this group. Possibly,...
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Báo cáo y học:

Báo cáo y học: "A comparative analysis of antibody repertoire against Staphylococcus aureus antigens in Patients with Deep-Seated versus Superficial staphylococcal Infections"

... from 64% for assay of Abs against teichoic acid to 72% for assays of antibody to peptidoglycan and α-toxin. The specificity of assays for antibody to cell wall antigens (peptidoglycan and ... Kim for statistical analysis, David Griffith for photography and Dr. Fu-Shin Yu (Kresge Eye Institute) for his valuable critiques. Conflict of interest None declared. References 1. Lowy FD. ... antibody response against PG in some of the patients with deep infection might be due to impaired immunity of advancing age, poor expression of virulence determinants by the infecting strain...
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Báo cáo y học:

Báo cáo y học: "ribriform-Morular Variant of Papillary Carcinoma: Association with Familial Adenomatous Polyposis Report of Three Cases and Review of Literature"

... faculty for 10 years. Following that she worked at New York University for another 11 years. Her area of expertise is in Pulmonary Pathology, both diagnostic and research aspects. She is the ... describe a rare variant of papillary thyroid carcinoma (PTC), the Cribriform-Morular Variant (C-MV). A handful of cases have been described in the literature of this entity. They exhibit the ... the germline mutations [3]. They display the characteristic histologic pattern of cribriforming akin that seen in breast cancer with morules. Morules appear squamous with no keratinization...
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Tài liệu Báo cáo khoa học: A functional polymorphism of apolipoprotein C1 detected by mass spectrometry docx

Tài liệu Báo cáo khoa học: A functional polymorphism of apolipoprotein C1 detected by mass spectrometry docx

... survey of plasma proteins in approximately 1300 individuals byMALDI-TOF MS resulted in identification of a structural polymorphism of apolipoprotein C1 (ApoC1) that was found only in persons of ... identities are: 13762, the common form of TTr; 13881, the common form of TTrdisulfide-linked to cysteine; 13792, a variant form of TTr that mayconsist of G6S change; 13911, the variant protein that is ... with approval by the institutional review board of the University of Minnesota, and informed consent was obtained for pro-tein analysis of the samples to discover biomarkers. Bloodwas obtained by venepuncture,...
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Tài liệu Báo cáo khoa học: A unique variant of streptococcal group O-antigen (C-polysaccharide) that lacks phosphocholine ppt

Tài liệu Báo cáo khoa học: A unique variant of streptococcal group O-antigen (C-polysaccharide) that lacks phosphocholine ppt

... com-prised a delay time of 71 ms, corresponding to 7 Hzcouplings.Sugar and methylation analyses For sugar analysis, alditol acetates were prepared byhydrolysis of the polysaccharide using 2Mtrifluoroaceticacid ... yield of ribitol-containing oligosaccharide may beobtained if the temperature is kept lower when evaporatingthe HF to dryness.Analysis of PSII-OLS by ESI-MS in positive mode,showed singly ... °C for 2 h or 4MHCl at 120 °Cfor1h,followed by reduction with NaBH4or NaBD4,andacetylation. For methylation analysis, methylation wasperformed with methyl iodide in the presence of sodiummethyl...
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